you can treat it as any other value below quantification limit, and
either comment it out (if you do this with other BQLs) or use it (same
as other BQLs)
Leonid
On 6/2/2020 2:13 PM, Nyein Hsu Maung wrote:
Dear NONMEM users,
I tried to simulate a new dataset by using a previously published pop pk model.
Their model was described by combined error model for residual variability. And
after simulation, I have obtained two negative concentrations. I would like to
know if there is any proper way to handle those negative concentrations or if
there are some codings to prevent gaining negative concentrations. Thanks.
Best regards,
Nyein Hsu Maung
