[ccp4bb] Postdoc position available

2024-09-12 Thread Gabriel Demo
Dear all,

We seek a talented individual to fill a postdoctoral position (at the Central 
European Institute of Technology (CEITEC), Masaryk University Brno, Czech 
Republic.) with expertise in the field of cryo-electron microscopy and 
translation regulation. Ideal candidates should possess a solid foundation in 
biochemistry or structural biology, particularly in single-particle 
cryo-electron microscopy or protein crystallography.

For more details, please visit our website 
https://demolab.ceitec.cz/
 and the postdoctoral position offer 
https://www.ceitec.eu/postdoctoral-fellow-in-the-research-group-of-gabriel-demo/j500.

To apply, please submit your CV, along with contact information for three 
referees, and a brief motivational letter to recruitm...@ceitec.muni.cz. The 
deadline for applications is September 30th, 2024.

Best regards,

--



Mgr. Gabriel Demo, PhD. | CEITEC MU

Junior Group Leader



tel: +420 549 49 7827

e-mail: gabriel.d...@ceitec.muni.cz

web: www.ceitec.cz



Masarykova univerzita

Central European Institute of Technology

Kamenice 5, 625 00 Brno

Kancelář A35/1S155



#CEITECScience

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[ccp4bb] Postdoc position available at LNBR/CNPEM

2024-05-29 Thread Mario Tyago Murakami
Postdoctoral position available in carbohydrate enzymology and structural 
biology
We are looking for candidates who are interested in exploring the microbial 
dark matter from Brazilian mega biodiversity aiming at elucidating novel 
mechanisms involved in carbohydrate breakdown and modification using an 
interdisciplinary approach including integrated omics, carbohydrate enzymology, 
site-directed mutagenesis, X-ray crystallography, Cryo-EM, mass spectrometry 
and computational biology.
Application deadline June 21, 2024; Expected starting date August 1st, 2024.

Mário Murakami
mario.murak...@lnbr.cnpem.br



Mário T. Murakami

Scientific Director

Brazilian Biorenewables National Laboratory (LNBR)

National Center for Research in Energy and Materials (CNPEM)

Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, São Paulo, Brasil. CEP: 
13083-100

(19) 3518-3198 | (19) 99654 3909 | 
mario.murak...@lnbr.cnpem.br

www.lnbr.cnpem.br / 
www.cnpem.br




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[ccp4bb] Postdoc position available

2024-03-07 Thread Gabriel Demo
Dear all,

We seek a talented individual to fill a postdoctoral position (at the Central 
European Institute of Technology (CEITEC), Masaryk University Brno, Czech 
Republic.) with expertise in the field of cryo-electron microscopy and 
translation regulation. Ideal candidates should possess a solid foundation in 
biochemistry or structural biology, particularly in single-particle 
cryo-electron microscopy or protein crystallography.

For more details, please visit our website 
https://demolab.ceitec.cz/
 and the postdoctoral position offer 
https://www.ceitec.eu/postdoctoral-fellow-in-the-research-group-of-gabriel-demo/j500.

To apply, please submit your CV, along with contact information for three 
referees, and a brief motivational letter to recruitm...@ceitec.muni.cz. The 
deadline for applications is June 30th, 2024.

Best regards,

--



Mgr. Gabriel Demo, PhD. | CEITEC MU

Junior Group Leader



tel: +420 549 49 7827

e-mail: gabriel.d...@ceitec.muni.cz

web: www.ceitec.cz



Masarykova univerzita

Central European Institute of Technology

Kamenice 5, 625 00 Brno

Kancelář A35/1S155



#CEITECScience

facebook
 | 
twitter
 | 
instagram
 | 
linkedin
 | 
youtube



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[ccp4bb] PostDoc position available

2023-10-31 Thread Wei Zhang
Dear all,

A NIH-funded postdoctoral research associate position is available at Dr.
Wei Zhang's laboratory at the University of Minnesota (Minneapolis,
Minnesota, USA). The successful candidate will study enveloped
virus assembly and entry using cryo-EM, single particle reconstruction,
cryo-ET, subtomogram averaging, and related biochemical and biophysical
methods. The position offers opportunities to work with outstanding
researchers through established and successful collaborations.



*Required Qualifications*. Candidates should have: (1) a Ph.D. in virology,
structural biology, biophysics, or related field; (2) published in
international peer-reviewed journals.



*Preferred Qualifications*. Experience protein structure determination and
strong computation skills.



We welcome all applicants who have a passion for research and the drive to
learn and contribute to the field.  Interested candidates should submit a
pdf with cover letter, CV and names/info for three references to Dr. Zhang
at zhang...@umn.edu.


Best regards,


Wei Zhang



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[ccp4bb] PostDoc position available

2023-10-21 Thread Birte Hoecker
Dear all,

sorry to all who are not currently looking for a PostDoc position.


Postdoctoral opportunity – Structural Biology / Protein Engineering

An ERC-funded postdoctoral position is available in the lab of Birte Höcker at 
Bayreuth University, Germany. Within the project we apply structural biology, 
protein engineering and computational protein design to construct new protein 
motors. We are seeking a motivated personality with experience in protein 
biochemistry and structural biology interested in working in an 
interdisciplinary and international team. The position requires a PhD in 
biochemistry, biotechnology, structural biology, or a related field. Experience 
with structure determination, enzymology, computational protein design or 
directed evolution are all welcome.

The overall project is in collaboration with partners from Lund University, 
Sweden and UNSW in Sydney, Australia. Our own group is situated in the 
biochemistry department of the University of Bayreuth. The department is 
well-equipped in terms of structural biology, biophysics, and computing. 
Bayreuth is a beautiful city in the north of Bavaria in between Fränkischer 
Schweiz and the Fichtelgebirge with great outdoor opportunities. Interested 
candidates should contact me directly for more details on the project. A full 
application should include a CV, short description of prior experience, 
motivation and contact details of references.

Birte Höcker (birte.hoec...@uni-bayreuth.de 
) 




Birte Höcker, Prof. Dr. 
Biochemie, NWIII
Universität Bayreuth
95440 Bayreuth, Germany
www.proteindesign.uni-bayreuth.de






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[ccp4bb] Postdoc position available: Structural Biology of RNA-protein complexes

2023-01-30 Thread Yunsun Nam
A postdoctoral research position is available in the laboratory of Yunsun Nam 
Ph.D., in the Department of Biochemistry at the University of Texas 
Southwestern Medical Center, to study the mechanisms underlying RNA-protein 
complexes important for gene regulation. Our laboratory works on exciting 
projects dissecting how chemistry and structure contribute to assembling 
specific RNA-protein complex architectures important for normal gene 
expression, using structural biology and biochemistry. The RNA-protein 
complexes we study are relevant for normal development as well as diseases. As 
we unravel how dysregulated RNA-protein complexes derail gene expression and 
cause cancer, we use our mechanistic insights to identify novel therapeutic 
avenues.

Postdoctoral scholars will have opportunities to learn the newest methods in 
protein and nucleic acid biochemistry and biophysics, in addition to working in 
an exciting, fast-evolving field in biomedical sciences. We use various 
approaches, including cryo-electron microscopy (cryo-EM), X-ray 
crystallography, NMR spectroscopy, molecular biology, nucleic acid and protein 
biochemistry, genomics with next-generation sequencing, high-throughput 
screening for drug discovery, and cancer cell biology. The postdoctoral fellow 
will have ready access to the top-of-the-line equipment and resources necessary 
for the above approaches. For cryo-EM, we have ready access to four microscopes 
on our campus: two Titan Krios, one Glacios, and one Talos Arctica. Information 
on our postdoctoral training program, benefits, and a virtual tour can be found 
at http://www.utsouthwestern.edu/postdocs.

Candidates must hold a Ph.D. and/or M.D. degree. Experience in biochemistry and 
structural biology leading to publication in peer-reviewed journals is 
recommended. Interested individuals should send a CV, a statement of interest, 
and a list of three references as a single pdf file to: 
yunsun@utsouthwestern.edu (Lab Website: www.ynamlab.org).

UT Southwestern Medical Center is committed to an educational and working 
environment that provides equal opportunity to all members of the University 
community.  As an equal opportunity employer, UT Southwestern prohibits 
unlawful discrimination, including discrimination on the basis of race, color, 
religion, national origin, sex, sexual orientation, gender identity, gender 
expression, age, disability, genetic information, citizenship status, or 
veteran status.  



