I am not aware of any such studies [dealing with specimen sizes] but it is a 
known fact since early XXth century that large specimens [such as complete 
brain slices] are known to be processed and yes, they require extended 
dehydrtaion → clearing → infiltration but not much more than usual IF the 
slices are thin enough, and yes, automated tissue processors can be used [I 
have done them for brain and whole prostates].René J.  


     On Thursday, April 9, 2015 2:26 PM, Caroline Miller <mi...@3scan.com> 
wrote:
   

 Hi there wonderful Histonet people,

Has anyone seen any studies on the maximum size of tissue that can be
paraffin (or resin) processed. I am not talking about the size that can fit
in a tissue cassette, but, for example, entire pig bladder processing.

I realize it would include extended processing time, temp, vacuum,
agitation so imagine that none of these factors were limiting as I shall be
using an automated tissue processor.

I also realize that this is going to be tissue dependent. I was hoping
there were already some studies in this area that I am not finding in both
google and pubmed searches.

thanks, in advance, for any links you can point me to,

yours,
Caroline

-- 
Caroline Miller
Director of Histology
3Scan.com
415 2187297
_______________________________________________
Histonet mailing list
Histonet@lists.utsouthwestern.edu
http://lists.utsouthwestern.edu/mailman/listinfo/histonet


   
     On Thursday, April 9, 2015 2:26 PM, Caroline Miller <mi...@3scan.com> 
wrote:
   

 Hi there wonderful Histonet people,

Has anyone seen any studies on the maximum size of tissue that can be
paraffin (or resin) processed. I am not talking about the size that can fit
in a tissue cassette, but, for example, entire pig bladder processing.

I realize it would include extended processing time, temp, vacuum,
agitation so imagine that none of these factors were limiting as I shall be
using an automated tissue processor.

I also realize that this is going to be tissue dependent. I was hoping
there were already some studies in this area that I am not finding in both
google and pubmed searches.

thanks, in advance, for any links you can point me to,

yours,
Caroline

-- 
Caroline Miller
Director of Histology
3Scan.com
415 2187297
_______________________________________________
Histonet mailing list
Histonet@lists.utsouthwestern.edu
http://lists.utsouthwestern.edu/mailman/listinfo/histonet



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