*Alzheimer's risk high among lonely souls!*

 Lonely people may face the risk of developing *Alzheimer's
disease*<http://search.live.com/results.aspx?q=Alzheimer%27s+disease&mkt=en-IN&form=QBRE&go.x=3&go.y=12>,
a progressive brain disorder that gradually destroys a person's memory and
ability to reason or make judgments, according to a study.

Professor Robert Wilson and colleagues at Rush University Medical Centre
studied more then 800 elderly patients who were followed over a four-year
period, reported the online edition of BBC News.

The researchers assessed the loneliness of participants by asking people to
rate from one to five whether they agreed with certain statements related to
loneliness on an annual basis.

The researchers said in the "Archives of General Psychiatry" journal that
apart from an emotional impact, loneliness has a physical impact, too.
People who are lonely are twice as likely to develop Alzheimer's disease,
they added.

It may be that loneliness affects brain systems dealing with cognition and
memory, making lonely people more vulnerable to effects of age-related
decline in neural pathways, Wilson said.

"This is an impressive study. It follows a large group of people for a
significant period of time and comes up with startling findings that back up
earlier studies examining social interaction and Alzheimer's risk," said
Rebecca Wood, the chief executive of the Alzheimer's Research Trust.

"What I find particularly interesting about this study is the fact that it
is an individual's perception of being lonely rather than their actual
degree of social isolation that seems to correlate most closely with their
Alzheimer's risk," she added.

Social isolation has already been shown to be linked to dementia, but this
is the first time researchers have looked at how alone people actually felt.



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