Hello, Nanthini

Clearing models once and again could lead you into memory use problems, 
but you can certainly try.
The command you need to clear a whole model loaded is
 zap file
 zap model

See http://www.stolaf.edu/academics/chemapps/jmol/docs/#zap

Example:
load mol1.pdb;
load append mol2.pdb;
zap file=1;  //will remove mol1.pdb





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