Hi Terry, You should first unzip it (removing the gzip or other compression) then recompress using bgzip (blocked gzip compression).
[Technically you can nest the compression, but it would be pointless] Peter On Thu, Sep 10, 2015 at 9:54 PM, Terry Casstevens <[email protected]> wrote: > Dear Samtools, > > If you use bgzip to zip an already gzipped file, does that result in a > correctly bgzipped file? > > Or should you first ungzip the file and then bgzip? > > Thank you, > > Terry > > ------------------------------------------------------------------------------ > Monitor Your Dynamic Infrastructure at Any Scale With Datadog! > Get real-time metrics from all of your servers, apps and tools > in one place. > SourceForge users - Click here to start your Free Trial of Datadog now! > http://pubads.g.doubleclick.net/gampad/clk?id=241902991&iu=/4140 > _______________________________________________ > Samtools-help mailing list > [email protected] > https://lists.sourceforge.net/lists/listinfo/samtools-help ------------------------------------------------------------------------------ _______________________________________________ Samtools-help mailing list [email protected] https://lists.sourceforge.net/lists/listinfo/samtools-help
