This is very similar to a situation I experienced the other day. It's all in a thread over on the Exchange list ("Exchange 2010 AD Topology service weirdness"). Unfortunately, I don't have a resolution for you. In addition to the Exchange issue, I saw exactly the same thing with slow logons, slow group policy processing, odd ping behavior, etc.
The only thing I could find that was related to what was going on (and only partially at that) was the kb article at http://support.microsoft.com/kb/2408181. Good luck. I hope you get this resolved. On Tue, Jul 3, 2012 at 1:07 PM, Glen Johnson <gjohn...@vhcc.edu> wrote: > Need help please. > We have 3 x 2008r2 domain controllers. > We've been fighting with some unusually slow domain logins and other > flakiness for a while. > For example navigating between OUs in active directory users and computers > is painfully slow. > While testing basic connectivity, I found that a ipv6 ping to one of our > domain controllers fails, but here is the interesting part. > If I ping -6 from domain controller to my workstation, then for a couple > minutes, ping -6 from my workstation to the domain controller works. > After just about 2 minutes, it begins failing again when I ping > workstation to server. Destination host unreachable is the error. > Ping -6 from my workstation to all other servers and domain controllers > work fine. > I checked the windows firewall on the failing computer and it looks > identical to the other 2 domain controllers. > One point that may be relevant. The failing DC has 2 nics. I did try > disabling one of the nics and rebooting. No help. > Turned windows firewall off, no help. > Any suggestions appreciated. > > ~ Finally, powerful endpoint security that ISN'T a resource hog! ~ > ~ <http://www.sunbeltsoftware.com/Business/VIPRE-Enterprise/> ~ > > --- > To manage subscriptions click here: > http://lyris.sunbelt-software.com/read/my_forums/ > or send an email to listmana...@lyris.sunbeltsoftware.com > with the body: unsubscribe ntsysadmin > > ~ Finally, powerful endpoint security that ISN'T a resource hog! ~ ~ <http://www.sunbeltsoftware.com/Business/VIPRE-Enterprise/> ~ --- To manage subscriptions click here: http://lyris.sunbelt-software.com/read/my_forums/ or send an email to listmana...@lyris.sunbeltsoftware.com with the body: unsubscribe ntsysadmin