Nonparametric multiple comparison

2002-03-02 Thread Alfred Barron

Hi All,

How reliable is Dunnett's comparison (w/control) when
applied to ranked data ? This appears to be an ad hoc
nonparametric multiple comparison with a test
statistic based on group rank sums in place of group
means and a standard error of sqrt[n(np)(np+1))/6] 
My guess is that it's unstable for small samples

I found reference to it in Zar, Biostatistical
Analysis (1974) (only edition in our library)  
The standard error is cited to Wilcoxon and Wilcox
(1964)(rare ?) Why 6 instead of 12 ? 

thanks,
Al Barron
Metuchen, NJ


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NJ Stat Conference: Deming Applied Statistics, Dec 10-13

2001-11-17 Thread Alfred Barron

  ANNOUNCING...

  The 57th Annual Deming Conference 
 on Applied Statistics
   Atlantic City, New Jersey
  December 10-13, 2001
  
 For details, registration costs, etc. see

  http://nimbus.ocis.temple.edu/~kghosh/deming01/

 The Program will include:
==
   Regression Modeling Strategies
   Professor Frank E. Harrell Jr. 
   University of Virginia
 
 • Modeling Variance and Covariance Structure 
   in Mixed Linear Models 
   Professor Ramon C. Littell 
   University of Florida 
 
1:00-4:00 
 • Bayesian Computation and its Application  
   to Non-linear Classification and Regression 
   Professor Bani K. Mallick
   Texas AM University

 • Analysis of Covariance: Repeated Measures 
   and Some Other Interesting Applications 
   Professor George A. Milliken 

   Statistical Methods for Clinical Trials
   Mark X. Norleans, M.D., Ph.D. 
   The National Cancer Institute
 
 • Experiments: Planning, Analysis and Parameter   
   Design Optimization 
   Professor Jeff Wu 
   University of Michigan 
 
1:00-4:00 
 • Sequential Clinical Trials: Design,
   Monitoring  Analysis 
   Vlad Dragalin, PhD 
   GlaxoSmithKline

 • Multiple Comparisons for Making Decisions 
   Professor Jason C. Hsu 
   Ohio State University  
 
   Simultaneous Monitoring and Adjustment 
   Professor J. Stuart Hunter 
   Princeton University 
 
 • Applied Logistic Regression 
   Professor Stanley A. Lemeshow 
   Ohio State University 
 
1:00-4:00 
 • Permutation Methods: A Distance 
   Function Approach 
   Professor Paul W. Mielke, Jr. 
   Colorado State University 

 • Approaches to the Analysis of Microarray Data 
   and Related Issues 
   Profs Elisabetta Manduchi and Warren Ewens 
   University of Pennsylvania  
 
 • Experimental Design and the Statistical Analysis 
   of Spotted Microarrays 
   Professor Kathleen Kerr 
   University of Washington 

 • Challenges Posed by the Human Genome Project 
   Professor Warren Gish 
   Washington University in St. Louis
 
   Measurement Error in Nonlinear Models 
   Professor David Ruppert 
   Cornell University 
 
 




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Conference: Deming Applied Statistics, NJ, Dec 10-13

2001-11-02 Thread Alfred Barron

  ANNOUNCING...

  The 57th Annual Deming Conference 
 on Applied Statistics
   Atlantic City, New Jersey
  December 10-13, 2001
  
 For details, registration costs, etc. see

  http://nimbus.ocis.temple.edu/~kghosh/deming01/

 The Program will include:
==
   Regression Modeling Strategies
   Professor Frank E. Harrell Jr. 
   University of Virginia
 
 • Modeling Variance and Covariance Structure 
   in Mixed Linear Models 
   Professor Ramon C. Littell 
   University of Florida 
 
1:00-4:00 
 • Bayesian Computation and its Application  
   to Non-linear Classification and Regression 
   Professor Bani K. Mallick
   Texas AM University

 • Analysis of Covariance: Repeated Measures 
   and Some Other Interesting Applications 
   Professor George A. Milliken 

