----- Forwarded message from "Schmidt, Eric" -----
Date: Mon, 2 Jun 2014 16:34:35 -0400
From: "Schmidt, Eric"
Reply-To: "Schmidt, Eric"
Subject: cluster analysis advice
To: "[email protected]"
I'd like to ask for some advice on using kinds of cluster analysis for a
morphological data set. Shape is not involved. I have data on the weights of
certain organs from numerous mice. These included things like livers, spleens,
hearts, and kidneys, dissected from adult mice. One aim is to take the data
and find modular patterns within them, without making any a priori hypotheses.
I'd also do this with the body weight residuals of all the organs.
One method I will try is to do a PCA, using organ types as the variables. If
different organ types tend to group and cluster, perhaps those "clusters" could
be used as a priori hypotheses in a PLS regression. Another way to group
organs might be to base clusters on germ layers, and do PLS. However, I'd
like some advice on a method or set of methods that will do a cluster analysis
independent of an initial hypothesis.
Thank you
Eric
Wash U
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