sounds like the largefiles issue, you should have seen this warning during the build:
Your Perl is uselargefiles enabled, but Apache is not, suggestions:
*) Rebuild mod_perl with Makefile.PL PERL_USELARGEFILES=0
*) Rebuild Apache with CFLAGS="-D_LARGEFILE_SOURCE -D_FILE_OFFSET_BITS=64"
*) Rebuild Perl with Configure -Uuselargefiles
*) Let mod_perl build Apache (USE_DSO=1 instead of USE_APXS=1)
easiest fix is the 1st option.