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[ccp4bb] Postdoc position available at Diamond as part of the NIH funded ASAP consortium developing antivirals

2023-01-10 Thread Walsh, Martin (DLSLtd,RAL,LSCI)
Dear All
following on from the success of our massive fragment based drug discovery 
effort targeting the main protease of SARS-CoV-2 which led to the COVID 
moonshot initiative (https://postera.ai/moonshot/ ) and has led to things 
working out far more than we would have ever imagined in such a short time 
period (see https://dndi.org/research-development/portfolio/covid-moonshot/ ) 
…..

we now have an exciting opportunity to join our team which is part of one of 
the NIH/NIAID's AViDD 
centers,
 namely AI-driven Structure-enabled Antiviral Platform 
(ASAP)

–So if you are interested in a structure-based drug discovery focused post-doc 
targeting emerging pathogens of concern then look no further – come and join us 
at Diamond – more details here:

https://vacancies.diamond.ac.uk/vacancy/post-doctoral-research-associate-aidriven-structureenabled-antiviral-platform-511397.html
closing date: 5th February 2023

don’t hesitate to contact me directly for more details/questions about the post

Martin
--
Martin A. Walsh (He/Him/His),
Deputy Director Life Sciences &
Group Leader at the Research Complex at Harwell,
Diamond Light Source,
Harwell Science & Innovation Campus,
Didcot OX11 0DE,
UK
T:+44 1235 778518
E:martin.wa...@diamond.ac.uk


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[ccp4bb] postdoc position available in the lab of Prof. Eddy Arnold (Rutgers University, NJ, USA)

2022-07-11 Thread F. Xavier Ruiz
Dear All,

We have an immediate opening for a skilled post-doctoral researcher in the 
laboratory of Prof. Eddy Arnold at Rutgers University (NJ, USA).
The aim of the project is to study the structure and function of human viral 
proteins (and polyproteins), including from polymerases from HIV-1, SARS-CoV-2 
and other RNA viruses with pandemic potential, through cryo-electron microscopy 
(and also X-ray crystallography). The funding comes from the recently awarded 
AViDD centers 
(https://cabm.rutgers.edu/news/new-nih-awards-eddy-arnold-lab-antiviral-drug-discovery)
 and the HIVE center (http://www.hivecenter.net/).

For more information about the position, please see the full advert: 
https://jobs.rutgers.edu/postings/166341

Interested candidates should apply via the above link. For informal inquiries, 
please feel free to contact me directly.

Best wishes, 

Xavi

F. Xavier Ruiz
Assistant Research Professor
Arnold Laboratory
Center for Advanced Biotechnology and Medicine
Rutgers University

Websites: https://cabm.rutgers.edu/person/francesc-x-xavi-ruiz-figueras
   https://publons.com/researcher/1525897/francesc-xavier-ruiz/



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[ccp4bb] Postdoc position available at the University of Chicago

2022-02-12 Thread Minglei Zhao
Dear All,
A postdoctoral position is available in my lab in the Department of 
Biochemistry and Molecular Biology at the University of Chicago. Research in 
the lab is centered at the interface of chemistry and biology. We are 
interested in the structure and function of molecular machines involved in 
post-transcriptional and post-translational modifications, such as mRNA 
methylation and protein ubiquitination. Structural biology techniques including 
X-ray crystallography and cryo-electron microscopy are used in the lab. For 
more information and recent publications, please visit our website 
(https://zhaolab.uchicago.edu ).

UChicago has a long tradition of research excellence and a stimulating 
environment. It also has a state-of-the-art cryo-EM facility housing a Titan 
Krios, an incoming Glacios, an Aquilos cryo-FIB and a VolumeScope. In addition, 
UChicago operates Argonne National Laboratory for the Department of Energy, 
which is home to the Advanced Photon Source (APS), one of the world’s largest 
synchrotron facilities.

The position will be fully funded by UChicago and NIH under NIH guidelines. 
Qualified applicants should have or expect a Ph.D. degree in molecular biology 
or related fields, be highly self-motivated, and demonstrate ability for 
rigorous scientific research with publications in peer-reviewed journals. The 
candidate is expected to have expertise in molecular biology and a strong 
ability to learn new techniques. Previous experience in structural biology is 
desired but not required. Experience in chemical biology, protein engineering, 
cell biology and protein biochemistry is a plus.

Please send a CV and contact information of three references to: 
mlz...@uchicago.edu .

Thank you for your attention.



Best regards,

Minglei


Minglei Zhao, Ph.D.
Assistant Professor
Department of Biochemistry and Molecular Biology
University of Chicago
GCIS W204  
929 E. 57th Street 
Chicago, IL 60637
Tel: (773) 834-3293
https://zhaolab.uchicago.edu 



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[ccp4bb] postdoc position available in the lab of Prof. Eddy Arnold (Rutgers University, NJ, USA)

2021-10-20 Thread F. Xavier Ruiz
Dear All,

We have an immediate opening for a skilled post-doctoral researcher in the 
laboratory of Prof. Eddy Arnold at Rutgers University (NJ, USA). The aim of the 
project is to study the structure and function of human viral proteins, mainly 
polymerases from HIV-1, SARS-CoV-2 and other RNA viruses posing a pandemic 
threat, through X-ray crystallography and cryo-electron microscopy.

For more information about the position, please see the full advert: 
https://jobs.rutgers.edu/postings/145198 
Interested candidates should apply via the above link. For informal inquiries, 
please feel free to contact me directly.

Best wishes,

F. Xavier RUIZ
Assistant Research Professor
Arnold Laboratory Center for Advanced Biotechnology and Medicine Rutgers 
University
https://cabm.rutgers.edu/research/arnold-lab



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[ccp4bb] Postdoc position available

2021-08-05 Thread Tobias Beck
Dear all,

We have an opening for a Postdoc position in my group. The Beck group is
located at the University of Hamburg, with labs well-equipped for nano
chemistry and protein chemistry, and supported with computational
infrastructure for protein design. Moreover, state-of-the-art facilities
for structural characterizations such as PETRA III are close by.

The project will focus on machine learning approaches to guide the redesign
of protein containers. Towards this goal, previous knowledge on protein
assemblies and crystal structures will be be implemented. Identification of
suitable models will be carried out to connect the assemblies to surface
properties of proteins.

The position is available starting on October 1st 2021.

Full details of the post and the applications process are available here:
https://www.uni-hamburg.de/stellenangebote/ausschreibung.html?jobID=8d3f1e2aa16d641f16ae505621127752d3d7ee3e

Link to the group homepage:
https://www.chemie.uni-hamburg.de/institute/pc/arbeitsgruppen/beck.html

Deadline for applications is August 16 2021.

I'd appreciate it if you could pass this announcement on to potentially
interested candidates.
Please contact me for further information or informal inquiries: tobias.beck
@chemie.uni-hamburg.de

Best, Tobias.


Prof. Dr. Tobias Beck
University of Hamburg
Department of Chemistry
Institute of Physical Chemistry
Grindelallee 117
D-20146 Hamburg
Germany

phone:   +49 4042838 8210
fax:   +49 4042838 3462
web:   www.chemie.uni-hamburg.de/institute/pc/arbeitsgruppen/beck/




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[ccp4bb] postdoc position available in the lab of Prof. Eddy Arnold (Rutgers University, NJ, USA)

2021-01-21 Thread F. Xavier Ruiz
Dear All,

We have an immediate opening for a skilled post-doctoral researcher in the 
laboratory of Prof. Eddy Arnold at Rutgers University (NJ, USA). 
The aim of the project is to study the structure and function of human viral 
proteins and polyproteins, including from HIV-1 and SARS-CoV-2, through X-ray 
crystallography and cryo-electron microscopy. 
For more information about the position, please see the full advert: 
https://jobs.rutgers.edu/postings/124873 
Interested candidates should apply via the above link. For informal inquiries, 
please feel free to contact me directly.

Best wishes,

F. Xavier RUIZ

Assistant Research Professor
Arnold Laboratory
Center for Advanced Biotechnology and Medicine
Rutgers University
https://cabm.rutgers.edu/research/arnold-lab



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[ccp4bb] PostDoc position available immediately

2020-05-25 Thread Jesko Koehnke
Dear All,

my group is looking for a PostDoc for a collaborative project with
industry. The aim is the crystallisation and structure determination of
protein-natural product complexes. More details will be provided to
applicants selected for an interview. The position is available immediately
and will end 31.12.2021.

Best,

Jesko



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[ccp4bb] Postdoc position available in Single Particle CryoEM or Cryo-ET, Southern University of Science and Technology, China

2020-02-03 Thread Huawei Zhang
Dear colleagues,

We are looking for motivated postdoc researchers to work in the field of
osteoarthritis and exosome biogenesis using Single Particle CryoEM or
Cryo-ET in Dr. Daping Wang and Dr. Huawei ZHANG’s lab. By a combination of
structural biology, cell biology, biochemistry and biophysics, we aim to
understand the molecular mechanism of osteoarthritis pathogenesis and
exosome biogenesis, and pave the way for drug design (small molecules and
antibodies etc). For more details about our research field, pls see
http://www.szklte.com/?m=home&c=View&a=index&aid=73 or
https://www.sustech.edu.cn/en/zhanghuawei.html?lang=en

Our lab is affiliated to Southern University of Science and Technology
(SUSTech), Shenzhen, China. SUStech is a rapidly developing university and
has set up China’s largest CryoEM centre with 6 300Kv Titan krios electron
microscopes, together with 71 sets of related auxiliary instruments and
sample preparation facilities. Plenty of time slots  will be available for
internal users.

