> 
> Sorry for the late response but I'm afraid i can't follow you. I searched for 
> high end nixie drivers but I couldn't find it (or I missed it).
> Can you explain what you wrote in an easy way? Thanks.

One simple approach I use often is a device known as an optocoupler for the 
anode drive.  These work by containing an LED (which is operated by your 
controller) shining on a phototransistor.  They provide solid isolation between 
the high voltage and your CPU, they're easy to drive (like any other LED), and 
can even provide current gain.  They tend to turn on and off a little slowly, 
so they're not useful for very high speed multiplexing, but for ordinary 
multiplexing and PWM dimming, they're fine, and the slower edges can reduce 
both electrical and audible interference.  You need to choose units that can 
withstand your anode supply voltage, and carry enough current for the tubes 
they're switching.  One suitable candidate is the Fairchild FOD852, which is 
easily available, costs 80 cents (US) in single quantities, is housed in a 
breadboard-friendly 4-pin DIP package, and is good for 300 volts and 150mA.  
Note that the minimum guaranteed current gain is only 10, so you shouldn't 
count on driving a lot of large tubes at once with just one of these, but for 
most purposes it'll be quite sufficient.

- John

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