Re: [ccp4bb] Pisa application

2012-08-09 Thread Edwin Pozharski
On 08/08/2012 09:00 AM, Jose Duarte wrote: To my knowledge PISA by itself is not able to do interface prediction To my understanding PISA is not *intended* to do interface prediction

[ccp4bb] Pisa application

2012-08-08 Thread Careina Edgooms
Dear ccp4ers I just wonder whether anybody knows if the PISA software could be used/modified to detect potential interfaces of interaction of different proteins? This would be very useful as a tool to validate protein-protein interactions detected by in vivo methods such as yeast 2 hybrid

Re: [ccp4bb] Pisa application

2012-08-08 Thread Steiner, Roberto
Maybe Nat Protoc.http://www.ncbi.nlm.nih.gov/pubmed?term=Predicting%20protein-protein%20interactions%20on%20a%20proteome%20scale%20by%20matching%20evolutionary%20and%20structural%20similarities%20at%20interfaces%20using%20PRISM# 2011 Aug 11;6(9):1341-54. doi: 10.1038/nprot.2011.367.

Re: [ccp4bb] Pisa application

2012-08-08 Thread Jose Duarte
Hi Careina To my knowledge PISA by itself is not able to do interface prediction. In any case there are a few methods available for protein-protein interface prediction. See for example this nice compilation:

Re: [ccp4bb] Pisa application

2012-08-08 Thread David Waterman
Perhaps IBIS does what you want? http://www.ncbi.nlm.nih.gov/Structure/ibis/ibis.cgi IBIS ... infers/predicts interacting partners and binding sites by homology -- David On 8 August 2012 07:33, Careina Edgooms careinaedgo...@yahoo.com wrote: Dear ccp4ers I just wonder whether anybody

Re: [ccp4bb] Pisa application

2012-08-08 Thread Xun Lu
Hi Careina, I asked the exactly same question in this year's CCP4 summer school @APS, and the answer I got was no ... PISA is not for predicting Cheers, Xun Sent from my iPad On Aug 8, 2012, at 2:33 AM, Careina Edgooms careinaedgo...@yahoo.com wrote: Dear ccp4ers I just