The candidate should already or will obtain PhD degree in related fields
including structural biology, biochemistry, biophysics or molecular biology
etc. He or she should have at least 1 publication to demonstrate the track
record. Experience in cryo-electron microscopy or sample preparation is a
plus.

Competitive salary will be provided together with fringe benefit, housing
allowance and yearly bonus.

The position will be open until filled. Interested applicants please send
your CV (including basic info, education info, techniques and working
experiences etc) and contacts of two referees to Dr. Huawei ZHANG at
zhw2...@gmail.com.

Thank you for your attention.



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[ccp4bb] Postdoc position available immediately

2019-11-18 Thread J Wu
A postdoctoral position is available immediately at Fox Chase Cancer Center 
(Philadelphia, PA) for a highly motivated individual in the field of structural 
biology or protein biochemistry. 

The main focus of the lab is to understand the biological controls of the 
signaling events involved in cell adhesion and migration. For this, we employ a 
combination of techniques including binding kinetics analysis, functional 
assays in mammalian cells, protein crystallography, electron microscopy, and 
genetic analysis. Our study will facilitate efforts to discover novel targets 
for therapeutic intervention of immune system disorders, tumor metastasis, and 
many other related diseases. More details can be found at 
https://www.foxchase.org/people/jinhua-wu.

The candidate is expected to have 3-5 years of experiences in  protein 
biochemistry, molecular biology, and X-ray crystallography. Prior experiences 
in mammalian cell culture, flow cytometry, and cancer biology, are desired but 
not required. Fox Chase Cancer Center is a long-standing NCI-designated 
Comprehensive Cancer Center with multidisciplinary research interests from 
basic biological sciences to drug development and clinical studies. The 
institute is located in a quiet, safe, friendly neighborhood at the outskirts 
of the city. It is one of the top-ranked work places for visiting scholars and 
postdoctoral researchers. We also offer an outstanding research environment and 
strong support for the career development for our scientists.

Please send a cover letter describing previous research experience and future 
plans, a current CV, and a list of three references to: Jinhua.wu(at)fccc.edu.



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[ccp4bb] Postdoc position available in Berkeley

2019-11-01 Thread Peter Zwart
Dear All,

We have a postdoc position available at LBNL to work on the development of 
computational approaches for twinned crystallographic data. This is an exciting 
opportunity to address a relatively common phenomenon in crystallographic data 
analysis for which there are currently limited twinning-aware approaches. The 
aim is to develop tools that impact substructure solution, molecular 
replacement, density modification and structure refinement.

Click the link below for more info or contact me directly for more information.

https://lbl.taleo.net/careersection/2/jobdetail.ftl?job=88480

Regards

Peter Zwart


-- 

P.H. Zwart
Staff Scientist
Molecular Biophysics and Integrated Bioimaging
Center for Advanced Mathematics for Energy Research Applications
Lawrence Berkeley National Laboratories
1 Cyclotron Road, Berkeley, CA-94703, USA
Cell: 510 289 9246
PHENIX:   http://www.phenix-online.org
CAMERA: http://camera.lbl.gov/
-


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[ccp4bb] Postdoc position available in an enzymology laboratory at Florida State University

2019-07-23 Thread Adarsh Kumar
Dear all

One postdoctoral position is available immediately in an enzymology laboratory 
to elucidate mechanisms of DNA/RNA synthesis, DNA lesion bypass, and base 
excision repair catalyzed by various human and viral DNA/RNA polymerases, and 
to mechanistically investigate gene editing enzymes including CRISPR/Cas9 and 
Cas13a. Background in structural biology (X-ray crystallography and/or CryoEM), 
biophysics, protein purification, and recombinant DNA techniques is preferred. 
Prior experience with DNA binding proteins would be an added advantage. An 
important criterion for selection will be the ability of the desired individual 
to pursue independent research in an active multi-disciplinary setting. 

Interested candidates should send a CV and a statement describing experience, 
goals, and reasons for the interest in this position, and arrange to have three 
letters of recommendation sent to: 
Dr. Zucai Suo
Eminent Professor and Dorian and John Blackmon Chair of Biomedical Science
Department of Biomedical Sciences
Florida State University - College of Medicine
Tallahassee, FL
Email: zucai@med.fsu.edu

Further information about the research projects in the Suo Lab can be obtained 
from https://med.fsu.edu/suolab/research
The list of publications can be found at https://med.fsu.edu/suolab/publications

Job Description:
Employer: Florida State University College of Medicine
Location: Tallahassee, Florida
Salary: NIH guidelines for post-doctoral salaries + benefits
Discipline: Life Sciences, Biochemistry, Biology, Biophysics, Structural 
Biology, and Biomedical Sciences
Position Type: Full Time
Organization Type: Academia
Job Type: Postdoc



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[ccp4bb] postdoc position available

2019-06-03 Thread Chang, Changsoo


Argonne National Laboratory seeks a postdoctoral researcher to join the 
Structural Biology Center (SBC) at the Advanced Photon Source (APS) to develop 
methods in crystallography and other techniques. Building on our expertise in 
high resolution de novo structure determination, serial crystallography and a 
long history of cutting edge experiments, we would like to bring the next 
generation of experiments to the SBC general user program. The postdoctoral 
fellow will develop hardware and software to analyze molecular changes of 
structures as diffraction data is collected and processed autonomously, will 
create the experimental scope, source samples, collect and analyze data.

The SBC is committed to research in these areas as the direction of the 
crystallography is being shifted and as APS will provide advanced capabilities 
after the major ongoing upgrade. Research in multimodal crystallography is 
growing and expected to continue to increase for years to come.


Please see link.

https://careers.peopleclick.com/careerscp/client_argonnelab/post_doc/gateway.do?functionName=viewFromLink&jobPostId=7771&localeCode=en-us


Changsoo Chang






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[ccp4bb] Postdoc position available in an enzymology laboratory at Florida State University

2019-05-29 Thread Adarsh Kumar
One postdoctoral position is available immediately in an enzymology laboratory 
to elucidate mechanisms of DNA/RNA synthesis, DNA lesion bypass, and base 
excision repair catalyzed by various human and viral DNA/RNA polymerases, and 
to mechanistically investigate gene editing enzymes including CRISPR/Cas9 and 
Cas13a. Background in structural biology (X-ray crystallography and/or CryoEM), 
biophysics, protein purification, and recombinant DNA techniques is preferred. 
Prior experience with DNA binding proteins would be an added advantage. An 
important criterion for selection will be the ability of the desired individual 
to pursue independent research in an active multi-disciplinary setting. 

Interested candidates should send a CV and a statement describing experience, 
goals, and reasons for the interest in this position, and arrange to have three 
letters of recommendation sent to: 
Dr. Zucai Suo
Eminent Professor and Dorian and John Blackmon Chair of Biomedical Science
Department of Biomedical Sciences
Florida State University - College of Medicine
Tallahassee, FL
Email: zucai@med.fsu.edu

Further information about the research projects in the Suo Lab can be obtained 
from https://med.fsu.edu/suolab/research
The list of publications can be found at https://med.fsu.edu/suolab/publications

Job Description:
Employer: Florida State University College of Medicine
Location: Tallahassee, Florida
Salary: NIH guidelines for post-doctoral salaries + benefits
Discipline: Life Sciences, Biochemistry, Biology, Biophysics, Structural 
Biology, and Biomedical Sciences
Position Type: Full Time
Organization Type: Academia
Job Type: Postdoc



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[ccp4bb] Postdoc Position Available at Fox Chase Cancer Center (Philadelphia)

2019-05-22 Thread J Wu
A postdoctoral position is available immediately at Fox Chase Cancer Center 
(Philadelphia, PA) for a highly motivated individual in structural biology and 
cell signaling.
 
The main focus of the lab is to understand the molecular basis for the cell 
signaling events that regulate cell motility. We collaborate with cancer 
biologists and clinicians at Fox Chase Cancer Center to investigate the 
pathological mechanisms of the signaling molecules in cancer development and 
metastasis. The lab is equipped with instruments to employ a combination of 
techniques including binding kinetics analysis, functional assays in mammalian 
cells, automated protein crystallography, and genetic analysis. Our study will 
contribute significantly to the understanding of the formation and regulation 
of cell migration and adhesion, and will facilitate efforts to discover novel 
targets for therapeutic intervention of tumor metastasis and other related 
diseases. More details can be found at 
https://www.foxchase.org/people/jinhua-wu.
 
The candidate should have strong experiences in at least one of the following 
research fields: protein biochemistry, cell biology, X-ray crystallography, and 
cancer biology. The candidate should receive a Ph.D. degree within three years. 
Fox Chase Cancer Center is a long-standing NCI-designated Comprehensive Cancer 
Center with multidisciplinary research interests from basic biological sciences 
to drug development and clinical studies. The institute is one of the 
top-ranked work places for postdoctoral researchers. It offers an outstanding 
research environment and strong support for postdoctoral career development, 
including subsidized housing and child care.
 
