Karen Heckford HT ASCP CE at St. Mary's Medical Center in San Francisco, CA asks:
>>One of my pathologists wants me to do some ER/PR's on 9 year old tissue blocks. I know ER and PR can be sensitive are the IHC's going to work or will there be too much antigen decay?<< You can only try. There should be some antigen positive ducts and what have you in these 9 year old tissues that should serve as an internal control. If there's nothing positive, I'd interpret negative results cautiously. But it's worth a try. Bob Richmond Samurai Pathologist Maryville TN _______________________________________________ Histonet mailing list Histonet@lists.utsouthwestern.edu http://lists.utsouthwestern.edu/mailman/listinfo/histonet