At 08:06 AM 9/12/2007, Kavitha Srinivas wrote:

1.  Yes, as Chintan said, in the case where you had explicit
negations in the data (e.g., the lab data rules out the presence of a
certain infectious agent), you clearly want to use open world
reasoning.  However, if someone is not explicitly asserted to be on
some prescription drug, it is fair to assume that they are not taking
the drug (closed world assumption).

Actually, it is dangerous to assume anything if a patient is not explicitly asserted to be taking any particular drug--omissions on drug histories happen all the time... Likewise, making any generalized statements about when open- and closed-world reasoning are appropriate in health care is dangerous--one must be very specific about the context and specific case to assess whether the assumption is valid.


__

Daniel Rubin, MD, MS
Clinical Asst. Professor, Radiology
Research Scientist, Stanford Medical Informatics
Scientific Director, National Center of Biomedical Ontology
MSOB X-215
Stanford, CA 94305
650-725-5693


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