Please send a personal statement describing previous research experience and 
current interests, an updated CV, and a list of three references to: 
Jinhua.wu(at)fccc.edu.



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[ccp4bb] Postdoc position available in Indiana University School of Medicine

2018-10-29 Thread Takagi, Yuichiro
Dear Colleagues

We are looking for a highly motivated postdoctoral follow with a background in 
structural biology (X-ray crystallography, cryo-EM), to work on NIH-funded 
projects studying multi-protein complexes involved in eukaryotic transcription 
regulation. The information of this position is as follows:

Postdoctoral Fellow, Takagi Laboratory 
(https://medicine.iu.edu/research/faculty-labs/takagi/)
Department of Biochemistry and Molecular Biology
Indiana University School of Medicine

Who We Are:
My laboratory is interested in understanding the mechanisms of assembly, 
structure and function of large multi-protein complexes -“molecular machines” - 
involved in eukaryotic gene regulation, utilizing both cryo-EM and X-ray 
crystallography. We are particularly interested in the Mediator complex in both 
yeast and humans.

We believe that development and implementation of novel technologies is the key 
to unlocking the mysteries of how highly complex molecular machines (e.g. 
Mediator) function. Therefore, our overall research objective is two-fold: (i) 
development of novel technologies for studying multi-protein complexes, and 
(ii) application of these technologies to elucidate the structure and function 
of the Mediator complex.  In addition, we have developed a novel technology for 
producing pure preparations of difficult-to-express proteins and protein 
complexes, which has enabled several exciting ongoing projects with outstanding 
collaborators, including work on: plant RNA polymerases, DNA helicases, DNA 
repair complexes, RNA editing complex, and insulator complex.

 What We Offer:
1) State-of-the art protein and protein complex expression technologies (patent 
pending) enabling expression of difficult-to-express, problematic proteins and 
protein complexes

2) Accessibility to crystallization drop-setting robots, home X-ray sources, 
Synchrotron data collection at the Advanced Photon Source (APS) at Argonne 
National Laboratory (within a 3 hour drive from our lab), as well as 
electron-microscopy (EM) facility: Titan Krios, Talos Artica, and JOEL-FS3200

3) A one-on-one mentoring opportunity by which a postdoctoral fellow can learn 
the craft of designing research strategy, preparing compelling grant proposals, 
and paper-writing and presentation skills

4) The opportunity to work with multiple outstanding collaborators

Who Should Apply:
This position could be a great fit for you if:

- you have the expertise and experience in X-ray crystallography, and want to 
apply such skills toward structure determination of highly complex 
multi-protein complexes

- you are interested in learning and developing for the cutting-edge protein 
complex engineering and expression technologies

- you would like to extend your skill sets to cryo-EM

-you are self-confident and can communicate with the PI, other lab members, and 
collaborators with ease, and enjoy discussing research results and how to 
overcome technical challenges

- the specific research focus of our laboratory inspires you

- you love to gather information from the literatures  and helps generate 
creative ideas and technical solutions

- you relish working on technically challenging problems, which often require 
an extended persistent effort to crack


Job Description, Qualification, and Expectations:

Primary activities in this position include, but are not limited to:
- Expression and purification of the protein complexes for biochemical and 
structural studies
- Structure determination of the protein complexes by cryo-EM or/and X-ray 
crystallography
- Biochemical assays to characterize the recombinant protein complexes
- Providing intellectual contributions to the projects including writing 
manuscripts, fellowship application and helping PI for grant applications
- Ph.D. in structural biology (X-ray crystallography, cryo-EM) is strongly 
preferred 

If interested, please email a cover letter, CV, and two reference letters to 
ytak...@iu.edu 
Applications will be screened until a suitable candidate is found.  Indiana 
University is an equal opportunity/affirmative action employer.







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[ccp4bb] Postdoc position available at Florida State University

2018-09-24 Thread adarsh kumar
Dear all

One postdoctoral position is available immediately in an enzymology
laboratory to elucidate mechanisms of DNA/RNA synthesis, DNA lesion bypass,
and base excision repair catalyzed by various human and viral DNA/RNA
polymerases, and to mechanistically investigate gene editing enzymes
including CRISPR/Cas9 and Cas13a. Background in structural biology (X-ray
crystallography and/or CryoEM), biophysics, protein purification, and
recombinant DNA techniques is preferred. An important criterion for
selection will be the ability of the desired individual to pursue
independent research in an active multi-disciplinary setting. Interested
candidates should send a CV and a statement describing experience, goals,
and reasons for the interest in this position, and arrange to have three
letters of recommendation sent to: Dr. Zucai Suo, Eminent Professor and
Dorian and John Blackmon Chair of Biomedical Science, Department of
Biomedical Sciences, College of Medicine, Florida State University,
Tallahassee, FL. Dr. Suo can be contacted by email (zucai@med.fsu.edu).
Further information about the research projects in the Suo Lab can be
obtained from https://u.osu.edu/suolab/.

Employer: Florida State University College of Medicine
Location: Tallahassee, Florida
Salary: NIH guidelines for post-doctoral salaries + benefits
Discipline: Life Sciences, Biochemistry, Biology, Biophysics, Structural
Biology, and Biomedical Sciences
Position Type: Full Time
Organization Type: Academia
Job Type: Postdoc


*Regards*



*Adarsh Kumar, PhD*

*Suo Lab*

*Florida State University School of Medicine*


*Tallahassee, FL - 32304*



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[ccp4bb] Postdoc position available

2018-08-01 Thread Xiao Lei
*Postdoctoral Scholar Position on Investigating CRISPR Mechanism at
University of Southern California, Los Angeles, California, USA*



The Qin Laboratory in the Chemistry Department of the University of
Southern California invites applications for postdoctoral scholar positions
supported by funding from NIH and NSF. The work centers on investigating
mechanisms of target recognition by the programmable CRISPR nucleases that
are revolutionizing genome engineering. The projects use a combination of
biophysical techniques, including spin-labeling and EPR (a specialty of the
Qin lab, seehttp://pzqin.usc.edu/pzqhome/), fluorescence, and structural
characterization. Candidates with prior experience on protein expression,
mutagenesis, structural analyses (e.g., X-ray, NMR), and protein-nucleic
acid interaction are particularly welcome. Strong writing and communication
skills, as evidenced by first author publications, are highly desirable.



The appointment is available initially for three years contingent on
satisfactory research progress. Funding starts in Fall 2018, and salary
will commensurate with qualifications. To Apply, please email a cover
letter, CV and contact information for three references to Professor Peter
Qin, p...@usc.edu

*(PS.  Please do not reply to this email, I post this job for Dr. Peter
Qin, please directly contact with Dr. Peter Qin)*



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[ccp4bb] Postdoc Position available at Dr. Peter Qin lab at University of Southern California

2018-07-29 Thread Xiao Lei
*Postdoctoral Scholar Position on Investigating CRISPR Mechanism at
University of Southern California, Los Angeles, California, USA*



The Qin Laboratory in the Chemistry Department of the University of
Southern California invites applications for postdoctoral scholar positions
supported by funding from NIH and NSF. The work centers on investigating
mechanisms of target recognition by the programmable CRISPR nucleases that
are revolutionizing genome engineering. The projects use a combination of
biophysical techniques, including spin-labeling and EPR (a specialty of the
Qin lab, see http://pzqin.usc.edu/pzqhome/), fluorescence, and structural
characterization. Candidates with prior experience on protein expression,
mutagenesis, structural analyses (e.g., X-ray, NMR), and protein-nucleic
acid interaction are particularly welcome. Strong writing and communication
skills, as evidenced by first author publications, are highly desirable.



The appointment is available initially for three years contingent on
satisfactory research progress. Funding starts in Fall 2018, and salary
will commensurate with qualifications. To Apply, please email a cover
letter, CV and contact information for three references to Professor Peter
Qin, p...@usc.edu

*(PS.  Please do not reply to this email, I post this job for Dr. Peter
Qin, please directly contact with Dr. Peter Qin)*



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[ccp4bb] Postdoc Position available - Signalling and Structural Biology Lab, the Francis Crick Institute,

2018-05-18 Thread David Briggs
Dear all,


A four-year postdoc position is available in the Signalling and Structural 
Biology Laboratory at the Francis Crick Institute, London, UK, focusing on 
cryoEM / X-ray crystallography of Rho-dependent protein kinases assemblies.


Candidates with experience in biochemistry and/or structural biology are 
particularly encouraged to apply.


Closing date for applications is 30th May 2018.


Informal enquiries may be made to Prof Neil McDonald

(neil.mcdon...@crick.ac.uk).


