It is a truth that, in the case of GP’s, almost always they deal with 
Complaints, Tentative diagnosis or estimation of the Seriousness (good/bad 
feeling), some trial Therapies and some addition investigations/tests,  plus 
finally some time to observe the evolution of the complaints over time; await 
the test results, and after a while get an idea of a possible diagnosis or a 
complaint free patient.

Rarely one consultation resulted in a distinct diagnosis.

The patient population of GP’s is very amorf. There are a lot of haystacks and 
a few needles.

In hospitals it is somewhat different. It is much more finding a diagnosis and 
treatment or proving that there some diagnosis do not apply.
Hospital patient are a highly selected group of patients.


Gerard   Freriks
+31 620347088
  gf...@luna.nl

Kattensingel  20
2801 CA Gouda
the Netherlands

> On 25 Jun 2018, at 14:56, Anastasiou A. <a.anastas...@swansea.ac.uk> wrote:
> 
> Hello Bert and all
> 
> I am a little bit "worried" with "micro-archetypes" the way you describe them.
> 
> I think that what you are probably referring to is "Disease Specific 
> Templates", which I really hope is what we are all working towards :)
> 
> So, archetypes do indeed describe one conceptual quantity, or aspect of a 
> person's healthcare and then a template describes a multidimensional "Point"
> which characterises the patient journey within the disease.
> 
> Consider for example "Total Brain Volume". You can use it to track cognitive 
> decline in AD 
> (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(04)15441-X/abstract)
> and this gives you one "explanatory variable". But, still, there are patients 
> whose brain volume is abnormal (for their age) and they still perform well in 
> other tests, so you need more
> "data points" (a richer template) around the phenomenon to understand it 
> better.
> 
> I think that what you are describing is something like "An automated approach 
> to constructing disease specific 'Minimal Clinical Datasets'".
> 
> Once you have this minimal dataset discovered, THEN you could compose the 
> template or automatically create the archetypes.
> 
> And yes, this CAN be done today, definitely.
> 
> All the best
> Athanasios Anastasiou
> 
> 
> 
> 
> 
> 
> -----Original Message-----
> From: Bert Verhees <bert.verh...@rosa.nl>
> Sent: 25 June 2018 12:31
> To: Anastasiou A. <a.anastas...@swansea.ac.uk>; For openEHR clinical 
> discussions <openehr-clinical@lists.openehr.org>
> Subject: Re: Machine Learning , some thoughts
> 
> On 25-06-18 12:44, Anastasiou A. wrote:
>> The time scales for doing this would be enormous. We can probably work
>> out a lower limit by looking at the lifecycle of archetypes in the current 
>> CKM.
> 
> Thanks, for your answer, I agree with you and others, and already wrote that, 
> that an EHR will not be good enough for machine learning.
> 
> I was too optimistic and to much impressed by some results of machine 
> learning. It will do very good things in healthcare, but only on very 
> specific cases.
> 
> But while writing this
> 
> What would be good, however, an improvement. I suggested to my wife (a GP), 
> and she agreed (partly)
> 
> Classic EHR software only has few datapoints on a screen, and many 
> particularities come into free text, and if the GP is really motivated, maybe 
> he finds some ICPC code.
> 
> Archetypes do not really change this practice. A GP is a busy person.
> 
> What could help is modularity. A GP should be able to add datapoints to his 
> screen. For example, beside all the normal things, the GP sees that there are 
> red eyes, but how can he make this available to the system in a way that it 
> can be found back?
> 
> What about micro-archetypes which describe only one datapoint? And the GP 
> should be able to invoke them by voice. He says "red eyes" and magic happens, 
> there is a datapoint on the screen which offers a possibility to click on a 
> checkbox. Eventually a choice, A bit red, medium red, very red.
> 
> This kind of software does not have to be something for the far future, but 
> can be available already now.
> 
> Also thanks to machine learning, a limited form of NLP (natural language 
> expression (machine learning helping with NLP) can be used, and that was my 
> idea of generating archetypes, last Saturday. A computer could, in some cases 
> of simple datapoints, also even generate micro-archetypes for them, and with 
> templates or container-archetypes, generate evaluation-archetypes
> 
> Maybe, when it is so easy to create datapoints, and store them, maybe then 
> machine learning in diagnostic can come closer, also in some cases for a GP, 
> or machine learning can do suggestion: look to the tongue of the patient, but 
> the fact remains, a good GP needs experience for diagnotics.
> 
> Bert
> 
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