It is my understanding that you still need a negative tissue control but if 
using a polymer detection kit that you may stop doing a negative reagent 
control.  The negative tissue control is a tissue known to not contain the 
antigen in the tissue, it can be an internal control, or a separate control but 
if internal control, then it must be designated as to how it will be used in 
your procedure manual.  Hope that helps.

Debbie Siena
800.442.3573 ext. 229 | www.statlab.com


-----Original Message-----
From: [email protected] 
[mailto:[email protected]] On Behalf Of 
[email protected]
Sent: Friday, December 28, 2012 2:19 PM
To: .
Subject: [Histonet] CAP and negative IHC controls

How is everyone interpreting the CAP rule about using negative controls? Do we 
still need a negative with each patient slide? 
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