Applications can be made through the Crick HR platform here: 
http://bit.ly/2rTlaoj


Kind regards,


Dave


--

Dr David C. Briggs

Senior Laboratory Research Scientist

Signalling and Structural Biology Lab

The Francis Crick Institute

London, UK

==

about.me/david_briggs

The Francis Crick Institute Limited is a registered charity in England and 
Wales no. 1140062 and a company registered in England and Wales no. 06885462, 
with its registered office at 1 Midland Road London NW1 1AT


[ccp4bb] Postdoc position available in structure-based antimicrobial drug development

2017-12-15 Thread Jon R Sayers
Job Reference Number: Job Title:
Contract Type: Working Pattern: Faculty:
Department:
Salary:
​ ​
£30,688 - £32,548 per annum​
Closing Date:
​ 15th Jan. 2018

​APPLY VIA Current vacancies link on https://www.sheffield.ac.uk/jobs
Search for job reference number
UOS017984
​ ​

Postdoctoral Research Associate in Structural Biology
​/Structure-based drug design​

We seek to appoint a Research Associate in Structural Biology to work on
the development of inhibitors of bacterial flap endonucleases (FEN) as
potential new antimicrobial drugs. This is a
​n university position for ​
16-month fixed-term funded by a research contract from an exciting new
University of Sheffield spin-out company founded to develop a new
generation of anti-bacterial agents capable of targeting antibiotic
resistant bacteria.
You will conduct world-class research to enable a structure-based drug
design approach to develop inhibitors of essential bacterial enzymes. Your
role will be to crystallize and determine the X-ray crystal structures of
FEN enzymes
​and to carry out structure-based drug screening/design
. You will work closely with a second Research Associate tasked with
protein manufacture, inhibitor characterization and development. We welcome
highly dedicated and enthusiastic candidates with the ability to develop
their scientific skills. You will possess or have submitted a PhD degree in
X-ray crystallography of protein molecules and have an interest
​and ideally experience​
in
​ in silico​
drug development. Success in this post may lead to an opportunity to
continue on the project subject to further funding being obtained.
FEN enzymes are involved in DNA replication and repair (see our recent
paper in Nature Structural and Molecular Biology on the mechanism). We are
using site-directed mutagenesis, crystallography and kinetic studies to
determine how these complicated enzymes function and you will apply this to
developing inhibitors in a structure-based approach. The groups are housed
within well-equipped laboratories with access to excellent core facilities
with state-of-the-art equipment for e.g. biological mass spectrometry,
Cryo-EM, X-ray crystallography, liquid handling robotics for high
throughput screening & crystallization, a range of microscopy facilities,
etc. You will join a multidisciplinary team made up of scientists from the
Sayers’ and Baker laboratories from the Department of Infection, Immunity
and Cardiovascular Disease, (IICD) and Department of Molecular Biology &
Biotechnology (MBB), respectively. This represents a collaboration between
two research institutes in Sheffield, namely, The Sheffield Institute for
Nucleic Acids (SInfoNiA) and The Flory Institute for Host-pathogen
Interactions.
You will hold a good honours degree in a relevant subject and a PhD in
macromolecular crystallography. This post is fixed term for 16 months, with
a start date of 1
​February
 2018 (or as soon as possible thereafter).
-- 
Professor Jon R Sayers, FRSB
Department of Infection, Immunity & Cardiovascular Disease
University of Sheffield Medical School
Beech Hill Rd
Sheffield
S10 2RX
United Kingdom

Tel: +44 (0)114 215 9552
Fax: +44 (0)114 271 1863
Email: j.r.say...@sheffield.ac.uk

http://www.sheffield.ac.uk/iicd/profiles/sayers


[ccp4bb] postdoc position available

2017-12-11 Thread Zheng, Hongjin
Dear Colleagues,

We are currently seeking a postdoctoral fellow in the laboratory of Dr. Hongjin 
Zheng at the University of Colorado, Anschutz Medical Campus, Denver, CO, USA. 
The successful candidate will join an energetic group investigating the 
structural and functional mechanisms of various disease-related membrane 
proteins and protein complexes, using primarily cryo-EM and X-ray 
crystallography. Our laboratory is well supported by the department and school 
of medicine, equipped with state-of-art cryo electron microscope with direct 
detector, in-home X-ray machine, NMR, and a great biophysics core.
The ideal candidate should hold a Ph.D. degree in the areas related to 
biological sciences, with experiences in molecular biology, protein 
biochemistry and structural biology. Interested applicants please send your CV 
to hongjin.zh...@ucdenver.edu.

Best,
Hongjin Zheng

-
Hongjin Zheng, Ph.D.
Assistant Professor
Biochemistry & Molecular Genetics
Anschutz Medical Campus
University of Colorado, Denver
12801 East 17th Ave
MS 8101, Rm L18-9111A
Aurora, CO 80045
Phone: 303-724-9374
Email: hongjin.zh...@ucdenver.edu



[ccp4bb] Postdoc Position Available in Structural and Functional Study of Macromolecular Complexes In Transcription And Repair at UCSD

2017-09-13 Thread Dong Wang
Please help to post following postdoc recruitment ad. Many thanks. 



A postdoc position, supported by NIH funding, is available in the lab of Dong 
Wang at University of California, San Diego. Our research focuses on the 
interplay between two fundamental processes: transcription and DNA repair. 
Current research projects focus on the X-ray and CryoEM structural elucidation 
and functional/biochemical study of macromolecular protein-nucleic acid 
complexes involved in transcription, chromatin remodeling, and DNA repair. 
Please visit http://pharmacy.ucsd.edu/labs/wang/publications/ 
  for details of our  recent 
research and publications.

We are looking for a highly motivated individual with experiences in 
biochemistry, and molecular biology, X-ray crystallography, or CryoEM. 
Candidates must have at least one original first author publication in the 
related field. We sincerely invite you join our small, but vibrant and highly 
productive team. Please send your CV, list of publications, and the names and 
Email addresses of 2-3 references to dongw...@ucsd.edu 
 before Oct 15, 2017.

 

---
best

Dong

Dong Wang
Associate Professor
University of California San Diego
Skaggs School of Pharmacy & Pharmaceutical Sciences
Department of Cellular and Molecular Medicine, School of Medicine
PSB 2266, MC 0625
9500 Gilman Drive,
La Jolla, CA 92093-0625
Phone: 858 822 5561
Email: dongw...@ucsd.edu




[ccp4bb] Postdoc position available - Imperial College London - Prof Dale Wigley

2017-05-04 Thread Wilkinson, Martin


——

Martin Wilkinson
mwilk...@ic.ac.uk

Imperial College
Lab 245
2nd Floor, SAF building
Imperial College Road
London
SW7 2AZ

——



HM2017001 Research Associate Advert QC SW - extended2.pdf
Description: HM2017001 Research Associate Advert QC SW - extended2.pdf


[ccp4bb] Postdoc position available at Emory University, Atlanta GA, USA

2016-12-21 Thread Conn, Graeme L
A postdoctoral position at Emory University is available immediately on an 
NIH-funded project investigating bacterial antibiotic-resistance ribosomal RNA 
methyltransferases. We use interdisciplinary approaches including structural 
biology, biochemistry, molecular biology and microbiology to address molecular 
mechanistic questions related to the activities of these antibiotic resistance 
determinants from both drug-producing and human pathogenic bacteria. The 
position is part of an on-going collaborative project between the groups of 
Drs. Graeme L. Conn and Christine M. Dunham, both located in the Department of 
Biochemistry, Emory University School of Medicine in Atlanta GA, USA. For more 
information on this project and recent publications please see:

http://www.biochem.emory.edu/conn

http://www.biochem.emory.edu/dunham

The Emory Department of Biochemistry has state-of-the-art shared facilities for 
crystallization and in-house X-ray data collection as well as providing regular 
synchrotron beamtime at the Advanced Photon Source (APS) through our membership 
of SER-CAT. Outstanding facilities for complementary biophysical approaches 
(e.g. HDX-MS, ITC, SPR, etc) are also available through the Emory integrated 
core facilities. Additionally, both labs have been at the forefront of 
developing the infrastructure for high-resolution single particle cryo-EM on 
the Emory campus (from 2017) which will be applicable to this project. We are 
also part of the Emory Antibiotic Resistance Center (ARC; see 
http://www.antibiotics.emory.edu/) which provides a diverse and intellectually 
stimulating environment for research and practice related to all aspects of 
bacterial antibiotic resistance.

Interested applicants should have a Ph.D. in biochemistry, molecular biology or 
structural biology, and, ideally, experience in X-ray crystallography and/ or 
high-resolution single particle cryo-EM. The ideal candidate will be highly 
motivated, possess excellent communication skills and the ability to work in a 
collaborative, team-oriented environment.

To apply, please e-mail a CV including a list of publications, a brief 
statement of experience and scientific interests, and contact information for 
three references to gc...@emory.edu.

