These are most likely NDR's, emails for recipients who do not exist. If you haven't done so already you need to enable recipient filtering on your edge server. If you don't have an edge server then it needs to be enabled on your hub transport server using the anti-spam modules.
For us this took care of 85-95% of those type of NDR's. When we first noticed this issue I believe I googled "Message Source Name DSN". Jim From: Benjamin Zachary - Lists [mailto:li...@levelfive.us] Sent: Thursday, July 16, 2009 3:27 PM To: NT System Admin Issues Subject: RE: Exchange 07 I have massive amounts of garbage, the queues are filled with undeliverables from <> that have nothing but &^$^%$&^&)&#@ in them. Why would Exchange even queue this stuff they don't even appear to be 'valid' emails with a from/to or anything afaik. Anyway, I have to let them go through submission and then remove no/ndr every 10k or so. ~ Finally, powerful endpoint security that ISN'T a resource hog! ~ ~ <http://www.sunbeltsoftware.com/Business/VIPRE-Enterprise/> ~