Hello Simon and Cyril,Thanks for the reply.You are right Simon. I did not 
notice it too in the literature. The main problem as you said is the storage. 
Actually I developed  the conjugate gradient (CG), quasi-Newton and Newton 
optimization methods for optical tomography and I intended to apply them to the 
CT reconstruction as well. I implemented the Newton's methods (Gauss-Newton and 
Levenberg-Marquardt) in a Jacobian-Free-Newton-Krylov approaches to avoid the 
matrix multiplication of Jacobians (sensitivity). It means we only need to 
store the Jacobian matrix for the these methods (the matrix R that Cyril was 
mentioned), that is still a big matrix for practical problems in CT 
reconstruction. For the quasi-Newton I adapted an L-BFGS algorithm that only 
need the 3 or 8 last iterations of the gradient vector to calculate the Hessian 
matrix. In my case, the L-BFGS and Newton's methods was much faster than the CG 
as you know because of using the second order derivative (hessian matrix). I 
saw in your last paper you implement the conjugate gradient method, so I 
thought it might be easy to extract the gradient vector from CG modules and 
solve the cost function within the quasi-Newton/Newton methods. I will look at 
the codes to see what I can do.Thanks again for the reply.
@Cyril:Please correct me if I am wrong. you mean the output of 
backProjectionFilter is the gradient of defined cost function?
Regards,Vahid 

    On Wednesday, November 2, 2016 2:53 AM, Cyril Mory 
<[email protected]> wrote:
 

  Hi Vahid, Welcome to RTK :) Indeed, there are several iterative methods 
already implemented in RTK, but none of the filters allows you to easily 
extract the gradient of the least squares function there are minimizing. 
 If you need to minimize the classical non-regularized tomographic cost 
function, ie || R f - p ||², with R the forward projection operator, f the 
volume you are looking for, and p the measured projections, my best advice 
would be to copy some part of the pipeline of 
rtkSARTConeBeamReconstructionFilter to get the job done, ie the following part 
(copy-paste this into webgraphviz.com)
 
 digraph SARTConeBeamReconstructionFilter {
 
 Input0 [ label="Input 0 (Volume)"];
 Input0 [shape=Mdiamond];
 Input1 [label="Input 1 (Projections)"];
 Input1 [shape=Mdiamond];
 
 node [shape=box];
 ForwardProject [ label="rtk::ForwardProjectionImageFilter" URL="\ref 
rtk::ForwardProjectionImageFilter"];
 Extract [ label="itk::ExtractImageFilter" URL="\ref itk::ExtractImageFilter"];
 MultiplyByZero [ label="itk::MultiplyImageFilter (by zero)" URL="\ref 
itk::MultiplyImageFilter"];
 AfterExtract [label="", fixedsize="false", width=0, height=0, shape=none];
 Subtract [ label="itk::SubtractImageFilter" URL="\ref 
itk::SubtractImageFilter"];
 MultiplyByLambda [ label="itk::MultiplyImageFilter (by lambda)" URL="\ref 
itk::MultiplyImageFilter"];
 Divide [ label="itk::DivideOrZeroOutImageFilter" URL="\ref 
itk::DivideOrZeroOutImageFilter"];
 GatingWeight [ label="itk::MultiplyImageFilter (by gating weight)" URL="\ref 
itk::MultiplyImageFilter", style=dashed];
 Displaced [ label="rtk::DisplacedDetectorImageFilter" URL="\ref 
rtk::DisplacedDetectorImageFilter"];
 ConstantProjectionStack [ label="rtk::ConstantImageSource" URL="\ref 
rtk::ConstantImageSource"];
 ExtractConstantProjection [ label="itk::ExtractImageFilter" URL="\ref 
itk::ExtractImageFilter"];
 RayBox [ label="rtk::RayBoxIntersectionImageFilter" URL="\ref 
rtk::RayBoxIntersectionImageFilter"];
 ConstantVolume [ label="rtk::ConstantImageSource" URL="\ref 
rtk::ConstantImageSource"];
 BackProjection [ label="rtk::BackProjectionImageFilter" URL="\ref 
rtk::BackProjectionImageFilter"];
 OutofInput0 [label="", fixedsize="false", width=0, height=0, shape=none];
 OutofBP [label="", fixedsize="false", width=0, height=0, shape=none];
 BeforeBP [label="", fixedsize="false", width=0, height=0, shape=none];
 BeforeAdd [label="", fixedsize="false", width=0, height=0, shape=none];
 Input0 -> OutofInput0 [arrowhead=none];
 OutofInput0 -> ForwardProject;
 ConstantVolume -> BeforeBP [arrowhead=none];
 BeforeBP -> BackProjection;
 Extract -> AfterExtract[arrowhead=none];
 AfterExtract -> MultiplyByZero;
 AfterExtract -> Subtract;
 MultiplyByZero -> ForwardProject;
 Input1 -> Extract;
 ForwardProject -> Subtract;
 Subtract -> MultiplyByLambda;
 MultiplyByLambda -> Divide;
 Divide -> GatingWeight;
 GatingWeight -> Displaced;
 ConstantProjectionStack -> ExtractConstantProjection;
 ExtractConstantProjection -> RayBox;
 RayBox -> Divide;
 Displaced -> BackProjection;
 BackProjection -> OutofBP [arrowhead=none];
 }
 
 As you can see, it is a very large part of the SART reconstruction filter, so 
yoiu might be better off just copying the whole 
SARTConeBeamReconstructionFilter and modifying it. 
 
 Of course, you could also look into ITK's cost function class, and see if one 
of the classes inherited from it suits your needs, implement your cost function 
this way, and use ITK's off-the-shelf solvers to minimize it. See the 
inheritance diagram in 
https://itk.org/Doxygen/html/classitk_1_1CostFunctionTemplate.html if you want 
to try this approach.
 
 Best regards,
 Cyril
 
 On 11/01/2016 05:50 PM, vahid ettehadi via Rtk-users wrote:
  
  Hello RTK users and developers, 
  I already implemented the RTK and reconstructed some images with the FDK 
algorithm implemented in RTK. It works well. Thanks to RTK developers.
  Now, I am trying to develop a model-based image reconstruction for our 
cone-beam micro-CT. I see already that some iterative algorithms like ART and 
its modifications and conjugate-gradient (CG) method are implemented in the 
RTK. I want to develop a model-based reconstruction through the 
Newton/quasi-Newton optimizations methods. I was wondering is it possible to 
extract the gradient of least square function from implemented algorithms like 
CG module? Any recommendation will be appreciated.  
  Best Regards, Vahid 
   
  
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