_

Graeme L. Conn, Ph.D.
Department of Biochemistry
Emory University School of Medicine
1510 Clifton Road NE - Room 4135
Atlanta GA 30322 USA

E.mail gc...@emory.edu
Office (404) 727-5965
Lab (404) 712-0058
FAX (404) 727-2738
Lab Webpage
ORCiD
_







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[ccp4bb] Postdoc position available - PPI drug discovery

2015-03-19 Thread Beavil, Andrew

A 1-year crystallography postdoctoral position is available at King’s College 
London (Sutton, McDonnell & Beavil) to work on small-molecule inhibitors of a 
protein-protein interaction, as part of an ongoing collaboration with an 
industrial partner.

Please see: https://www.hirewire.co.uk/HE/1061247/MS_JobDetails.aspx?JobID=59133

Closing Date 24th March
Please contact brian.sut...@kcl.ac.uk if you 
have any informal enquiries.




--
-
Dr. Andrew J. Beavil,Phone: (+44) (0)20 78488064
Senior Lecturer in Molecular Biophysics  Fax  : (+44) (0)20 78486410



MRC & Asthma UK Centre in Allergic Mechanisms of Asthma
King's College London,
The Randall Division,
New Hunt's House, Email: 
andrew.bea...@kcl.ac.uk
Guy's Campus,
London Bridge,
London. SE1 1UL
-





[ccp4bb] Postdoc position available

2014-04-29 Thread Manfred S. Weiss



The Helmholtz Zentrum Berlin für Materialien und Energie, the 
Max-Delbrück-Center for Molecular Medicine Berlin, the Freie Universität 
Berlin, the Humboldt Universität zu Berlin and the Leibniz-Institute for 
Molecular Pharmacology jointly operate three experimental stations for 
bio-macromolecular crystallography within the Joint Berlin MX-Laboratory 
cooperation at BESSY II, one of the world's most modern synchrotron radiation 
sources for VUV and soft X-rays.

The Macromolecular Structure and Interaction Group of the Max-Delbrück-Center 
is seeking a

Post Doctoral Research Assistant

to conduct research on various structural biology / biochemistry projects of the 
MDC Macromolecular Structure and Interaction Group (headed by Prof. Dr. Udo 
Heinemann, 
https://www.mdc-berlin.de/1154162/de/research/research_teams/macromolecular_structure_and_interaction).
 According to research interests and qualifica­tions, the candidate may also 
participate in instrumental and/or computa­tion­al projects of the HZB-MX group. 
The successful candidate will also be involved in the operation of the BESSY II 
bio-macromolecular crystal­lo­graphy beamlines (headed by Dr. Uwe Müller & Dr. 
Manfred S. Weiss, http://www.helmholtz-berlin.de/bessy-mx) and will take part in 
graduate student education.

Initially, a two-year contract will be offered to the successful candidate with 
the possibility for an extension. The salary will be based on German federal 
TvÖD. The position is available immediately, and applications will be 
considered until the position is filled. The MDC is an equal-opportunity 
employer committed to excellence through diversity. Applications of women are 
explicitly encouraged.

Applicants should hold a Ph.D. in the biological, chemical or physical sciences 
and have a background in bio-macromolecular crystallography, biochemistry or 
computational sciences. The position also requires the documented ability to 
conduct independent research as well as excellent communication and 
interpersonal skills.

Please send applications (CV, list of publications, in one combined .pdf-file) 
in electronic form, with the Code MDC-MX-2014/1 to:
Dr. Uwe Müller (u...@helmholtz-berlin.de)


--
Dr. Manfred. S. Weiss
Helmholtz-Zentrum Berlin für Materialien und Energie
Macromolecular Crystallography (HZB-MX)
Albert-Einstein-Str. 15
D-12489 Berlin
GERMANY
Fon:   +49-30-806213149
Fax:   +49-30-806214975
Web:   http://www.helmholtz-berlin.de/bessy-mx
Email: mswe...@helmholtz-berlin.de




Helmholtz-Zentrum Berlin für Materialien und Energie GmbH

Mitglied der Hermann von Helmholtz-Gemeinschaft Deutscher Forschungszentren e.V.

Aufsichtsrat: Vorsitzender Prof. Dr. Dr. h.c. mult. Joachim Treusch, stv. 
Vorsitzende Dr. Beatrix Vierkorn-Rudolph
Geschäftsführung: Prof. Dr. Anke Rita Kaysser-Pyzalla, Thomas Frederking

Sitz Berlin, AG Charlottenburg, 89 HRB 5583

Postadresse:
Hahn-Meitner-Platz 1
D-14109 Berlin

http://www.helmholtz-berlin.de


[ccp4bb] Postdoc position available at the Clare Hall Laboratories, Cancer Research UK

2013-11-04 Thread Alessandro Costa

Dear all,

a postdoc position is available now at the Clare Hall laboratories, London 
Research Institute, Cancer Research UK.

Best
Alessandro



About the job

A postdoctoral position is available at the Clare Hall Laboratories, Cancer 
Research UK, in the research team of Dr. Alessandro Costa. The group combines 
biochemistry and three-dimensional cryo-electron microscopy to study the 
molecular mechanism of genome duplication in eukaryotic cells. The laboratory 
is fully equipped for molecular biology and protein work and houses cryo-grid 
preparation instruments, including a FEI Vitrobot Mark IV automated plunge 
freezer. In addition, the group enjoys access to state of the art core 
facilities at the London Research Institute, including cell services, protein 
purification, mass spectrometry, parallel computing and electron microscopy 
(housing two FEI Tecnai Spirit instruments). The cryo-EM work is performed 
locally on a JEM2100 electron microscope, while high-resolution data collection 
trips are periodically arranged to access the FEI Titan Krios at NeCEN, Leiden.



About you

We are looking for a highly motivated individual with a passion for mechanistic 
enzymology. Candidates should hold a PhD in structural biology, biochemistry or 
related fields. A strong background in protein biochemistry / in vitro 
reconstitution of multi-protein complexes will be a plus. Alternatively, a 
focused expertise in cryo-electron microscopy will be considered an advantage.


The LRI will transfer to the Francis Crick Institute in 2015.

Please, follow this link if you wish to apply:

https://cancer-research-uk-jobs.tal.net/vx/lang-en-GB/mobile-0/appcentre-2/brand-2/user-72/xf-b7e041672dfe/candidate/so/pm/1/pl/6/opp/273-Postdoctoral-Researcher/en-GB



Alessandro Costa, PhD
London Research Institute
Clare Hall Laboratories
Cancer Research UK
South Mimms
Herts EN6 3LD, UK

Tel (within UK): 01707 625740
Tel (international): +44 1707 625740

E-mail: alessandro.co...@cancer.org.uk
http://www.london-research-institute.org.uk/research/alessandro-costa

NOTICE AND DISCLAIMER
This e-mail (including any attachments) is intended for the above-named 
person(s). If you are not the intended recipient, notify the sender 
immediately, delete this email from your system and do not disclose or use for 
any purpose. 

We may monitor all incoming and outgoing emails in line with current 
legislation. We have taken steps to ensure that this email and attachments are 
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Cancer Research UK
Registered charity in England and Wales (1089464), Scotland (SC041666) and the 
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A company limited by guarantee.  Registered company in England and Wales 
(4325234) and the Isle of Man (5713F).
Registered Office Address: Angel Building, 407 St John Street, London EC1V 4AD.

[ccp4bb] Postdoc Position Available

2013-08-10 Thread cmqian
Postdoctoral fellow, structural biology in DNA Damage Response, the University 
of Hong Kong, Hong Kong

We currently have the opportunity to recruit a highly-motivated postdoctoral 
fellow to work on molecular mechanisms of intra-S-phase checkpoint activation 
in response to DNA damage. The candidate should have a strong background in 
macromolecular crystallography or protein NMR. A highly competitive salary 
commensurate with qualifications and experience will be offered. Annual leave 
and medical benefits will also be available. 

Interested candidates should email their CV, a summary of research 
experience/accomplishments, and arrange for 3 letters of reference to be sent 
directly to Dr. Chengmin Qian (cmq...@hku.hk).


[ccp4bb] Postdoc position available at UT Southwestern Medical Center at Dallas

2013-07-12 Thread Hong Zhang
We are looking for one or two highly motivated and multi-talented postdoctoral 
researcher(s) to join a collaborative project studying the structure and 
mechanism of circadian clocks (See Huang et al. 
  2012 Science). The 
overall goal of the project is to understand how various multi-domain clock 
proteins interact with each other; and how these interactions modulate the 
clock-mediated transcription activation. Person(s) working on this project will 
have a unique opportunity to gain some unusual insights into the molecular 
clockworks governing our sleep-wake cycles.

 

Candidates should have a Ph.D. degree in a relevant field and must be 
proficient in molecular cloning, protein expression, purification, 
crystallization, and X-ray crystal structure determination. Additional 
experiences in eukaryotic protein expression systems, cell culture, various 
biochemical and biophysical techniques to study protein-protein interactions 
are also highly desirable. 

 

To apply, please email CV and contact info of two or more referees to 
zh...@chop.swmed.edu.

 

 

All the Best,

 

Hong Zhang, Ph.D.

