I just share one experience that happened in our department:
The mail server was on one box, and users home directories on
another, and /home was nfs mounted on the mail server. qmail-users
was not set up, and one day, while our sysadm was on vacation, the nfs
server failed---and it was down for 3 days...
Messages were bounced by the thousands since qmail could not find the
mailboxes.
So if you run services on separate boxes, then it is a must to use
qmail-users.
Mate
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Mate Wierdl | Dept. of Math. Sciences | University of Memphis