Post Doctoral Opportunity - Drug Safety Metabolism * Reference Number: PostDoc 112 * Career Area: Drug Safety Metabolism IMED<http://jobs.astrazeneca.com/jobs/category/drug-safety-metabolism-imed> Location(s): * United Kingdom<http://jobs.astrazeneca.com/jobs/country/united-kingdom>(Cambridge) Apply<http://gs.globalsuccessor.com/fe/tpl_astrazenecav2.asp?newms=ap&id=64486&rd=> Description Development of a haematopoiesis model that can be used for translational clinical predictions of bone marrow toxicity. We're currently looking for talented scientists to join our innovative academic-style Postdoc, on a 2 year Fixed Term Contract. From our centre in Cambridge, UK, you'll be in a global pharmaceutical environment, contributing to live projects right from the start. You'll take part in a comprehensive training programme, including a focus on drug discovery and development, given access to our existing Postdoctoral research, and encouraged to pursue your own independent research in cutting edge laboratories. It's a newly expanding programme spanning a range of therapeutic areas across a wide range of disciplines. What's more, you'll have the support of a leading academic advisor, who'll provide you with the guidance and knowledge you need to develop your career. This is an exciting area that hasn't been explored to its full potential, making this an opportunity to make a real difference to the future of medical science.
About AstraZeneca AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialisation of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energised and rewarded for their ideas and creativity. Therapy Area One of the greatest challenges when discovering and formulating effective medicines lies in mapping their pharmacokinetic properties - how they'll react within the human body. Here, you'll ensure our drug products are safe for clinical trials, and ultimately safe to deliver as novel treatments to our patients. To make that happen, you'll be working with truly cutting-edge in silico, in vivo, cellular and molecular technologies to push the boundaries of predictive science. Role Description If you're keen to help improve effectiveness of anti-cancer therapies this Post Doc will give you the opportunity to investigate how stem cell biology gives rise to regeneration of adult tissues and develop mechanistic understanding of Oncology agents' toxicity. As a Postdoctoral Scientist in DSM it's essential that you have: * A PhD in relevant discipline, such as Biological Engineering, Systems Biology, Biology, Maths, Engineering or Physics * Experience with model building software like Matlab or Berkeley Madonna * A proven record of publication in reputable scientific journals * Hands-on experience with quantitative techniques like systems biology or systems pharmacology * The confidence to creatively explore alternative modelling approaches The following skills and qualifications are desirable: * Knowledge of cancer biology, including DNA damage response and apoptosis pathways * A firm understanding of the haematopoiesis process * Experience of modelling cell populations such as stem cells, cellular differentiation or cell cycle * Expertise in drug toxicology, immunological techniques or flow cytometry As a Postdoctoral Scientist in DSM you will: * Quantify the impact of Oncology drugs and drug combinations on bone marrow cell populations and assess how this impacts blood cell count * Optimise oncology therapies to translate preclinical findings into human models * Collaborate with other experts in a wide range of areas and fields Additional information: To apply for this position, please click the apply link. AstraZeneca welcomes applications from all sections of the community. An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, or protected veteran status and will not be discriminated against on the basis of disability. This is a 2 year Fixed Term Contract opportunity with a competitive salary on offer. Closing Date: Midnight - 8th April 2016 Apply<http://gs.globalsuccessor.com/fe/tpl_astrazenecav2.asp?newms=ap&id=64486&rd=> http://jobs.astrazeneca.com/jobs/details/l1rPostDoc+112-post-doctoral-opportunity-drug-safety-metabolism ________________________________ AstraZeneca UK Limited is a company incorporated in England and Wales with registered number: 03674842 and a registered office at 2 Kingdom Street, London, W2 6BD. Confidentiality Notice: This message is private and may contain confidential, proprietary and legally privileged information. If you have received this message in error, please notify us and remove it from your system and note that you must not copy, distribute or take any action in reliance on it. Any unauthorised use or disclosure of the contents of this message is not permitted and may be unlawful. Disclaimer: Email messages may be subject to delays, interception, non-delivery and unauthorised alterations. Therefore, information expressed in this message is not given or endorsed by AstraZeneca UK Limited unless otherwise notified by an authorised representative independent of this message. No contractual relationship is created by this message by any person unless specifically indicated by agreement in writing other than email. Monitoring: AstraZeneca UK Limited may monitor email traffic data and content for the purposes of the prevention and detection of crime, ensuring the security of our computer systems and checking compliance with our Code of Conduct and policies.
