Yes, I too at one time bought a huge case. Has 10 5.25 bays. Only problem is that you can't use all of them due to cable length limitations.
Multiple controllers?
I have one of these, http://calpc.com/catalog/mid_tower.html, and its quite beefy.
Their web site lists that it can take *one* hot-swap power supply. Not quite sure of the point of that...