Hi Dan,

I've been following this issue for a while - the good news (see other
threads on this BAI limitation) is the replacement Coordinate Sorted Index
(CSI) from Heng Li which is implemented in htslib (now used internally
by samtools) fixes this limitation.

Which is good news for plant geneticists, people working on
certain marsupials, and any other organisms with long chromosomes.

Regards,

Peter

On Wed, Jul 23, 2014 at 10:58 AM, Dan Bolser <[email protected]> wrote:
> Interesting thread!
>
> I like these comments:
>         "This is twice as long as the longest human chromosome and is
> quite adequate for practical use" - Thomas W. Blackwell
>         "Hopefully 2 Gbp suffices for most species that people are
> interested in." - John Marshall.
>
> As already mentioned, bread wheat, which provides ~20% of all the
> calories consumed by humans globally, has 6 of it's 27 chromosomes
> *assembled* to a length of greater than 537 Mbp [1]...
>
> I won't mention Paris japonica ;-)
>
>
> [1] 
> https://docs.google.com/spreadsheet/ccc?key=0Aqs5UFlky_s6dDlmVVFib3FoSm1tS1JIQzMxY0RVb2c

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