[ccp4bb] A Postdoctoral Scholar position opening

2017-11-30 Thread Oleg Tsodikov
A Postdoctoral Scholar position is available in the laboratory of Dr.
Oleg Tsodikov
at the University of Kentucky (USA), Department of Pharmaceutical Sciences,
to study mechanisms involved in bacterial drug resistance. We use a
combination of structural biology (X-ray crystallography), enzymology,
biophysical chemistry and computation. We seek a highly motivated
individual with a Ph.D. degree and with experience in protein purification
and enzymatic assays.

Experience in macromolecular crystallography is a plus, but not a requirement.

Applicants should email Dr. Oleg Tsodikov at ovts...@uky.edu. Please,
include a CV and contact information for 3 references.


[ccp4bb] An open postdoctoral position in structural enzymology at the University of Kentucky

2017-08-15 Thread Oleg Tsodikov
A postdoctoral position is available in the laboratory of Dr.
Oleg Tsodikov at the University of Kentucky, Department of
Pharmaceutical Sciences starting in early 2018 or later, to perform
structural, biochemical and biophysical studies of proteins involved in
bacterial drug resistance. We seek highly motivated individuals with a
Ph.D. degree and with experience in protein purification and
enzymatic assays.

Applicants should email Dr. Oleg Tsodikov at ovts...@uky.edu.
Please, include a CV and contact information for 3 references.


[ccp4bb] A postdoctoral position opening in structural biology at the University of Kentucky

2014-12-25 Thread Oleg Tsodikov
Postdoctoral positions are is available in the laboratory of Dr.
Oleg Tsodikov at the University of Kentucky, Department of
Pharmaceutical Sciences (
http://pharmacy.mc.uky.edu/faculty/tsodikov/index.php) starting
immediately, in the areas of bacterial resistance to antibiotics and
mechanisms of oncogenic transcriptional regulators. These projects are
integral parts of ongoing highly collaborative translational
bench-to-bedside drug discovery and development efforts. Our group
uses a combination
of structural biology, enzymology, biophysics and computation to tackle
problems. We seek highly motivated individuals with a Ph.D. degree and with
strong documented experience in enzymology, including protein purification.

Applicants should email Dr. Tsodikov at oleg.tsodi...@uky.edu.
Please, include a CV and contact information for 3 references.


Oleg Tsodikov
Associate Professor of Pharmaceutical Sciences


[ccp4bb] Refmac bond restraints across special positions?

2014-03-12 Thread Oleg Tsodikov
Colleagues,

We have determined a structure of a palindromic DNA molecule, in which one
half of the DNA is in the asymmetric unit. Is there a way to tell REFMAC
that there are covalent bonds across asymmetric units? Without such LINK
records in the PDB file, REFMAC treats this as a non-covalent interaction
and pushes the two DNA halfs apart. The data are at a fairly high
resolution, which helps, but the repulsion is still there.

Any advice would be greatly appreciated! I imagine this situation is quite
rare in macromolecular crystallography.

Oleg
-- 
Oleg Tsodikov, Ph.D.
Associate Professor of Pharmaceutical Sciences
University of Kentucky College of Pharmacy
Department of Pharmaceutical Sciences
BioPharm Bldg, Room 425
789 S. Limestone
Lexington, KY 40536


[ccp4bb] Postdoctoral Scholar position in Structural Biology

2014-02-28 Thread Oleg Tsodikov
A Postdoctoral Scholar position in structural biology is available in the
laboratory of Dr. Oleg Tsodikov at the Department of Pharmaceutical
Sciences at the University of Kentucky (
http://pharmacy.mc.uky.edu/faculty/tsodikov/index.phphttps://exchange.uky.edu/owa/14.3.123.3/scripts/premium/redir.aspx?C=TX275oKkoU6Enznt62KjfGP-lCtACNEIxrb0lHJcH9mYcts07gVsq_ODyNKeLkzCv7msqM9-fwo.URL=http%3a%2f%2fpharmacy.mc.uky.edu%2ffaculty%2ftsodikov%2findex.php),
starting immediately to study oncogenic transcription factors and their
interactions with DNA, other proteins and small molecule ligands. We seek
highly motivated individuals with a Ph.D. degree and with experience in
X-ray crystallography.

Applicants should email Dr. Tsodikov at
oleg.tsodi...@uky.eduhttps://exchange.uky.edu/owa/14.3.123.3/scripts/premium/redir.aspx?C=TX275oKkoU6Enznt62KjfGP-lCtACNEIxrb0lHJcH9mYcts07gVsq_ODyNKeLkzCv7msqM9-fwo.URL=mailto%3aoleg.tsodikov%40uky.edu.
Please, include a CV and contact information for 3 references.


-- 
Oleg Tsodikov, Ph.D.
Associate Professor of Pharmaceutical Sciences
University of Kentucky College of Pharmacy
Department of Pharmaceutical Sciences
BioPharm Bldg, Room 425
789 S. Limestone
Lexington, KY 40536


[ccp4bb] A Postdoctoral Scholar position in structural biology

2013-09-04 Thread Oleg Tsodikov
*A Postdoctoral Scholar position in structural biology at the University of
Kentucky*



A Postdoctoral Scholar position in structural biology is available in the
laboratory of Dr. Oleg Tsodikov at the Department of Pharmaceutical
Sciences at the University of Kentucky (
http://pharmacy.mc.uky.edu/faculty/tsodikov/index.php), starting
immediately to study transcription factors involved in oncogenesis and
their interactions with DNA. We seek highly motivated individuals with a
Ph.D. degree and with experience in protein purification and enzymatic
assays. Prior structural biology experience is an asset, but not a
requirement.

Applicants should email Dr. Tsodikov at oleg.tsodi...@uky.edu. Please,
include a CV and contact information for 3 references.