On Wed, 23 Aug 2006, Steffen Durinck wrote:

> Is it possible that this is caused by people who e.g. try to annotate a 
> long list (>10000) of gene ids with GO annotation by looping over these 
> ids and firing a query for every id separately? I've noticed that users 
> of the biomaRt R package sometimes construct these loops although we 
> strongly advice against it.

think it is probably something similar but being fired off from Taverna 
pipelines

cheers
Damian


> 
> best,
> Steffen
> 
> 
> Damian Smedley wrote:
> > On Wed, 23 Aug 2006, Steffen Durinck wrote:
> >
> >   
> >> Hi all,
> >>
> >> The BioMart central service seems to have been down the last few days.  
> >> Yesterday it came back on-line but when doing a query to read the 
> >> central server registry gives:
> >> http://www.biomart.org/biomart/martservice?type=registry
> >>     
> >
> > there have been problems with people hammering the central server with 
> > martservice requests. We are investigating how to solve this - probably IP 
> > banning I think.
> >
> > I think the problem below is with the proxy - hopefully I will restart the 
> > server with the correct settings in a few minutes
> >
> > thanks
> > Damian
> >
> >
> >
> >   
> >> <MartRegistry>
> >>   <virtualSchema name="dicty" visible="0">
> >>     <MartURLLocation default="1" displayName="DICTYBASE (NORTHWESTERN)" 
> >> host="www.dictybase.org" includeDatasets="" martUser="" name="dicty" 
> >> path="" port="80" redirect="1" serverVirtualSchema="dictyMart" visible="1" 
> >> />
> >>   </virtualSchema>
> >>   <virtualSchema name="default" visible="0">
> >>     <MartURLLocation default="1" displayName="ENSEMBL 40 (SANGER)" 
> >> host="web50-node4.ebi.ac.uk" includeDatasets="" martUser="" name="ensembl" 
> >> path="/biomart/martservice" port="9004" serverVirtualSchema="default" 
> >> visible="1" />
> >>     <MartURLLocation default="0" displayName="SEQUENCE 40 (SANGER)" 
> >> host="web50-node4.ebi.ac.uk" includeDatasets="" martUser="" 
> >> name="sequence" path="/biomart/martservice" port="9004" 
> >> serverVirtualSchema="default" visible="0" />
> >>     <MartURLLocation default="0" displayName="SNP 40 (SANGER)" 
> >> host="web50-node4.ebi.ac.uk" includeDatasets="" martUser="" name="snp" 
> >> path="/biomart/martservice" port="9004" serverVirtualSchema="default" 
> >> visible="1" />
> >>     <MartURLLocation default="0" displayName="VEGA 40 (SANGER)" 
> >> host="web50-node4.ebi.ac.uk" includeDatasets="" martUser="" name="vega" 
> >> path="/biomart/martservice" port="9004" serverVirtualSchema="default" 
> >> visible="1" />
> >>     <MartURLLocation default="0" displayName="UNIPROT PROTOTYPE 4-5 (EBI)" 
> >> host="web50-node4.ebi.ac.uk" includeDatasets="" martUser="" name="uniprot" 
> >> path="/biomart/martservice" port="9004" serverVirtualSchema="default" 
> >> visible="1" />
> >>     <MartURLLocation default="0" displayName="MSD PROTOTYPE 4 (EBI)" 
> >> host="web50-node4.ebi.ac.uk" includeDatasets="" martUser="" name="msd" 
> >> path="/biomart/martservice" port="9004" serverVirtualSchema="default" 
> >> visible="1" />
> >>     <MartURLLocation default="0" displayName="WORMBASE CURRENT (CSHL)" 
> >> host="web50-node4.ebi.ac.uk" includeDatasets="" martUser="" 
> >> name="wormbase" path="/biomart/martservice" port="9004" 
> >> serverVirtualSchema="default" visible="1" />
> >>   </virtualSchema>
> >> </MartRegistry>
> >>
> >>
> >> The host is said to be web50-node4.ebi.ac.uk but this is not accessible.
> >> Any idea what is happening or how we can access the web services again?
> >>
> >> best,
> >> Steffen
> >>
> >> -- 
> >> Steffen Durinck, Ph.D.
> >>
> >> Oncogenomics Section
> >> Pediatric Oncology Branch
> >> National Cancer Institute, National Institutes of Health
> >> URL: http://home.ccr.cancer.gov/oncology/oncogenomics/
> >>
> >> Phone: 301-402-8103
> >> Address:
> >> Advanced Technology Center,
> >> 8717 Grovemont Circle
> >> Gaithersburg, MD 20877
> >>
> >>     
> 
> 
> -- 
> Steffen Durinck, Ph.D.
> 
> Oncogenomics Section
> Pediatric Oncology Branch
> National Cancer Institute, National Institutes of Health
> URL: http://home.ccr.cancer.gov/oncology/oncogenomics/
> 
> Phone: 301-402-8103
> Address:
> Advanced Technology Center,
> 8717 Grovemont Circle
> Gaithersburg, MD 20877
> 

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