Philipp Lies <p...@bethgelab.org> added the comment:

a) it's 122GB free RAM (out of 128GB total RAM)

b) when I convert the numpy array to a list it works. So seems to be a problem 
with cPickle and numpy at/from a certain array size

c) $ /usr/bin/time -v python test_np.py 
Traceback (most recent call last):
  File "test_np.py", line 12, in <module>
    A2 = cPickle.load(f2)
MemoryError
Command exited with non-zero status 1
        Command being timed: "python test_np.py"
        User time (seconds): 73.72
        System time (seconds): 4.56
        Percent of CPU this job got: 87%
        Elapsed (wall clock) time (h:mm:ss or m:ss): 1:29.52
        Average shared text size (kbytes): 0
        Average unshared data size (kbytes): 0
        Average stack size (kbytes): 0
        Average total size (kbytes): 0
        Maximum resident set size (kbytes): 7402448
        Average resident set size (kbytes): 0
        Major (requiring I/O) page faults: 0
        Minor (reclaiming a frame) page faults: 726827
        Voluntary context switches: 41043
        Involuntary context switches: 7793
        Swaps: 0
        File system inputs: 3368
        File system outputs: 2180744
        Socket messages sent: 0
        Socket messages received: 0
        Signals delivered: 0
        Page size (bytes): 4096
        Exit status: 1

hth

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