[ccp4bb] Postdoctoral position, Institut Européen de Chimie et Biologie, Bordeaux, France
Dear all, A One 2-year postdoctoral position funded by the ANR (Agence Nationale pour la Recherche) is available in the « structure and function of bacterial nanomachines » group at Institut Européen de Chimie et Biologie in Pessac (near Bordeaux). The project is dedicated to the study of protein complexes involved in the assembly of the /Helicobacter pylori/type IV secretion system. The selected candidate will be in charge in the purification and structure determination of the complexes by X-ray crystallography or Cryo-EM in collaboration with the group of Dr. Laurent Terradot (IBCP, Lyon, France). She/he will use a wide range of approaches /in vitro/ and /in vivo/ (including molecular biology, biochemistry, microbiology and structural biology techniques such as single particule CryoEM and Cryo-tomography). Interested candidates should have recently obtained a Ph.D. in molecular/structural biology and should have relevant research publications in this field. Candidates should be self-motivated and have recently obtained a PhD degree in Biochemistry, Structural Biology or related disciplines. Candidates should also have practical knowledge of protein biochemistry and experience in protein complex purification and characterization. Experience in X-ray or Cryo-EM data processing would be an asset but is not mandatory The position will be available in 2021. The starting date will be decided in agreement with the selected candidate, preferably during the first trimester of 2022. *Contact*: *Applications in the form of a CV, publication list, a summary of research activities (2 pages max) and contact details of two referees, should be sent by Email to Rémi Fronzes (**r.fron...@iecb.u-bordeaux.fr)* <mailto:r.fron...@iecb.u-bordeaux.fr)>*or Laurent Terradot (laurent.terra...@ibcp.fr) * *Selected candidates will be individually interviewed and a final decision will be made before the end of January 2022.* -- Laurent Terradot Director of Research CNRS Principal Investigator lab web page:http://perso.ibcp.fr/laurent.terradot/terradot_lab/Terradot_Lab.html Structural Biology of Bacterial Macromolecular Complexes Institut de Biologie et Chimie des Protéines, UMR 5086 CNRS-Université Lyon 1 7 passage du vercors, 69007 Lyon Cedex, France Cell Phone +33(0)6 33 69 73 14 Phone +33(0)4 72 72 26 52 Fax +33(0)4 72 72 26 04 To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
[ccp4bb] 48 months PhD fellowship in Structural Microbiology available in Lyon, France
Dear ccp4bb, dear colleagues, A 4-years phD fellowship for (and only for) a Chinese citizen is available in my laboratory in the frame of the France-China collaboration agreement with the University of Lyon. The PhD project is to study the structure and function of the type IV secretion system of Helicobacter pylori (See Bergé et al., 2017; Koelblen et al., 2017). Protein and complexes involved in substrate translocation will be purified and their structures will be determined by X-ray crystallography and/or Cryo-EM. (detailed here https://www.universite-lyon.fr/medias/fichier/ediss-l-terradot-en-_1608113877579-pdf?ID_FICHE=88505) The applicant must hold a Master's degree in Biochemistry and have proven experience in protein purification. The laboratory languages are english and french and the candidate must be fluent in one of them. To apply, send a cover letter, 1-2 reference letters and a detailed CV to Dr. Laurent Terradot (laurent.terra...@ibcp.fr) Details on how to apply can be found here and the deadline for application is February the 10th https://www.universite-lyon.fr/research/phd/phd-csc/csc-phd-scholarships-candidates-applying-to-a-phd-program-at-the-universite-de-lyon-10386.kjsp?RH=1543929774954 -- Laurent Terradot Director of Research CNRS Principal Investigator lab web page: http://perso.ibcp.fr/laurent.terradot/terradot_lab/Terradot_Lab.html Structural Biology of Bacterial Macromolecular Complexes IBCP, UMR 5086 CNRS-Université Lyon 1 7 passage du vercors, F-69367, France Cell Phone +33(0)6 33 69 73 14 Phone +33(0)4 72 72 26 52 Fax +33(0)4 72 72 26 04 To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
[ccp4bb] Post-doctoral position in IBCP, Lyon- France
Dear all, *A 2 years postdoctoral position funded by the Agence National de la Recherche (ANR) *is available in the group of Dr. Laurent Terradot (@LaurentTerradot ) in the Unit Molecular Microbiology and Structural Biochemistry (MMSB) of the Institut de Biologie et Chimie des Protéines (IBCP, CNRS-University of Lyon), Lyon, France. We are interested in structure function of protein-protein complexes involved in Helicobacter pylori pathogenesis. This bacterium is a major human pathogen that can cause human diseases such as ulcers and gastric cancers. The position is dedicated to the understanding of Helicobacter pylori Type IV secretion system by the determination of several protein-protein complexes by X-ray crystallography or Cryo-EM. Preliminary data are already available for several protein samples. For more information on the project see Koelblen et al., 2017; Bergé and Terradot, 2017; Bergé, Wakmsan and Terradot, 2017, Bats et al., 2018; Zhao et al., 2019. The IBCP (www.ibcp.fr) is well equipped for cell biology, molecular biology and biochemistry and Structural Biology and belongs to a larger campus (Lyon Biopole; Center for Infectiology), giving access to state-of-the-art core facilities in areas. The group has regular access to synchrotron beam time and Cryo-EM. Lyon is a vibrant, historical French city and is a world-excellence center in infectiology. Working language of the laboratory is English. We are looking for enthusiastic and self-motivated individuals with a strong background in protein purification and