   Statistical Methods for Clinical Trials
   Mark X. Norleans, M.D., Ph.D. 
   The National Cancer Institute
 
 • Experiments: Planning, Analysis and Parameter   
   Design Optimization 
   Professor Jeff Wu 
   University of Michigan 
 
1:00-4:00 
 • Sequential Clinical Trials: Design,
   Monitoring  Analysis 
   Vlad Dragalin, PhD 
   GlaxoSmithKline

 • Multiple Comparisons for Making Decisions 
   Professor Jason C. Hsu 
   Ohio State University  
 
   Simultaneous Monitoring and Adjustment 
   Professor J. Stuart Hunter 
   Princeton University 
 
 • Applied Logistic Regression 
   Professor Stanley A. Lemeshow 
   Ohio State University 
 
1:00-4:00 
 • Permutation Methods: A Distance 
   Function Approach 
   Professor Paul W. Mielke, Jr. 
   Colorado State University 

 • Approaches to the Analysis of Microarray Data 
   and Related Issues 
   Profs Elisabetta Manduchi and Warren Ewens 
   University of Pennsylvania  
 
 • Experimental Design and the Statistical Analysis 
   of Spotted Microarrays 
   Professor Kathleen Kerr 
   University of Washington 

 • Challenges Posed by the Human Genome Project 
   Professor Warren Gish 
   Washington University in St. Louis
 
   Measurement Error in Nonlinear Models 
   Professor David Ruppert 
   Cornell University 
 
 




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Education is a national security issue

2001-10-11 Thread Alfred Barron

I'd like to share the following article in honor
of those who perished a month ago in the Sept. 11
terrorist attacks.

Knowing that there are positive and constructive
options to follow is reassuring that there is hope 
for our children.

Al

=
Thursday, October 11, 2001  

U.S. education secretary calls for high science and
math goals. Rod Paige spoke during a conference at
Penn. Education is a national security issue, he
said. 

By Connie Langland 
INQUIRER STAFF WRITER
 
U.S. Secretary of Education Rod Paige said yesterday
that creating a national education system that sets
high standards in math, science and other basic skills
is an essential part of building a strong nation. 
Education is a national security issue, Paige told
education researchers from six nations who are meeting
in Philadelphia. 

Paige credited former Gov. Tom Ridge for emphasizing
education. Ridge left the office for the cabinet-level
post of director for homeland security. 

The events of Sept. 11 have had a great effect on all
of us, but it has not deterred us from our goal to
create an education system that will leave no child
behind, Paige said. 

We will not be content with educating just some
children, he said. Every child must learn and do
well. 

The education secretary - former superintendent of the
Houston system - endorsed the efforts of the
researchers gathered at the Six Nation Education
Research Project Conference, which is being held by
the University of Pennsylvania's Graduate School of
Education. 

He lauded their efforts to identify the resources and
research that create teaching methods that work - and
don't work. He said those studies would benefit
educational efforts here and throughout the world. 
For seven years, researchers from China, Germany,
Japan, Singapore, Switzerland and the United States
have studied how nations perform in such areas as math
and science education, vocational education and higher
education, and what variables contribute to strong or
poor performances. 

In mathematics, setting high standards is key, said
Erling Boe, professor of education in the Graduate
School of Education at Penn, who, with colleagues at
Penn and Pennsylvania State University, studied how
countries teach math and science. 

Students do better in math in countries that are
tough on math students, said Boe, noting that when
asked whether they do well in math, students in those
countries tend to disagree. 

In countries with lax academic standards in math and
science, he said, students often have the opinion that
they are good in those subjects. 

Of about 40 countries, the United States ranks in the
middle in math and science achievement, according to
international studies. 

Yesterday afternoon, Paige visited Conestoga High
School in Berwyn, Chester County, to observe the
start-up of an Internet-based education portal that
will link teachers, parents and students in four
states - Pennsylvania, New Jersey, Delaware and
Maryland.



