Post Doctoral Opportunity:  Joint Modelling of Longitudinal and Survival
Data in Oncology Patients to Assist Early Decision Making in Clinical
Development.

We're currently looking for talented scientists to join our innovative
academic-style Postdoc. From our centre in Waltham USA you'll be in a
global pharmaceutical environment, contributing to live projects right from
the start. You'll take part in a comprehensive training programme,
including a focus on drug discovery and development, given access to our
existing Postdoctoral research, and encouraged to pursue your own
independent research in cutting edge laboratories. It's a newly expanding
programme spanning a range of therapeutic areas across a wide range of
disciplines.

About AstraZeneca
AstraZeneca is a global, innovation-driven biopharmaceutical business that
focuses on the discovery, development and commercialisation of prescription
medicines for some of the world's most serious diseases. But we're more
than one of the world's leading pharmaceutical companies. At AstraZeneca,
we're proud to have a unique workplace culture that inspires innovation and
collaboration. Here, employees are empowered to express diverse
perspectives - and are made to feel valued, energised and rewarded for
their ideas and creativity.

Description
This is a postdoctoral position in the area of statistical modelling in
oncology. The individual will be based in the Department of Quantitative
Clinical Pharmacology in AstraZeneca in Waltham, MA, and will be a member
of the Interdisciplinary Program in Pharmacometrics which links
pharmacometric experts across the Scientific Core Platforms.

As a Postdoctoral Scientist in Pharmacometrics and Statistics it's
essential that you have:

* A PhD with a track record of productivity in the areas of statistics,
pharmacometrics, mathematics, engineering or related field, as manifested
in publications and presentations
* Good written and verbal communication skills as the position will require
working with colleagues in cross-geographic locations
* Good team-worker in a multidisciplinary environment
* The ability to share knowledge and interpret findings
* A strong scientific track record, as evidenced by published or accepted
papers in peer-reviewed journals, oral and/or poster presentations at
scientific meetings

The following skills and qualifications are desirable:

* An understanding of pharmacology safety, pharmacokinetic, pharmacodynamic
and oncology therapeutic areas
* Mathematical or statistical modelling, with experience in modelling
biological data
* Hands-on familiarity with software platforms such as R, SAS, NONMEM,
MATLAB, Phoenix or other software/scripting languages
* The capability and drive for performing applied pharmacometrics research,
without the need for close supervision

As a Postdoctoral Scientist in Pharmacometrics and Statistics you will be:
* Involved in the development of statistical and pharmacological models in
oncology, working as part of a modelling team and collecting clinical data
in oncology, both from the public domain and in-house data
* Data assembling and manipulating using programs such as R and SAS, and
developing joint models of longitudinal and survival data with the
collected dataset
* Developing skills in both clinical pharmacology and pharmacometrics and
its impact on the drug development process, especially in the oncology
therapeutic area
* Actively engaging with all AstraZeneca and academic supervisors and
collaborating with other scientists
* Communicating the results of modelling in presentations to key
stakeholders and publishing scientific papers describing findings and any
novel method/approaches



To apply for this position, please contact Hongmei Xu (
hongmei...@astrazeneca.com)



*Hongmei Xu*, Ph.D.

Senior Pharmacometrician, Director

------------------------------------------------------------------------------------------------------
*AstraZeneca*

*R&D | Innovative Medicines*|Quantitative Clinical Pharmacology

B0.12, 35 Gatehouse Dr, Waltham, MA  02451

Email: hongmei...@astrazeneca.com

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