Once one or more vaccines are available I wonder what the antivaxxer rate will be.... of people who refuse under any circumstances to get inoculated.
On Tue, Sep 15, 2020 at 10:29 AM Dan Penoff via Mercedes < mercedes@okiebenz.com> wrote: > This is informative. Thank you! > > -D > > > On Sep 15, 2020, at 10:04 AM, Buggered Benzmail via Mercedes < > mercedes@okiebenz.com> wrote: > > > > Vaccine trials going on now. 3 friends (One immunologist prof who > developed her own antibody tests and is on the biosafety committee at the > hospital, another who is MD/PhD on boards of various drug companies and > affiliated with drug development efforts at the hospital, and his wife) got > the first Astra Zeneca doses (maybe, 2/3 chance in this trial, others are > 50/50) 2 weeks ago locally. Trials were briefly suspended last week after a > possibly (but not likely)-related illness in U.K. But will likely resume > maybe this week after NIH give the go-ahead. A/Z are doing trials in U.K. > US and Brazil. > > > > I had some beers with my MD/PhD buddy last night and we discussed this > in some detail. They get a second dose likely next week, and blood draws to > monitor responses. > > > > There are 2 other trials going on locally too for other vaccines. (The > different vaccines address different biological aspects of the virus, I > forget the specific chemistry he told me but it has to do with the > structure and function of the virus, which is actually pretty nasty and > unique, hence the vaccine challenges and possibly different > effectivenesses). > > > > He says one vaccine would likely give 50-70% immunity, you can take 2 or > 3 different types and that would boost your likely immunity up pretty high > (flu shots are like 70% effective for a comparison) and would last maybe a > coupla years as your biology kinda winds down after awhile and forgets > about it. > > > > My immunologist friend is tempted to run her own antibody test on > herself to see if she got the dose or placebo. Or maybe a friend might do > it... > > > > I signed up for the A/Z trial with the higher (2/3) dose probability and > am waiting to hear in the next coupla weeks after the initial tranche (60 > people) are observed and the trial resumes. They had 3000 people sign up , > he thinks I have a pretty good chance (nudge nudge wink wink) of getting > invited in. If you get the actual dose, and it actually works, your > immunity would develop over a month or two, it is not necessarily > immediate, which is how these things work. And even if tests don’t show you > have the antibodies, you might still have immunity because humans have > different mechanisms (I think he told me there are 3 mechanisms) for > immunity not all of which will show up on the easier tests. So a lot of it > is biology and not really “testable” for immediate results. > > > > He figures there should be some strong clinical results over the next > 3-4 months and vaccines should start becoming available in 4-6 months if > all goes well. And again you could take 2 or 3 different vaccines if > available. Yes it takes time but this is actually pretty accelerated given > the biology of it all. > > > > So that is probably as much as anyone knows (dumbed down a bit for my > consumption) coming from someone right in the middle of it all. I think I > got most of it right, there was beer involved... It was all quite > informative and encouraging, but practically drug development takes time > and this is being accelerated but still trying to maintain safety. > > > > --FT > > Sent from iPhone > > > >> On Sep 15, 2020, at 7:59 AM, Curt Raymond via Mercedes < > mercedes@okiebenz.com> wrote: > >> > >> What do you give the odds of a vaccine in the next year or so? I know > a lot of folks are busting hump to get one but it seems unlikely to me > considering the fastest vaccine ever took 4 years... > >> -Curt > >> > >> On Tuesday, September 15, 2020, 12:49:57 AM EDT, archer75--- via > Mercedes <mercedes@okiebenz.com> wrote: > >> > >>> On Sun, 13 Sep 2020 16:08:21 +0000 > >>> Rick Knoble via Mercedes <mercedes@okiebenz.com> wrote: > >>> > >>> Long time, no hear... > >> > >>> Rick > >>> _______________________________________ > >> > >> Hi Rick, > >> I'm still here; enjoying all the activity on Okiebenz. > >> Looking forward to an effective vaccine. > >> Thanks for your concern. > >> Gerry > >> > >> -- > >> This email has been checked for viruses by AVG. > >> https://www.avg.com > >> > >> > >> _______________________________________ > >> http://www.okiebenz.com > >> > >> To search list archives http://www.okiebenz.com/archive/ > >> > >> To Unsubscribe or change delivery options go to: > >> http://mail.okiebenz.com/mailman/listinfo/mercedes_okiebenz.com > >> > >> > >> _______________________________________ > >> http://www.okiebenz.com > >> > >> To search list archives http://www.okiebenz.com/archive/ > >> > >> To Unsubscribe or change delivery options go to: > >> http://mail.okiebenz.com/mailman/listinfo/mercedes_okiebenz.com > >> > > > > _______________________________________ > > http://www.okiebenz.com > > > > To search list archives http://www.okiebenz.com/archive/ > > > > To Unsubscribe or change delivery options go to: > > http://mail.okiebenz.com/mailman/listinfo/mercedes_okiebenz.com > > > > > _______________________________________ > http://www.okiebenz.com > > To search list archives http://www.okiebenz.com/archive/ > > To Unsubscribe or change delivery options go to: > http://mail.okiebenz.com/mailman/listinfo/mercedes_okiebenz.com > > _______________________________________ http://www.okiebenz.com To search list archives http://www.okiebenz.com/archive/ To Unsubscribe or change delivery options go to: http://mail.okiebenz.com/mailman/listinfo/mercedes_okiebenz.com
