In <[email protected]>,
 Arne K Christensen <[email protected]> wrote:

> I have run dot blots with nitrocellulose membrane before; simply add 
> 10ul samples in RSB directly to membrane and wait for them to dry, then 
> block and continue with the Western blot.  However, we only have PVDF 
> membranes on hand right now.  Has anybody here run dot blots on PVDF 
> membrane.  Do you apply the sample to the dry PVDF membrane before the 
> methanol soak?  Will proteins bind to the membrane before the methanol soak?

I have methanol soaked, then soaked in transfer buffer, than 
soaked in TTBS, and used it wet in the dot blotter with very very low
vacuum.

AC
-- 
Email: echo 36434455860060025978157675027927670979097959886449930P | dc
_______________________________________________
Methods mailing list
[email protected]
http://www.bio.net/biomail/listinfo/methods

Reply via email to