On 08/08/2012 09:00 AM, Jose Duarte wrote:
To my knowledge PISA by itself is not able to do interface prediction
To my understanding PISA is not *intended* to do interface prediction
Dear ccp4ers
I just wonder whether anybody knows if the PISA software could be used/modified
to detect potential interfaces of interaction of different proteins? This would
be very useful as a tool to validate protein-protein interactions detected by
in vivo methods such as yeast 2 hybrid
Maybe
Nat
Protoc.http://www.ncbi.nlm.nih.gov/pubmed?term=Predicting%20protein-protein%20interactions%20on%20a%20proteome%20scale%20by%20matching%20evolutionary%20and%20structural%20similarities%20at%20interfaces%20using%20PRISM#
2011 Aug 11;6(9):1341-54. doi: 10.1038/nprot.2011.367.
Hi Careina
To my knowledge PISA by itself is not able to do interface prediction.
In any case there are a few methods available for protein-protein
interface prediction. See for example this nice compilation:
Perhaps IBIS does what you want?
http://www.ncbi.nlm.nih.gov/Structure/ibis/ibis.cgi
IBIS ... infers/predicts interacting partners and binding sites by homology
-- David
On 8 August 2012 07:33, Careina Edgooms careinaedgo...@yahoo.com wrote:
Dear ccp4ers
I just wonder whether anybody
Hi Careina,
I asked the exactly same question in this year's CCP4 summer school @APS,
and the answer I got was no ... PISA is not for predicting
Cheers,
Xun
Sent from my iPad
On Aug 8, 2012, at 2:33 AM, Careina Edgooms careinaedgo...@yahoo.com wrote:
Dear ccp4ers
I just