(Instructions For Use) The paperwork that you receive with each reagent/solution/stain, etc.
> On Jul 22, 2020, at 3:10 PM, Muhammad Azam <ajj...@gmail.com> wrote: > > And IFU would be what > > Sent from my iPhone > >> On Jul 22, 2020, at 3:02 PM, Lynette Pavelich via Histonet >> <histonet@lists.utsouthwestern.edu> wrote: >> >> Carl, >> My only other thought is to do a documented study of the temperature of >> these outside storage boxes (they can be little hot/cold boxes depending on >> your location. Because, according to the inspectors, you must be able to >> assure temperature is within the required temps prior to receiving, >> including transportation. (Pre-analytical) >> So, say you do a study of the temperatures during the hottest time of the >> day of the boxes for a period of time (30 days of the hottest month(s)) to >> give an indication of a potential problem, and document. That would be one >> portion of pre-analytical. >> >> Then temperature during transportation (cars/vans can get quite hot/cold >> also needs to be addressed and documented daily just like the temperature >> logs in the labs. Many labs are getting cited for not providing good >> pre-analytical evidence. Courier services have to have temperature >> monitoring systems in place to provide as evidence. Some are quite savvy >> with alarm systems in place with monitoring. (ShipCom for example) >> >> So much documentation these days…… >> >> Lynette >> >> >>> On Jul 22, 2020, at 2:27 PM, Hobbs, Carl <carl.ho...@kcl.ac.uk> wrote: >>> >>> You a re right, Lynette >>> De rigueur for Diagnostic labs! >>> My apologies for forgetting that ( I am now in research labs where...it is >>> less restricted, unfortunately). >>> Essential to be well-documented/adherent to SOPs. >>> Respectful-illy >>> >>> Carl >>> >>> >>> Carl Hobbs FIBMS >>> Histology and Imaging Manager >>> Wolfson CARD >>> Guys Campus, London Bridge >>> Kings College London >>> London >>> SE1 1UL >>> >>> >>> 020 7848 6813 >>> >>> >>> From: Lynette Pavelich <lynette...@gmail.com> >>> Sent: 22 July 2020 19:19 >>> To: Hobbs, Carl <carl.ho...@kcl.ac.uk> >>> Cc: histonet@lists.utsouthwestern.edu <histonet@lists.utsouthwestern.edu> >>> Subject: Re: [Histonet] Warm formalin >>> >>> I would suggest to always refer to your reagent’s IFU insert. This will >>> advise at what temperature you should use/store. All inspectors (CAP, JC, >>> CLIA, etc.) will make you adhere to these specifications. >>> Unless you do a well documented validation study that goes outside of these >>> restrictions from the IFU that proves no patient harm, you honestly must go >>> by the IFU recommendations. This would apply to all of our >>> stains/reagents/solutions/antibodies. >>> Our world is becoming more restrictive…… >>> >>> hope this helps, >>> Lynette Pavelich, HT(ASCP), QIHC >>> >>> >>>>> On Jul 22, 2020, at 1:55 PM, Hobbs, Carl via Histonet >>>>> <histonet@lists.utsouthwestern.edu> wrote: >>>> >>>> Depends on what you are doing with the sections. >>>> IHC or just dye -staining? >>>> Sure...too hot ( cooking) is not recommended, as stated >>>> Also stated is that high -temp fixation may also be used with no >>>> deleterious effects as long as the fixation time is not extended. >>>> However, RT -ish even for a week won't be a problem...imho >>>> Needs must? >>>> >>>> >>>> >>>> Carl Hobbs FIBMS >>>> Histology and Imaging Manager >>>> Wolfson CARD >>>> Guys Campus, London Bridge >>>> Kings College London >>>> London >>>> SE1 1UL >>>> >>>> >>>> 020 7848 6813 >>>> _______________________________________________ >>>> Histonet mailing list >>>> Histonet@lists.utsouthwestern.edu >>>> https://eur03.safelinks.protection.outlook.com/?url=http%3A%2F%2Flists.utsouthwestern.edu%2Fmailman%2Flistinfo%2Fhistonet&data=01%7C01%7Ccarl.hobbs%40kcl.ac.uk%7C2915a105cfa5436de65e08d82e6bd68b%7C8370cf1416f34c16b83c724071654356%7C0&sdata=YZGiBCOwM5NmjBuxHh%2B%2FuhltOh%2F0HxJs5Kb8FaurKQM%3D&reserved=0 >> >> >> _______________________________________________ >> Histonet mailing list >> Histonet@lists.utsouthwestern.edu >> http://lists.utsouthwestern.edu/mailman/listinfo/histonet _______________________________________________ Histonet mailing list Histonet@lists.utsouthwestern.edu http://lists.utsouthwestern.edu/mailman/listinfo/histonet
