Linear Mixed Models for Longitudinal Data by Geert Verbeke <http://www.amazon.com/exec/obidos/search-handle-url/102-2006236-4753744 ?%5Fencoding=UTF8&search-type=ss&index=books&field-author=Geert%20Verbek e> , Geert Molenberghs <http://www.amazon.com/exec/obidos/search-handle-url/102-2006236-4753744 ?%5Fencoding=UTF8&search-type=ss&index=books&field-author=Geert%20Molenb erghs>
Yaning Wang, Ph.D. Team Leader, Pharmacometrics Office of Clinical Pharmacology Office of Translational Science Center for Drug Evaluation and Research U.S. Food and Drug Administration Phone: 301-796-1624 Email: [EMAIL PROTECTED] "The contents of this message are mine personally and do not necessarily reflect any position of the Government or the Food and Drug Administration." ________________________________ From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] On Behalf Of Mark Sale - Next Level Solutions Sent: Tuesday, September 02, 2008 1:28 PM To: nmusers@globomaxnm.com Subject: [NMusers] unbalanced design Does anyone have a reference to a publication assessing whether mixed effect modeling (NONMEM in particular) is robust for unbalances studies? I see if in a number of courses (including the original beginners course for NONMEM), but can't find a publication. thanks Mark Sale MD Next Level Solutions, LLC www.NextLevelSolns.com 919-846-9185
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