[ccp4bb] postdoctoral position in structural biology of the tubulin code
A postdoctoral fellowship opportunity is available in the Cell Biology and Biophysics Unit headed by Dr. Antonina Roll-Mecak to work on the tubulin code using in vitro reconstitution and superresolution microscopy to capture the dynamic behavior of cytoskeletal complexes coupled with cryo-EM, single particle, and tomography to obtain structural information in vitro and in cells. For more information please visit: https://research.ninds.nih.gov/roll-mecak-lab*. * We are looking for Ph.D. graduates with a strong record of accomplishments and expertise in biochemistry and cell biology. Expertise with cryo-EM is not needed. We are happy to teach! The NIH has an outstanding cell and structural biology community, and the lab has regular access to state-of-the-art resources such as a Chameleon, Krios with K3 camera, Glacios, TIRF and lattice sheet microscopes, as well as cryo-FIB SEM. Please send your CV, a one-page research experience summary and contact information of three references to anton...@nih.gov Please write “Tubulin code fellowship” in the subject header. To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
[ccp4bb] Postdoctoral Position Available
Hi All, This post is to bring your attention to a postdoctoral position currently available in the Structural Chemistry group, part of the Institute for Applied Cancer Science (IACS) within the Therapeutics Discovery Division of MD Anderson Cancer Center. The highly collaborative teams within IACS are focused on discovering and developing the next generation of small-molecule therapeutics targeting unmet medical needs in oncology and neurodegeneration. This is a unique opportunity to learn how structural biology contributes to the development of novel therapeutics by participating in the drug discovery process as a team member. The postdoctoral researcher will have the opportunity to work in a project-driven environment with a multi-disciplinary team of scientists from several functional groups (eg. in vitro pharmacology, medicinal and computational chemistry) all within a highly respected academic and clinical setting. We are seeking an individual with a background in structural biology, including protein expression and purification, protein crystallization, and X-ray crystallography structure determination. Experience with biophysical techniques to measure binding interactions (eg. ITC, SPR, MST), fragment based drug discovery and/or structure determination of membrane proteins is not required, but would be advantageous. We want a motivated individual to join us in our quest to discover, develop, and deliver more effective treatments to our patients. Interested individuals should send an introductory email and CV to therapeut...@mdanderson.org To apply visit the link below: https://www.mdanderson.org/about-md-anderson/careers/open-trainee-positions.html Applied Cancer Science - Req #: 600140-202204261644 To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
Re: [ccp4bb] X-ray crystallography defense questions
Dear Jessica, The opening question from your external examiner I expect to be “Your studentship funder is interested in your training and competence in research methods, your university however, in deciding to award your degree, has to know what your contribution to knowledge is?” PhD theses require an abstract but what you need to answer that question is a shorter synopsis. A synopsis can be quite tricky to get right whilst being succinct. I realise I have not answered your precise question, on Xray crystallography questions that may arise. So, on that point, the topical question seems to be “What is your view on being able to predict what you have found out by Xray crystallography? Best wishes, John Emeritus Professor John R Helliwell DSc > On 14 Jun 2022, at 16:58, Jessica Besaw wrote: > > > Hello CCP4! > > I am preparing for my PhD defense on X-ray crystallography of membrane > proteins. > > So my ask from you folks is: What X-ray crystallography questions would you > ask in a PhD defense? > > All questions - easy, tough, tricky - are welcome. > > Thank you kindly, > > Jessica Besaw > > > > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/