Sorry, Brad, but I'm currently in Salt Lake at a funeral.  I'd really like to 
understand better so, if you're available, I can do it anytime during the week 
on another call.

Sent from Howling Fantods

> On Aug 1, 2014, at 7:36 AM, Bradley Lowekamp <[email protected]> wrote:
> 
> Nick,
> 
> I hope you can make it to today's TCON. I can demo that notebook I linked 
> too. It should clarify things.
> 
> Brad
> 
> On Jul 30, 2014, at 1:57 PM, Nicholas Tustison <[email protected]> wrote:
> 
>>> To try to summaries... sorry if have not been clear enough in my 
>>> explanations.
>> 
>> No, I blame me—I’m consistently distracted by the scenery outside here in
>> California and it’s definitely affecting my ability to concentrate on code
>> questions.
>> 
>>> INITIAL QUESTION
>>> 
>>> How does composite transform and the "Center" parameter interact? How does 
>>> this relate to the virtual domain?
>> 
>> The composite transform is agnostic with respect to whether or not a 
>> transform has a center or any other fixed parameter set.  The only
>> distinction we make is typology with respect to linear/deformable. To 
>> be clear, we’re not discussing any of the  “Centered” transforms:
>> 
>> * CenteredAffineTransform
>> * CenteredEuler3DTransform
>> * CenteredEuler2DTransform
>> * CenteredSimilarity2DTransform
>> 
>> None of those transforms are used in ANTs but I don’t think 
>> their optimization would be an issue in the new ITKv4 registration 
>> framework.
>> 
>> The virtual domain is simply defined in terms of standard image 
>> geometry (origin, spacing, etc.) and is currently set in terms of the 
>> fixed image geometry.  
>> 
>>> MY UNDERSTANDING
>>> 
>>> 1) Using a "Center" initialized transform only works correctly for a single 
>>> transform and directly with a composite. ( This is with the current center 
>>> initializers, a different approach could be done which takes into 
>>> consideration the composition )
>> 
>> I don’t see why it would only work correctly for a single transform.  Suppose
>> I optimize a translation transform to get it’s optimal parameters for a given
>> registration problem.  It’s not clear to me why it would be a problem to 
>> follow
>> that with optimizing an Euler3D transform (which we do all the time in 
>> ANTs).  
>> Obviously, we have to specify a staring point for the second transform (which
>> is identity by default) and perhaps it would be better to have a different 
>> starting point but I don’t see why starting with the default parameters is a 
>> problem.
>> 
>> If the “Center initialized transform” is one of the transforms listed above 
>> then we don’t use those.  If it’s simply the result of using the 
>> CenteredTransformInitializer, then we just pull the 
>> itk::TranslationTransform 
>> part from the result and push that translation transform into the composite 
>> transform queue.   I don’t see why it would be a problem to then optimize, 
>> for example, the Euler3DTransform which just has 3 translation parameters 
>> and 3 angle parameters to optimize where the center is implicitly defined 
>> (unlike the CenteredEuler3DTransform which does have additional Center 
>> parameters).  
>> 
>>> 2) The virtual domain should be initialized such that the two images 
>>> "Center"s are at the origin. This an alternative to using the "Center" 
>>> transform parameters, and better works with composite transforms.
>> 
>> Yes, that would probably be a better initialization but I don’t know why it 
>> would
>> be a problem for the current framework to optimize with the origin elsewhere.
>> Right now, each transform within the composite transform queue is 
>> optimized starting from its identity parameters but perhaps the initializer
>> idea that you propose would improve optimization. 
>> 
>>> I was not aware that 2 was the best practice with the ITKv4 framework. Do 
>>> we have any examples/test/documentation to indicate this?  Further more 
>>> using the current CenterTransformInitalizers to initialize the virtual 
>>> domain is not readily apparent[1] how to map the parameters.
>>> PROPOSAL
>>> 
>>> Perhaps we need a new Initializer filter to assist with initializing the 
>>> virtual domain to initialize this practice? 
>>> 
>>> Brad
> 
_______________________________________________
Powered by www.kitware.com

Visit other Kitware open-source projects at
http://www.kitware.com/opensource/opensource.html

Kitware offers ITK Training Courses, for more information visit:
http://kitware.com/products/protraining.php

Please keep messages on-topic and check the ITK FAQ at:
http://www.itk.org/Wiki/ITK_FAQ

Follow this link to subscribe/unsubscribe:
http://public.kitware.com/mailman/listinfo/insight-developers

Reply via email to