> The original data was in CSV format. I read it in using pd.read_csv(). It 
> does have column names, but no row names. I don’t think numpy reads csv files
I routinely read csv files using numpy.loadtxt
https://docs.scipy.org/doc/numpy/reference/generated/numpy.loadtxt.html

> And also, when I do a[2:5]-b[:3], it does not throw any “index out of range” 
> error. I was able to catch that, but in both Matlab and R. You get an error. 
> This is frustrating!!
That's basic slicing behaviour of python. You might like it or not,
but it's baked into the language:
>>> [1,2][:10], [1,2][5:7]
([1, 2], [])
One would need very good reasons to break this in case of a third-party library.

András

> ________________________________
> From: NumPy-Discussion 
> <numpy-discussion-bounces+tmrsg11=gmail....@python.org> on behalf of Juan 
> Nunez-Iglesias <jni.s...@gmail.com>
> Sent: Friday, February 15, 2019 4:15 AM
> To: Discussion of Numerical Python
> Subject: Re: [Numpy-discussion] [SciPy-User] Why slicing Pandas column and 
> then subtract gives NaN?
>
>
> I don’t have index when I read in the data. I just want to slice two series 
> to the same length, and subtract. That’s it!
>
> I also don’t what numpy methods wrapped within methods. They work, but hard 
> do understand.
>
> How would you do it? In Matlab or R, it’s very simple, one line.
>
>
> Why are you using pandas at all? If you want the Matlab equivalent, use NumPy 
> from the beginning (or as soon as possible). I personally agree with you that 
> pandas is too verbose, which is why I mostly use NumPy for this kind of 
> arithmetic, and reserve pandas for advanced data table type functionality 
> (like groupbys and joining on indices).
>
> As you saw yourself, a.values[1:4] - b.values[0:3] works great. If you read 
> in your data into NumPy from the beginning, it’ll be a[1:4] - b[0:3] just 
> like in Matlab. (Or even better: a[1:] - b[:-1]).
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