I don't understand the part of your question about it working without a screen 
reader.  As far as that goes its like any other piece of software if the person 
needs a screen reader then they'll need one with Dragon.  

If they are trying to run Dragon and Jaws then they need JSay, the Jaws 
interface programme.  Since Dragon responds to verbal commands it hears its 
really pretty impossible to work it without an interface because it hears and 
tries to respond to Jaws.

Hope your friend finds a system that works for them!
Joy
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