Short of going to 6.0, what else can be done? 
I am in an Enterprise environment, with over 1k users.  Also, does this affect user of Adobe Acrobat 5.0?

NGSSoftware announced it has found a critical security flaw within Adobe Reader 5.1 that could leave users open to having their computers taken over by hackers.

The security firm said the flaw is a data format buffer overflow that could be used by hackers to compromise end-user systems that view specially crafted PDFs. The buffer overflow affects the XML forms data format (XFDF), which is a format for representing forms data and annotations in a PDF document.

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