In case it's of interest, I did a small prototype of how one might
evaluate the sort of criteria, in OWL, that Rachel describes in her
attachment. The post about it is here:
http://lists.w3.org/Archives/Public/public-semweb-lifesci/2007Feb/
0076.html
Subject: counted inclusion + exclusion criteria in OWL
This only addresses the technical issue of how to write the rule. It
doesn't questions of necessary vocabulary, that would be needed to
handle the use case Rachel suggests, just how to put them together
once you have it.
Regards,
Alan
On Aug 27, 2007, at 2:16 PM, Rachel Richesson wrote:
I am attaching some background information on the use case for
discussion on tomorrow at 11 eastern.
I will do my best to lead the call and get feedback on the context
of the use case, and the constructs that might be of most interest.
The attached document describes the idea of querying EMR data for
patients potentially eligible for a given research protocol, and
includes the eligibility criteria from 3 breast cancer studies that
are listed on ClinicalTrials.gov. These examples illustrate the
many constructs (lab, findings, history, procedures, diagnosis,
mutation….) that are found in “eligibility” criteria, which is a
big challenge for the group. I think some discussion and consensus
from the group will help to focus a general use case over the next
few weeks.
I hope that Landen and Bron (from CDISC) can then elaborate on
which CDISC standards might be most applicable here, and perhaps
see how this context relates to an earlier demo on EMR-CDISC
harmonization that was conducted at HIMSS last year.
Thanks,
Rachel
From: [EMAIL PROTECTED] [mailto:public-semweb-
[EMAIL PROTECTED] On Behalf Of Kashyap, Vipul
Sent: Monday, August 27, 2007 9:56 AM
To: public-semweb-lifesci@w3.org; [EMAIL PROTECTED]
Cc: Stanley Huff; Yan Heras; Oniki, Tom (GE Healthcare,
consultant); Joey Coyle; Landen Bain; Bron W. Kisler; Eric Neumann
Subject: [BIONT-DSE] Clinical Observations Interoperability Telcon
August 28th, Tuesday 11:00am - 12:00pm US EDT
Clinical Observations Interoperability Telcon
http://esw.w3.org/topic/HCLS/OntologyTaskForce/BIONTDSEDCM
Date and Time:
August 28th, Tuesday 11:00am – 12:00pm US EDT
Agenda:
1. Presentation and Discussion of Use Case:
Rachel Richesson
2. Presentation of CDISC Standards and Activities
Relevant to this Activity – Landen Bain (CDISC liaison for Healthcare)
Telcon Details:
Phone
+1 617 761 6200, conference 24668 ("BIONT")
IRC
irc://irc.w3.org:6665/hcls
Browser-based IRC client
http://www.w3.org/2001/01/cgi-irc
Feel free to annotate wiki page above with feedback and suggestions.
Cheers,
---Vipul
=======================================
Vipul Kashyap, Ph.D.
Senior Medical Informatician
Clinical Informatics R&D, Partners HealthCare System
Phone: (781)416-9254
Cell: (617)943-7120
http://www.partners.org/cird/AboutUs.asp?cBox=Staff&stAb=vik
To keep up you need the right answers; to get ahead you need the
right questions
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<use case background_W3C Life Sciences_8-27-07.doc>
