The GNAC firewalls list, it's stated as "well known" that several version 
of PIX firmware when runing "SMTP fixup" breaks Exchange and Notes, but not 
sendmail or postfix.

a couple of quotes:

"
>The explanation I got from Cisco is that Exchange 5.x / 2000 implements a 
>superset of ESMTP commands.  In fact with the fixup SMTP turned on the PIX 
>only listens to seven SMTP commands and ignores all ESMTP commands.  With 
>the fixup SMTP turned off, it should allow most if not all SMTP packets to 
>flow untouched.  The issue seems to be that the Exchange server insists 
>upon trying to use ESMTP for certain functions and may under certain 
>circumstances refuse to renegotiate and fall back to SMTP, when ESMTP 
>commands are blocked or not supproted.
"

and

"
The PIX SMTP fixup isn't broken.  It's an interpretation of RFC 821 for 
SMTP.  If you use it you need a SMTP compliant mail implementation.  PIX 
then intercepts and scrubs certain commands and data that appear in those 
connections as per RFC 821.

Postfix and other implementations work with fixup.  Some Exchange 
implementations work.  If you sniff the connection, or check the PIX logs 
you will see it is clearly due to their implementation of SMTP.

The PIX fixup does not work if you are using ESMTP.  That's clearly stated 
in the PIX documentation.  RFC 821 was never extended to cover 
ESMTP.  Many, many folks miss that point.
"

Len


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