Hi Adrian,

I like your use case...we need better tools for CQI of ontologies...Dan

Adrian Walker wrote:

Hi Dan --

Thanks for your thoughts about this.
You wrote...

If you used a modifier as you suggest below, you would need to modify many of the hundreds of thousands of assertions represented in an ontology like SNOMED.

Actually, it seems that reasoning in executable English over SNOMED and other ontologies could be a useful way of addressing your point that

...it is impossible to create an ontology where everyone agrees with every belief stated.

The executable English can be used to say things like

"according to SNOMED this-type1 and this-type2 are closely related but not everyone agrees"

Users can then get English explanations showing the pertinent entries in SNOMED, and showing who disagrees and why and for what purposes.

How does that sound?

If it's of interest, we can put up an example at [1] that folks can run using browsers. Scalability comes from automatically generating and running SQL from the executable English. The results are still explained in English.

                                        Cheers,  -- Adrian

[1]  Internet Business Logic
A Wiki and SOA Endpoint for Executable Open Vocabulary English over SQL and RDF Online at www.reengineeringllc.com <http://www.reengineeringllc.com> Shared use is free

Adrian Walker
Reengineering





On Mon, Jun 2, 2008 at 9:25 AM, Dan Russler <[EMAIL PROTECTED] <mailto:[EMAIL PROTECTED]>> wrote:

    Hi Adrian,

    Belief is at the core of an ontology, not at the perphery as you
    suggest.

    For example, the belief that "Type 1 Diabetes" and "Type 2
    Diabetes" both have a parent called "Diabetes" is a belief
    instantiated in the SNOMED hierarchy. Of course, this
    representation is frought with physiologic heresy (Type 1 and Type
    2 Diabetes are only related physiologically through a symptom,
    i.e. hyperglycemia, not through common causal phisiologic
    pathways). However, many people will argue that the belief is "true."

    Like most beliefs, one can argue that if the belief is traditional
    or pragmatic instead of strictly valid, it belongs in the ontology
    because it is accepted as "true" by many. However, it is
    impossible to create an ontology where everyone agrees with every
    belief stated. This situation isn't "wrong;" it is simply a fact
    of life in ontology development.

    If you used a modifier as you suggest below, you would need to
    modify many of the hundreds of thousands of assertions represented
    in an ontology like SNOMED.

    Dan


    Adrian Walker wrote:

    Dan --

    You wrote

      How does one bring belief into a model, e.g. realism,
    creationism, etc?

    One way of doing this is to write a layer of knowledge as rules
    in executable English.  The rules can conclude things like
"it is currently the view of US health professionals that..."

       "a possibly useful hypothesis is that...."

    Then, English explanations can show the data and inferential
evidence for the conclusions.
    There's a kind of Wiki for executable English that supports
this. It's online at the site below, and shared use is free. The English vocabulary is open, and so to a large extent is the
    syntax.  Some background is in [1,2].

    Apologies to folks who have seen this before, and thanks for
    comments.

                                                        -- Adrian
    [1] www.reengineeringllc.com/ibldrugdbdemo1.htm
    <http://www.reengineeringllc.com/ibldrugdbdemo1.htm>   (Flash
    video with audio)

[2] www.reengineeringllc.com/A_Wiki_for_Business_Rules_in_Open_Vocabulary_Executable_English.pdf
    
<http://www.reengineeringllc.com/A_Wiki_for_Business_Rules_in_Open_Vocabulary_Executable_English.pdf>

    Internet Business Logic
    A Wiki and SOA Endpoint for Executable Open Vocabulary English
    over SQL
    Online at www.reengineeringllc.com
    <http://www.reengineeringllc.com>    Shared use is free

    Adrian Walker
    Reengineering

    On Tue, Apr 22, 2008 at 5:25 PM, Dan Russler
    <[EMAIL PROTECTED] <mailto:[EMAIL PROTECTED]>> wrote:

        Hi Vipul,

        Peter is right that the term "EAV" is a data schema
        implementation model, even though it maps directly to a
        classic proposition model with subject, predicate, and object
        of the predicate.

