Time alone is not the only cause for antigen decay for it is also associated 
with storage conditions and, as such, you cannot "predict" % decay based on 
time alone.Just try one block and let the pathologist decide based on the 
usefulness of what he sees in that try test.René 

    On Thursday, February 7, 2019 8:23 AM, "Heckford, Karen - SMMC-SF via 
Histonet" <histonet@lists.utsouthwestern.edu> wrote:
 

 Good Morning,
One of my Pathologists wants me to do some ER/PR's on 9 year old tissue blocks. 
 I know ER and PR can be sensitive are the IHC's going to work or will there be 
too much antigen decay?

Thanks,

Karen Heckford HT ASCP CE
Lead Histology Technician
St. Mary's Medical Center
450 Stanyan St.
San Francisco, Ca. 94117
415-668-1000 ext. 6167
karen.heckf...@dignityhealth.org

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