Perhaps if we had the program name we may be able to help Jack out a bit more, I'd be interested to see what B2 made of it.
The program is an obscure interface app to an ancient gene sequencing machine -
Gene Sequencer 1.1 by Applied Biosystems.
A current copy is $1895, so you can see why we are trying to keep the old version running somehow. Maybe I should just buy a used Q650 for $50 and my problems would be over.
No hope of me trying it on B2 then!
I don't know Basilisk II or SheepShaver but will find out - do they emulate FPU in OSX classic mode?
They are both macOS emulators, being apps they would run in a window on your OSX desktop. Basilisk II emulates a 68k mac, the choice is determined by the rom file you use. Sheepshaver emulates a ppc mac for the most part but draws largely from Basilisk's code.
http://www.users.bigpond.com/pear_computers/ will offer a brief description, howto and screenshot and also the download. I've not tried this port. Its free, you will need a working mac to dump the rom to a file from. Handy for a backup or if you cant spare the extra room for another mac.
Good luck with the Q650 rebirth.
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