        Layer 0 then would be the most abstract layer consisting
        purely of formal propositions. In this layer, some
        propositions may express relationships between one or two
        other propositions, but otherwise, no grouping of
        propositions (classes) nor inheritance are characteristic of
        this layer.

        Peter brings up a good point about the need to deal with
        belief and values in the model. After all, an ontology is
        really a belief system asserted by one or more people. How
        does one bring belief into a model, e.g. realism,
        creationism, etc?

        Regarding your note below on Layer 2...The question is
        whether there are finer layers of distinction between level 1
        and layer 2 (before one actually creates instances that apply
        to individual patients)?

        Dan


        Kashyap, Vipul wrote:

        Dan and Peter,
Based on conversations on this topic, there appears to be
        consensus of the need for multi-layered knowledge
        representation schemes
        for heatlhcare.  Will be great if we could brainstorm and
        come to some sort of consensus on these "layers". Would like
        to propose a
        strawman as enumerated below.
Layer 0 = Entity - Attribute - Value or RDF triple based
        rerpesentations.
        Layer 1 = MetaClasses, e.g., Observation as in HL7/RIM
        Layer 2 = Classes in a Patient Model, Document Models, etc,
        e.g., the class of HbA1c results for a class of Patients.
        Layer 3 = Data that are instances of Classes, e.g., a
        particular HbA1c result for a patient John...
As per your e-mail, you seem to be suggesting that there is
        something in between Layer 1 and Layer 2. However, please
        note that Layer 2 consists
        of classes of assertions in the patient record and not
        instances.
More reespnses are embedded in the e-mail below. <dan> With apologies to Peter in case I misrepresented your
        SOA presentation...Last week, Peter Elkin of Mayo Clinic
        delivered a presentation where he called the HL7 RIM a
        "first order ontology" because of the abstraction level of
        the RIM. He called the models derived from the RIM, e.g.
        analytic models, patient care document models like CDA, etc,
        "second order ontology" because they add a layer of
        concreteness to the abstractions of the RIM, i.e. an object
        with classCode of observation and moodCode of order becomes
        an "observation order object" with neither a classCode nor a
moodCode. [VK] Are there mathematical ways of describing these
        "derivations" for e.g., by using operations such as
        instantiations and generalizations/specializations.
Also, in the above, it's not clear what the semantics of an
        "observation order" object is?
        For e.g., observations and orders are semantically distinct
        concepts, so in some sense an observation order class is
        likely to be unsatisfiable?
The semantics of "moodCode" is not clear in Knowledge
        Representation terms. For instance, do various mood codes
        partition the instances of a class
        into subclasses that are possbily mutually disjoint?
Finally, the coding systems themselves support the
        concreteness of a "third order ontology." For example, the
        SNOMED concept becomes an object itself without a code
        attribute, moodCode attribute, or classCode attribute, e.g.
        a WBC order. />
        [VK] One way of looking at a Snomed code is that it defines
        a class (e.g., blood pressure) of all the instances of blood
        pressure readings which would imply that it belongs to Layer
2 as defined above?
                <dan> see above for the "first order to third order
                model." Your metaclass looks like Peter's "first
                order ontology." However, your "instances" get
                introduced too early...your "instances" point to
                actual medical record assertions, and Peter's model
                suggests that there is more "in between." In
                Peter's model, the actual medical record assertion
                would be an instance of his "third order ontology." />
                [VK] Agree. As per the layering introduced above,
                 Layer 2 would correspond to classes of assetions
                and Layer 3 would correspond to actual instances or
                assertions.

                 <dan> I completely agree that the HL7 RIM is one
                level more "concrete" than the earlier EAV models.
                The EAV model represents the ultimate in
                abstraction, similar to RDF triples. Perhaps Peter
                would be more correct to say that EAV is a "first
                order ontology" and that the HL7 RIM is a "second
                order ontology." />
[VK] Agree: As per layering introduced abiove,
                 The EAV/RDF triples layer could be layer 0, and
                the HL7/RIM layer could be layer 1

Look forward to further brainstorming and feedback
                on this.
Cheers, ---Vipul

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