Prasugrel is a platelet inhibitor. Warfarin is a vitamin K-dependent
clotting factor inhibitor (II, VII, IX, X). Xarelto and other doacs inhibit
specific clotting factors (eg Xa and II). All of these factors and
platelets play roles in the cascade leading to blood clot formation.

On Thu, May 6, 2021, 2:04 PM Curt Raymond via Mercedes <
mercedes@okiebenz.com> wrote:

>  It's not that you don't clot, it's that clotting is reduced. I suppose
> different medications act differently but at least with the Prasugrel that
> I use I just bleed a little more when I get cut. It's not dramatic which is
> good because I cut myself a lot...
> -Curt
>
>     On Thursday, May 6, 2021, 11:09:49 AM EDT, Meade Dillon via Mercedes <
> mercedes@okiebenz.com> wrote:
>
>  So if you accidentally get a cut or severe injury, you won't bleed out (if
> you have the antidote and a tourniquet ready).
> -------------
> Max
> Charleston SC
>
>
> On Thu, May 6, 2021 at 11:06 AM Kaleb Striplin via Mercedes <
> mercedes@okiebenz.com> wrote:
>
> > That is my understanding. With the new ones there is not a way to reverse
> > it quickly, have to wait for it to wear off. With the older ones you can.
> >
> > Sent from my iPhone
> >
> > > On May 6, 2021, at 8:56 AM, Max Dillon via Mercedes <
> > mercedes@okiebenz.com> wrote:
> > >
> > > Does this thinner also have the advantage of an antidote (probably not
> > the right word) that reverses the effect on the event of an emergency or
> > surgery?  I think the newer medications do not enjoy this feature.
> > >
> > > Max Dillon
> > > Charleston SC
> > >
> > >
> > > May 6, 2021 9:25:55 AM Karl Wittnebel via Mercedes <
> > mercedes@okiebenz.com>:
> > >
> > >> The evidence for the DOACs like Xarelto for antiphopholipid antibody
> is
> > not
> > >> as strong as the evidence for warfarin. There is some suggestion that
> > >> Xarelto etc may not work as well for arterial clots, though they both
> > seem
> > >> to work OK for venous clots. Anyway it has not been super well studied
> > but
> > >> until there is a good study showing comparable efficacy with both
> drugs
> > in
> > >> a large number of patients, the recommendation will likely continue to
> > be
> > >> for warfarin. At least that is my understanding.
> > >>
> > >>> On Thu, May 6, 2021 at 6:18 AM Kaleb Striplin via Mercedes <
> > >>> mercedes@okiebenz.com> wrote:
> > >>>
> > >>> As you may recall a while back I was in the hospital due to blood
> > clots.
> > >>> They put me on Xarelto. It was still a mystery as to why this
> happened
> > in
> > >>> the first place. My primary doctor sent me to a cancer doctor to
> > figure it
> > >>> out. Went back to him for the 2nd time last week to run tests. Turns
> > out I
> > >>> evidently have something called antiphospholid antibody syndrome.
> They
> > are
> > >>> moving me from Xarelto to Coumadin for some reason which will require
> > me to
> > >>> get blood tests weekly for a few weeks then monthly after. I guess I
> > will
> > >>> ask but not sure why they would take me off the newer state of the
> art
> > >>> blood thinner that requires no testing to this older cheaper
> medication
> > >>> that does.
> > >>>
> > >>> Sent from my iPhone
> > >>>
> > >>> _______________________________________
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