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saddlepoint

2001-10-08 Thread Alfred Barron

I've begun looking at saddlepoint approximation,
in particular, for the distribution tail. I've 
also taken a peak at Laplace approximations. This
stuff appears to be rather analytical. Does anyone
have any examples, maybe some with SAS or S code?

thanks,
Al Barron
Metuchen, NJ

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Deming Applied Stat Conf.,NJ, Dec 10-13

2001-10-08 Thread Alfred Barron


  ANNOUNCING...

  The 57th Annual Deming Comnference 
 on Applied Statistics
   Atlantic City, New Jersey
  December 10-13, 2001
  
 For details, registration costs, etc. see

  http://nimbus.ocis.temple.edu/~kghosh/deming01/

 The Program will include:
==
   Regression Modeling Strategies
   Professor Frank E. Harrell Jr. 
   University of Virginia
 
 • Modeling Variance and Covariance Structure 
   in Mixed Linear Models 
   Professor Ramon C. Littell 
   University of Florida 
 
1:00-4:00 
 • Bayesian Computation and its Application  
   to Non-linear Classification and Regression 
   Professor Bani K. Mallick
   Texas AM University

 • Analysis of Covariance: Repeated Measures 
   and Some Other Interesting Applications 
   Professor George A. Milliken 

   Statistical Methods for Clinical Trials
   Mark X. Norleans, M.D., Ph.D. 
   The National Cancer Institute
 
 • Experiments: Planning, Analysis and Parameter   
   Design Optimization 
   Professor Jeff Wu 
   University of Michigan 
 
1:00-4:00 
 • Sequential Clinical Trials: Design,
   Monitoring  Analysis 
   Vlad Dragalin, PhD 
   GlaxoSmithKline

 • Multiple Comparisons for Making Decisions 
   Professor Jason C. Hsu 
   Ohio State University  
 
   Simultaneous Monitoring and Adjustment 
   Professor J. Stuart Hunter 
   Princeton University 
 
 • Applied Logistic Regression 
   Professor Stanley A. Lemeshow 
   Ohio State University 
 
1:00-4:00 
 • Permutation Methods: A Distance 
   Function Approach 
   Professor Paul W. Mielke, Jr. 
   Colorado State University 

 • Approaches to the Analysis of Microarray Data 
   and Related Issues 
   Profs Elisabetta Manduchi and Warren Ewens 
   University of Pennsylvania  
 
 • Experimental Design and the Statistical Analysis 
   of Spotted Microarrays 
   Professor Kathleen Kerr 
   University of Washington 

 • Challenges Posed by the Human Genome Project 
   Professor Warren Gish 
   Washington University in St. Louis
 
   Measurement Error in Nonlinear Models 
   Professor David Ruppert 
   Cornell University 
 
 


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nonlinear regression comparison

2001-07-15 Thread Alfred Barron

Guess what folks, after reviewing my assay data
closely, it occured to me that it is relatively
nonlinear. So I've been reviewing some notes 
from a short course on applied nonlinear regression
taught by George Milliken. While these may not be
available to most of you, he cites a related ref.
in Milliken and DeBruin (1978)A procedure to test
hypotheses for nonlinear models, Comm.Stat.Theor.
Meth.,A(71):65-79.

Al 
=
Date: Fri, 13 Jul 2001 11:26:00 -0700 (PDT)
From: Alfred Barron [EMAIL PROTECTED]
Subject: parallel-line assay

I have to compare treatment dose-response assay 
data. This can be done using regression as in
Finney's book (among other references). However,
I understand that non-parametric tests for the
parallelism of 2 regression lines was coded in SAS
in the late 70s. While I have some old proc matrix
code described in SAS SUGI 4 (1979) to do it, does
anyone have something more current that is online
somewhere or that they could share ?

