Rupali Mukherjee

11-Jul-2013

NEW DELHI: UK drug regulator, Medicines and Healthcare products Regulatory 
Agency (MHRA) on Thursday said it would recall certain medicines from 
pharmacies and clinics in the UK made by Wockhardt after it found deficiencies 
in manufacturing procedures at Wockhardt's Waluj plant.

In May, the US Food and Drug Administration had imposed an "import alert" on 
Wockhardt's Waluj plant.

"This follows manufacturing deficiencies identified by the MHRA at Wockhardt's 
Waluj site in India," MHRA said in a statement.

The sixteen 'prescription only medicines' include those used for the treatment 
of infections, high blood pressure, diabetes, epilepsy, depression, 
schizophrenia, Parkinson's disease, dementia in Alzheimer's patients and 
thyroid conditions, it added.

Earlier, Wockhardt had said that the FDA's 
 action potentially affected around $100 million in revenue on an annualised 
basis. An "import alert", effectively a ban, results in the detention of drugs, 
without physical examination, from companies that have not met good 
manufacturing practices, according to the FDA website.

The MHRA said that the deficiencies found in Wockhardt's medicines were 
identified during a routine inspection in March. It found a low risk of 
cross-contamination because of poor cleaning practices and defects in a 
ventilation system.

The Waluj facility makes injectables and solid dosages. MHRA's Director of 
Inspection Enforcement and Standards Gerald Heddell said: "This is a 
precautionary recall. People can be reassured that there is no evidence that 
medicines made by Wockhardt are defective so it's important people continue to 
take their medicines as prescribed."

This is not a patient level recall because although the medicines that are 
affected have not been man
 ufactured to Good Manufacturing Practice (GMP) standards, there is no evidence 
of a patient safety risk from medicines that have been sold in the UK, MHRA 
said.

There was also evidence of forged documents relating to staff training records 
that had been rewritten, MHRA said. The UK drug regulator said it is working 
with Wockhardt and other international regulators to resolve these issues.

http://articles.timesofindia.indiatimes.com/2013-07-11/india/40513160_1_healthcare-products-regulatory-agency-mhra-wockhardt



                                          

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