Associate Professor

Department of Biophysics and Department of Biochemistry

UT Southwestern Medical Center at Dallas

4323 Harry Hines Blvd.

Dallas, Texas 75390-8816

Phone: 214-645-6372

Fax:   214-645-5948

http://profiles.utsouthwestern.edu/profile/23445/hong-zhang.html

 

 



[ccp4bb] postdoc position available in antibiotics uptake, Newcastle University (UK)

2013-03-18 Thread Bert Van-Den-Berg
An immediate position is available for up to 5 years for an enthusiastic and 
highly motivated postdoctoral Research Associate in the area of Outer Membrane 
Uptake of Antibiotics. You will participate in a European consortium 
("TRANSLOCATION") consisting of academic labs, small biotech firms and big 
pharma. The overall goal of the consortium is to understand antibiotics 
translocation across the outer membrane of pathogenic Gram-negative bacteria, 
as part of the Innovative Medicines Initiative (IMI) project “New Drugs for Bad 
Bugs”. The project at Newcastle University (UK) focuses on determining crystal 
structures of outer membrane channels with and without bound antibiotics, and 
on determining the specificity of antibiotics uptake by developing and 
performing in vivo and in vitro transport assays. Relevant experience in these 
techniques is expected from the applicant. The successful candidate will have a 
PhD or previous post-doctoral experience in X-ray crystallography and 
biochemistry or biophysics and should have published at least one first author 
paper in a leading journal.
Further information regarding this post can be obtained by contacting Prof Bert 
van den Berg (bert.van-den-b...@ncl.ac.uk). 



[ccp4bb] Postdoc position available at the University of Oregon

2012-03-13 Thread Brad Nolen
The Nolen lab in the Institute of Molecular Biology at the University of Oregon 
is seeking a highly motivated postdoctoral researcher to join our lab full time 
on a flexible start date. Our interest is in understanding the molecular basis 
for the regulation of the cytoskeleton. We are currently focusing on proteins 
that control the assembly and disassembly of actin filaments. Using a 
combination of x-ray crystallography, biochemistry, biophysics, cell biology, 
and single molecule fluorescence microscopy we seek to understand the 
structure-function relationships of these proteins and how their molecular 
mechanisms relate to their cellular activities.
 
For full position information and application procedure, please see:  
http://hr.uoregon.edu/jobs (see posting # 12090).  Candidates who promote and 
enhance diversity are strongly desired. 
 
The University of Oregon is an Equal Opportunity/Affirmative Action Institution 
committed to cultural diversity and compliance with the Americans with 
Disabilities Act.


[ccp4bb] Postdoc position available at Imperial College

2011-10-21 Thread Brick, Peter
Dear all,

A postdoc position is available in Stephen Curry's lab at Imperial College 
London.
See: http://www.jobs.ac.uk/job/ADK187/research-associate/
Peter

Research Associate
Imperial College London - Division of Cell & Molecular Biology, Faculty of 
Natural Sciences

Salary: £31,300 - £39,920 per annum

A Research Associate post is available to join Prof Stephen Curry's research 
group on the structural biology of enzymes from RNA viruses, within the 
Division of Cell & Molecular Biology. The position is based at the South 
Kensington Campus of Imperial College London.

Our recent work has established new breakthroughs in the structural and 
functional analyses of proteases, polymerases and helicases from picornaviruses 
and caliciviruses (see http://www.bio.ph.ic.ac.uk/~scurry/ for publications. We 
are now looking to take this work forward in exciting new directions.

The post will involve taking on the role of lead researcher on a project to 
investigate structural and functional aspects of enzymes from RNA viruses. The 
project is of a highly multi-disciplinary nature and will likely involve 
protein structure determination by protein crystallography and NMR (the latter 
in collaboration with Prof Matthews' group).

The successful candidate should have or be about to receive a PhD degree in a 
relevant subject, preferably structure determination by protein 
crystallography, or have equivalent level of professional qualifications and 
experience. Previous experience of working in a structural biology research 
environment and knowledge and experience of X-ray data collection at 
synchrotron sources, structure determination of macromolecules by X-ray 
crystallography, cloning, over-expression and purification of proteins and 
preparation and handling of recombinant proteins are essential.

A good understanding of protein over-expression in E. coli (with and without 
minimal media), and requirements of sample preparation for NMR methods are 
desirable. Use of the Linux operating system, and data processing with the CCP4 
package, CNS or Phenix refinement and model building in O/coot would be also an 
advantage.

You must have demonstrable ability to learn new techniques, to work 
independently and with imagination.

This is a fixed term position available immediately for up to 3 years.

Our preferred method of application is online via our website 
http://www3.imperial.ac.uk/employment (please select "Job Search" then enter 
the job title or vacancy reference number including spaces NS 2011 200 DPN into 
"Keywords"). Please complete and upload an application form as directed, 
attaching a curriculum vitae, a cover letter and the name and contact details 
of two referees.  For informal enquiries please contact Dr Stephen Curry via 
email s.cu...@imperial.ac.uk.

Alternatively, if you are unable to apply online, please contact Hafiza Bibi by 
email h.b...@imperial.ac.uk to request an application form.

Closing date: 2 November 2011

Committed to equality and valuing diversity. We are also an Athena Bronze SWAN 
Award winner, a Stonewall Diversity Champion and a Stonewall Top 100



[ccp4bb] Postdoc position available

2011-07-28 Thread Marc Kvansakul
SUMMARY DESCRIPTION: Structural biology of virus-host interactions
 

The Kvansakul Laboratory is seeking a postdoctoral fellow to investigate
the structural basis of inhibition of programmed cell death during viral
infection (e.g. Kvansakul et al 2007 Mol. Cell 25: 933 ­ 942, Kvansakul et
al Cell Death Differ 2008 15: 1564 ­ 1571, Kvansakul et al 2010 PLoS
Pathogens Dec 23;6(12):e1001236). This position offers the opportunity to
work in a highly collaborative and stimulating environment. The Kvansakul
Lab is part of the recently established La Trobe Institute for Molecular
Sciences (LIMS) at La Trobe University, Melbourne, Australia. LIMS is a
multidisciplinary institute that brings together the Departments of
Biochemistry, Chemistry, Genetics and Pharmacy.


 
The successful candidate will have the opportunity to:

 
1.Express and purify viral and host proteins and their complexes
2.Investigate different host binding partners for viral effector
proteins and their affinities
3. Crystallize and determine the macromolecular structure of these
proteins and their complexes with ligands
 

START DATE: The position is available immediately for 2 years in the first
instance.
 

REQUIREMENTS:
Ph.D. in biochemistry, biophysics or structural biology. Experience with
expression of recombinant proteins in a variety of hosts (bacteria, yeast,
insects) and purification of proteins to a high degree of homogeneity are
required. Prior experience with protein crystallization and structure
determination is strongly desirable. Experience with biochemical assays
and analyzing protein-protein interactions is also highly desirable. For
more details see 
http://jobs.latrobe.edu.au/jobDetails.asp?sJobIDs=545338&lWorkTypeID=&lLoca
tionID=&lCategoryID=&stp=AW&sLanguage=en
 

For informal enquiries please email m.kvansa...@latrobe.edu.au or come to
the IUCr 2011 in Madrid.
 

APPLICATION:
Closing date is September 11th. Please apply online at
http://jobs.latrobe.edu.au/jobDetails.asp?sJobIDs=545338&lWorkTypeID=&lLoca
tionID=&lCategoryID=&stp=AW&sLanguage=en
 


[ccp4bb] postdoc position available

2011-04-18 Thread Qun Wan
*A post-doctoral opening in protein crystallography* in the laboratory of
Chris Dealwis at the Cleveland Center for Membrane and Structural biology.
The project involves structure determination of protein-protein complexes
and membrane proteins. We are seeking for an individual that has a Ph.D in
protein crystallography. Some basic biochemistry skills involving protein
expression and purification will be extremely valuable. Candidates should
send their CV to Chris Dealwis (cxd...@case.edu) in the Department of
Pharmacology, Case Western Reserve University, Cleveland, OH, USA.


[ccp4bb] Postdoc position available, University of Bristol, UK

2011-02-28 Thread Paul Race
Dear all,

I have a 3 yr postdoc position available in my lab (Biochemistry, 
Bristol), starting early/mid April. Please see below for further particulars. 
Informal enquires welcome, though full applications MUST be made via the 
University of Bristol website 
(http://www.bris.ac.uk/boris/jobs/feeds/ads?ID=93852).

   Cheers,
 Paul


Research Assistant (ref. 16077)
School of Biochemistry
Contract: Fixed Term Contract (36 months)

Salary:£29,972 - £33,734

Grade:Level a in Pathway 2

Closing date for applications:9:00am 22 Mar 2011

Anticipated interview date:01 Apr 2011

Description
Working in the group of Dr Paul Race, you will undertake a BBSRC funded 
research project investigating the structural basis of natural product 
biosynthesis in terrestrial bacteria. You will have (or shortly have) a PhD in 
chemistry, biochemistry or a related discipline, and a proven track record in 
recombinant protein expression, purification and crystallisation, allied to 
significant experience in the determination of protein structures using 
macromolecular X-ray crystallography. Previous experience in electron and/or 
cryo-electron microscopy and a background in structural enzymology would be 
considered advantageous. 