My study involves bacterial strains measured under
different treatment conditions.

thanks,
Al Barron
Metuchen, NJ

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parallel-line assay

2001-07-13 Thread Alfred Barron

I have to compare treatment dose-response assay 
data. This can be done using regression as in
Finney's book (among other references). However,
I understand that non-parametric tests for the
parallelism of 2 regression lines was coded in SAS
in the late 70s. While I have some old proc matrix
code described in SAS SUGI 4 (1979) to do it, does
anyone have something more current that is online
somewhere or that they could share ?

My study involves bacterial strains measured under
different treatment conditions.

thanks,
Al Barron
Metuchen, NJ


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teaching probability statistics

2001-05-31 Thread Alfred Barron

Karen,

I'm forwarding your request to the edstat list.
You may also want to look into the AP statistics 
list. Look these up using  www.google.com   by
using the search words AP Statistics.

Al
===

Date: 30 May 01 21:41:32 -0400 (EDT)
From: Karen Rigsby [EMAIL PROTECTED]
Subject: teaching probability  statistics

I am doing a research paper on teaching probability
and statistics and
am interested in the results of your study. Is that
posted anywhere
on the web?  Thank you.


=
Alfred M. Barron
NonClinical Biostatistics
R. W. Johnson Pharmaceutical Research Institute
1000 Route 202, OMP Rm. G-35
Raritan, NJ 08869

[908] 704-4102
[EMAIL PROTECTED]
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ANOVA and regression

2001-05-31 Thread Alfred Barron

The relation between ANOVA and regression goes
to the heart of the linear model; they are, at
once, both inter-connected aspects of the linear 
model. In fact, one could interpret ANOVA as
regression on indicator variables. If you want 
to go further, one could contrast linear modeling 
ingeneral with experimental design as well. Again,
both are inter-connected.

This perspective is outlined well in the Kutner,
Neter,  Wasserman books on linear models. There 
there are 2 or 3 versions on the market, in 
various editions. The current one is called
Applied Linear Statistical Models.

A more theoretical approach can be found in 
Searle's Linear Models. 

No false placebo effect here !

Al

===
Alfred M. Barron
NonClinical Biostatistics
R. W. Johnson Pharmaceutical Research Institute
1000 Route 202, OMP Rm. G-35
Raritan, NJ 08869

[908] 704-4102
[EMAIL PROTECTED]
===



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multivariate normality

2001-04-06 Thread Alfred Barron

May I suggest you email the authors of the SAS book
"Applied Multivariate Statistics with SAS Software"
that describes the MV macro.

Al Barron,
Metuchen, NJ


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multivariate normality

2001-04-05 Thread Alfred Barron

May I suggest you email the authors of the SAS book
on Applied Multivariate Statistics that describes 
the MV macro.

Al Barron,
Metuchen, NJ


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Election Data

2001-03-25 Thread Alfred Barron

I'd like to model some past voter data to help
assess voter trends (predict election outcomes ?)
and preferences.

Does anyone have any references ? Texts and
websites would be approciated.

Is most of this done using some form of logistic
regression ?

Al Barron
Metuchen, NJ

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Time to an event (retirement)

2001-03-09 Thread Alfred Barron

Hi everyone,

The event I'm interested in is an estimate of time 
to retirement (or attrition) of our staff.

A brief subset of my data looks like,

  SUB  AGE   HIRED   RETIRED ACTIVE

  150   09/15/7006/15/90   0
  245   09/12/7506/15/92   0
  352   09/13/72  .1
  455   09/15/70  .1
  535   09/17/90  .1
  ...etc...

The variables are SUB (subject), AGE, HIRED (date
hired), RETIRED (date retired or quit), and ACTIVE
(0=retired, 1=employed). This appears to be fairly
standard data.

Could anyone suggest a working model in SAS ? I'm
considering PROC LIFEREG with Allison's PREDICT
macro (as described in his 1995 book). Maybe use
age as a covariate...

Any suggestions on this ? Is this in the published
literature ? Survival analysis is new to me. For
the curious, I'm trying to get a rough estimate of
the number of people taking retirement this year
for our budget planning. I'm on the local Board of
Education.

thanks,
Al Barron
Metuchen, NJ




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