Structural biology. Experience in the study of complexes would be a plus. Knowledge in Macromolecular Crystallography and/or Cryo-EM would be considered an advantage but is not mandatory. Proposed starting date: *February 2020 * Salary is according to the CNRS french guidelines and should be between 2500-3200 euros gross monthly according to experience. *Interested candidates must apply online*on the CNRS website: https://emploi.cnrs.fr/Offres.aspx with a CV, reference letter(s) and a short summary of your experience/motivation ** Laurent Terradot -- Laurent Terradot Director of Research CNRS Principal Investigator lab web page: http://perso.ibcp.fr/laurent.terradot/terradot_lab/Terradot_Lab.html Structural Biology of Bacterial Macromolecular Complexes IBCP, UMR 5086 CNRS-Université Lyon 1 7 passage du vercors, F-69367, France Cell Phone +33(0)6 33 69 73 14 Phone +33(0)4 72 72 26 52 Fax +33(0)4 72 72 26 04 To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1
[ccp4bb] Post-doctoral position in Lyon, France
Post-doctoral position in Structural Biology of Bacterial Pathogenesis at the IBCP (Lyon, France) ** *A FINOVI (http://www.finovi.org) funded postdoctoral position *is available immediately in the group of Laurent Terradot at the Institut de Biologie et Chimie des Protéines (IBCP), Lyon, (http://www.ibcp.fr). We are interested in the structure/function of protein complexes involved in bacterial pathogenesis. The funded position will aim to solve the structures of type IV secretion system effectors and understand their mode(s) of action (see Tosi /et al/., Febs L, 2009; Jimenez-Soto /et al/., PloS Pathogens, 2009; Kaplan-Türköz et al., PNAS, 2012). The project is a collaboration between our laboratory and team of P. Doublet at the University of Lyon 1. The IBCP is well equipped for Molecular Biology, Biochemistry, Bioinformatics and Structural Biology and belongs to a larger campus (UMS3444/US8, Lyon Biopole; Center for Infectiology), giving access to state-of-the-art core facilities, including crystallogenesis and biophysics platforms. The group has regular access to synchrotron beam time and is ideally located one hour from the European Synchrotron ESRF. Lyon is a vibrant, historical French city and is a world-excellence center in Infectiology. We are looking for enthusiastic and self-motivated individuals with a strong background in X-ray crystallography, model building and refinement. Successful experience in protein purification for structural studies is required. Experience in protein-protein interactions (Biacore, ITC) and/or study of large complexes would be a plus. Working language of the laboratory is English. Starting date: *As soon as possible*. Salary is according to the CNRS french guidelines. Please send a cover letter, your CV and reference letters as a single PDF file to: *laurent.terra...@ibcp.fr mailto:laurent.terra...@ibcp.fr* ** *Address:* ** *Laurent Terradot* ** /Institut de Biologie et Chimie des Protéines/ /ATIP-CNRS Group Structural Biology of Bacterial Macromolecular Complexes/ /UMR 5086 CNRS Université de Lyon/ /7, passage du Vercors/ /69367 Lyon cedex 07 FRANCE/ //tel: +33 (0) 472 72 2652 Fax: +33 (0) 472 72 2604 -- Laurent Terradot ATIP-Avenir Group Leader Structural Biology of Bacterial Macromolecular Complexes Université Lyon 1, Univ Lyon, France; CNRS, UMR 5086 ; Bases Moléculaires et Structurales des Systèmes Infectieux, IBCP 7 passage du vercors, F-69367, France Phone +33(0)4 72 72 26 52 Fax +33(0)4 72 72 26 04
[ccp4bb] Post-doctoral position in Structural Biology in Lyon, France
*A post-doctoral position *is available immediately in the group of Laurent Terradot at the Institut de Biologie et Chimie des Protéines (IBCP), Lyon, (http://www.ibcp.fr). We are interested in the structure/function of protein complexes involved in /Helicobacter pylori /pathogenesis. This bacteria is a major pathogen that causes human diseases such as ulcers and gastric cancers. Several projects are available in our laboratory to study 1) virulence factors/receptor interactions (see Tosi /et al/., Febs L, 2009; Angelini /et al/., Febs Journal, 2009; Jimenez-Soto /et al/., PloS Pathogens, 2009) and 2) DNA replication regulation (see Natrajan et al., Mol. Microbiology, 2007; Natrajan et al., PNAS, 2009). Part of the work will be carried out with National and International collaborations. The IBCP is well equipped for Molecular Biology, Biochemistry, Bioinformatics and Structural Biology and belongs to a larger campus (Lyon Biopole; Center for Infectiology), giving access to state-of-the-art core facilities. The group has regular access to synchrotron beam time and is ideally located one hour from the European Synchrotron ESRF. Lyon is a vibrant, historical French city and is a world-excellence center in Infectiology. We are looking for enthusiastic and self-motivated individuals with a strong background in protein purification for structural studies. Experience in protein-protein interactions (Biacore, ITC, etc...) and/or study of large complexes would be a plus. Knowledge in Macromolecular Crystallography would be considered an advantage but is not mandatory as training can be provided. Working language of the laboratory is English. Starting date: *As soon as possible*. Salary is according to the CNRS french guidelines and will depend on experience. Please send a cover letter, your CV and one (or more) reference letter as a single PDF file to: *laurent.terra...@ibcp.fr mailto:laurent.terra...@ibcp.fr * Deadline: May the 1st, 2010. ** * * -- Laurent Terradot Institut de Biologie et Chimie des proteines ATIP-CNRS Group Structural Biology of Bacterial Macromolecular Complexes UMR 5086 CNRS Université de Lyon 7, passage du Vercors 69367 Lyon cedex 07 FRANCE tel: +33 (0) 472 72 2652 Fax: +33 (0) 472 72 2604