You should be an enthusiastic and innovative scientist, a good team worker and 
an excellent communicator. The position is full-time and funding is available 
for three years currently.

If successful, you may be appointed either on a fixed term or a permanent 
contract depending on the extent of your previous relevant research experience. 
Further information can be found at www.bristol.ac.uk/personnel/ftc/


Dr Paul Race
Royal Society URF
School of Biochemistry
University of Bristol
BS8 1TD

paul.r...@bristol.ac.uk
Tel. +44 (0)117 331 2150
Fax. +44 (0)117 331 2168

http://www.bris.ac.uk/biochemistry/research/pr.html



[ccp4bb] Postdoc position available at University of Washington Seattle

2010-07-16 Thread Peter Hsu
The Varani group at the University of Washington is looking for a postdoc to 
work in the area of RNA structural biology, primarily on RNA:protein and 
protein:protein complexes involved in RNA processing.

Candidate must have a PhD in biochemistry or related fields, and a background 
in crystallography. If interested, please send CV and references to 
var...@chem.washington.edu


[ccp4bb] postdoc position available immediately at Oklahoma State University

2010-02-26 Thread Junpeng Deng
A postdoctoral fellow position is available immediately in the 
Department of Biochemistry and Molecular Biology, Oklahoma State University to 
study structure and function of protein complexes.
Interested research areas include cytokine signaling and insect innate immune 
system.

Applicants should have a recent PhD in structural biology, biochemistry, 
molecular biology, cell biology or a related area. Good experiences in protein 
crystallography, protein expression and purification by using both
E.coli and insect cell systems are expected. Selected recent publications:

1)Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20711-5.
2)Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1499-504. 
3)Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17002-6

Interested and motivated individuals  should place inquiry directly to: 
junpeng.d...@okstate.edu. Please have three references sent directly to this 
email address as well.
thanks.

Junpeng Deng, Ph.D
Assistant Professor
248A Noble Research Center
Dept. of Biochemistry and Molecular Biology
Oklahoma State University
Stillwater, OK 74078
405-744-6192 (O) 405-744-7799 (fax)
http://biochemistry.okstate.edu





[ccp4bb] Postdoc position available @Rossmann lab, Purdue University

2009-09-30 Thread Long Li
A post-doctoral position is available in a virus structure laboratory. 
Experience in macromolecular crystallography, electron microscopy, 
molecular biology and protein chemistry is desirable. Please e-mail 
applications to Michael Rossmann, _...@purdue.edu _ 
(dept of Biological Sciences, Purdue University, West Lafayette, IN 
47907, USA).


[ccp4bb] postdoc position available

2009-07-07 Thread Wei Zhang
A post-doctoral associate position is available in the Institute of 
Molecular Virology, University of Minnesota to study the cell entry 
mechanism of small envelope viruses (Zhang, W., et al 2002. J. Virol. 
76:11645-11658; Kielian, M., and F.A. Rey. 2006, Nature Rev. Microbiol. 
4:67-76.) using cryo-electron microscopy (cryo-EM) (Baker, T. S., et al. 
Microbiol. Molec. Biol. Reviews 63:862-922) and other biochemical and 
biophysical methods. Specifically, identifying the steps and determination 
of the type-II viral fusion protein oligomerization, re-organization during 
low-pH triggered membrane fusion. Candidates should have a PhD and training 
in virology, structural biology, biophysics or related fields. Please send 
cv, research experience and three references to Dr. Wei Zhang 
(zhang...@umn.edu)


[ccp4bb] postdoc position available

2009-06-02 Thread Peijun Zhang
POSTDOCTORAL FELLOW POSITION, UNIV. OF PITTSBURGH School of Medicine

A postdoctoral fellow position is available immediately in the Zhang
laboratory at the University of Pittsburgh to study HIV capsid protein and
host cell partner interactions using cryoEM methods. We are one of the three
NIH funded centers for structural determination of HIV/Host complexes
(http://www2.structbio.pitt.edu/hivppi/site/), and this position is
supported by the center grant.  

Motivated candidate with strong interest in cryo-electron microscopy of
complex molecular assemblies and solid background in structural biology,
biophysics, biochemistry or a related field are all encouraged to apply.
Research experience in the following area(s) is plus: 1) HREM or cryo-EM, 2)
image processing and/or 3) protein biochemistry/biophysics.

Interested candidates should send an application, including a CV, areas of
expertise and interests, publications list, and names and contact
information for 3 references to

Dr. Peijun Zhang
2050 BST3
Dept. of Structural Biology
Univ. of Pittsburgh School of Medicine
3501 5th Ave, Pittsburgh, PA 15260
p...@pitt.edu 

Our laboratory is within the newly established Dept. of Structural Biology,
fully equipped for all aspects of molecular biology and protein biochemistry
and has direct access to FEI Polara 300kv with helium stage, TF20 FEG, both
with high-resolution 4kx4k CCD cameras, T12spirit with 2kx2k camera, and FEI
vitrobot.  The laboratory also has access to the protein expression and
purification facilities, state-of-the-art NMR spectrometers and X-ray
crystallography instrumentation, as well as the many biophysical, imaging
and computing resources within the department.  Description of lab research
can be found at:
http://www.structbio.pitt.edu/drupal-5/?q=peijun-zhang

Applications will be reviewed as they are received and until the position is
filled.  
 


[ccp4bb] postdoc position available

2009-05-22 Thread Wen Jiang
A postdoc position is immediately available in the Jiang laboratory
(http://jiang.bio.purdue.edu) at the Markey Center of Structural
Biology and Department of Biological Sciences, Purdue University, West
Lafayette, Indiana, USA. Our research focuses on structural studies of
large macromolecular complexes and viruses using single particle
cryo-electron microscopy and 3-D reconstruction. Purdue is currently
equipped with two FEI FEG cryo-microscopes (200kV and 300kV) and will
install a FEI Titan Krios 300kV microscope later this year in our new
structural biology building. We are seeking a highly motivated
individual with extensive experience in structural biology and protein
biochemistry. The applicant should be a team player that enjoys
working in a collaborative environment. Please send cover letter, CV,
statement of research accomplishments and interests, and three
references to Dr. Wen Jiang (jian...@purdue.edu). Applications will be
reviewed until the position is filled.


[ccp4bb] Postdoc position available at UT Southwestern Medical Center

2009-05-13 Thread Xuelian Sue Luo
A postdoctoral position is available at the Department of Pharmacology, UT 
Southwestern 
Medical Center at Dallas, TX.  Our lab uses both NMR and X-ray crystallography 
to 
characterize the atomic structures of macromolecules involved in cancer-related 
signaling 
pathways.  We are also interested in validation of structure-based functional 
hypotheses 
using biochemical and cell biological approaches.  Applicants should be highly 
motivated 
individuals and must have a recent PhD degree in biochemistry, biophysics or 
other related 
field.  Experience in molecular biology, large-scale protein expression and 
purification, and 
X-ray crystallography is strongly preferred.  Interested applicants should send 
his/her CV 
with names of three referees to:

Xuelian Sue Luo, Ph.D.
Assistant Professor
Department of Pharmacology
UT Southwestern Medical Center
6001 Forest Park Road, ND6.136CC
Dallas, TX 75390-9041
Email: xuelian@utsouthwestern.edu


[ccp4bb] Postdoc position available in Uppsala, Sweden

2009-03-13 Thread Yafei Huang
Structural and functional studies of a proton pump and membrane transporters

A post-doc position is available in the membrane protein structural biology 
group at the 
Department of Molecular Biology/Swedish University of Agricultural Sciences 
(SLU). The 
aim of the research is to understand the structure and functions of integral 
membrane 
proteins. 

The successful candidate will be involved in both crystallographic and 
biochemical studies 
of the target proteins. Frequent short trips to Grenoble, France for data 
collection would 
be necessary. The lab is situated at the Biomedical Center (BMC) in Uppsala, 
Sweden. 

The applicant should hold a PhD and have a strong background in protein 
chemistry, 
preferably x-ray crystallography. Experience with membrane proteins is a great 
advantage. You must be able to work independently but also interact/collaborate 
with 
group members and collaborators. Strong written and oral English communication 
skills 
are required. The projects involve national and international collaborations.

The application must include your CV, list of publications, previous research 
accomplishments (one page) and names and contact information of at least two 
academic 
references. The position is for up to three years. Further inquires and 
applications should 
be sent to:

Yafei Huang
Department of Molecular biology
Swedish University of Agricultural Sciences (SLU)
Uppsala Biomedical Center (BMC)
Box 590
S-751 24 Uppsala
Sweden
Phone: +46 (0)18 4714523
Fax: +46 (0)18 536971
e-mail:ya...@xray.bmc.uu.se