[Freesurfer] TRACUAL eddy_correct Usage

2018-08-13 Thread Timothy Hendrickson
External Email - Use Caution

Hello,

I notice that within TRACULA 6.0 that eddy_correct is used for the eddy
current correction. This is an older tool as compared to eddy, is there a
reason that eddy_correct is still used? Have you done cross comparisons
between eddy_correct and eddy? If so did you find much difference in eddy
current corrections?

Thanks!

-Tim
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[Freesurfer] mri_convert

2018-04-24 Thread Timothy Hendrickson
External Email - Use Caution

 Hello,

I am working on implementing third party designed code which runs
freesurfer via the containerization tool docker. This code runs fine within
docker so that it is not the problem. I am attempting to run this same code
with a tool named udocker which is a tool that emulates a docker
environment but does not require root user privileges in order to do so.

Anyway long story short when I attempt to run the udocker container of
freesurfer 5.3.0-HCP with the default backend (PRoot) I receive a mmap
error with mri_convert which reads: PROT_EXEC | PROT_WRITE. I am able to
work around this error in certain instances, but that is not important
here. What is important is that when I run a udocker container with
freesurfer 6 mri_convert runs without issue.

My two questions are:

1) What differences exist between mri_convert between freesurfer 6 and
5.3.0 - HCP
2) Is there any way that I can download/install the newer version of
mri_convert used for freesurfer 6 within 5.3.0 - HCP?

-Tim
Timothy Hendrickson
Neuroimaging Analyst/Staff Scientist
University of Minnesota Informatics Institute
University of Minnesota
Bioinformatics M.S. Candidate
Office: 612-624-0783
Mobile: 507-259-3434 (texts okay)
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Re: [Freesurfer] Continuous co-variate by continuous co-variate interaction effects

2017-08-24 Thread Timothy Hendrickson
Hi Doug,

Yes thank you this was my contrast matrix, not my design matrix. I've taken
your advice by multiplying the co-variates together.

Thanks for the help!

-Tim
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[Freesurfer] Continuous co-variate by continuous co-variate interaction effects

2017-08-23 Thread Timothy Hendrickson
Freesurfer experts,

I have created a design matrix in order to test for whether there is an
interaction effect between two continuous co-variates controlling for a
categorical variable.

So I have one categorical variable with two levels, and two continuous
co-variates.

My design matrix is as follows:

0 0 1 1 0 0
0 0 0 0 1 1

Is this correct?

-Tim

Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Bioinformatics and Computational Biology M.S. Candidate
Office: 612-624-6441
Mobile: 507-259-3434 (texts okay)
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addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
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Re: [Freesurfer] Poorly Designed Matrix Two Stage Longitudinal Model

2016-12-22 Thread Timothy Hendrickson
Doug,

That did it! Thank you so much for your help!

-Tim

Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Office: 612-624-6441
Mobile: 507-259-3434 (texts okay)

On Wed, Dec 21, 2016 at 12:47 PM, Douglas N Greve <gr...@nmr.mgh.harvard.edu
> wrote:

> your 10th column is all 0s
>
>
> On 12/21/2016 01:26 PM, Timothy Hendrickson wrote:
> > Just following up on the message below. I would appreciate a comment on
> this issue.
> >
> > -Tim
> > FreeSurfer experts,
> >
> > I am attempting to use the two stage model for longitudinal analysis,
> > however I keep receiving an error message that my design matrix is poorly
> > scaled.
> > I'm curious, I've used the same format of design matrix on cross
> > sectional without problem.
> > Anyway here is the command line input:
> >
> >   mri_glmfit --glmdir
> > rh.AllSite.gender.group.Age.thickness.fwhm10.twoStage.glmdir \
> > --X DOSSDS.twoStage_AllSite_Gender_Group_Age.dat \
> > --y rh.testretest.thickness-spc.stack.fwhm10.mgh \
> > --C
> > DiffDiagnosis_ControlMore_AcctSite_AcctGender_AcctAge_
> pairedAnalysis.DOSSDS.mtx
> > \
> > --label rh.testretest.fsaverage.cortex.label \
> > --surf fsaverage rh
> >
> > The error message is attached within file
> > error_designMtx_12_19_16.txt
> >
> > Additionally I've included my analysis script, all timepoint qdec file,
> > temporal average qdec file, fsgd file, and design matrix.
> > Any help would be extremely beneficial.
> >
> > -Tim
> >
> > Timothy Hendrickson
> > Department of Psychiatry
> > University of Minnesota
> > Office: 612-624-6441
> > Mobile: 507-259-3434 (texts okay)
> > Design matrix --
> >   0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
> -1.878;
> >   0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
> -2.325;
> >   0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
> -1.967;
> >   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -0.552
>  0.000;
> >   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   0.000   0.000  -0.121   0.000   0.000
>  0.000;
> >   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -0.588   0.000
>  0.000;
> >   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   1.101
>  0.000;
> >   0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
> -2.205;
> >   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   0.000   0.000   0.775   0.000   0.000
>  0.000;
> >   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   0.000   0.000   1.316   0.000   0.000
>  0.000;
> >   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -0.590
>  0.000;
> >   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -1.093   0.000
>  0.000;
> >   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -1.880   0.000
>  0.000;
> >   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -2.131   0.000
>  0.000;
> >   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.632
>  0.000;
> >   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
>  0.000
> >   0.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.908
>  0.000;
> >   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  

[Freesurfer] Poorly Designed Matrix Two Stage Longitudinal Model

2016-12-21 Thread Timothy Hendrickson
Just following up on the message below. I would appreciate a comment
on this issue.

-Tim


FreeSurfer experts,

I am attempting to use the two stage model for longitudinal analysis,
however I keep receiving an error message that my design matrix is poorly
scaled.
I'm curious, I've used the same format of design matrix on cross
sectional without problem.

Anyway here is the command line input:

 mri_glmfit --glmdir
rh.AllSite.gender.group.Age.thickness.fwhm10.twoStage.glmdir \
--X DOSSDS.twoStage_AllSite_Gender_Group_Age.dat \
--y rh.testretest.thickness-spc.stack.fwhm10.mgh \
--C
DiffDiagnosis_ControlMore_AcctSite_AcctGender_AcctAge_pairedAnalysis.DOSSDS.mtx
\
--label rh.testretest.fsaverage.cortex.label \
--surf fsaverage rh

The error message is attached within file
error_designMtx_12_19_16.txt

Additionally I've included my analysis script, all timepoint qdec file,
temporal average qdec file, fsgd file, and design matrix.
Any help would be extremely beneficial.

-Tim

Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Office: 612-624-6441
Mobile: 507-259-3434 (texts okay)

Design matrix --
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -1.878;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -2.325;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -1.967;
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -0.552   0.000;
 1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000  -0.121   0.000   0.000   0.000;
 0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000  -0.588   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   1.101   0.000;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -2.205;
 1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.775   0.000   0.000   0.000;
 1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   1.316   0.000   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -0.590   0.000;
 0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000  -1.093   0.000   0.000;
 0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000  -1.880   0.000   0.000;
 0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000  -2.131   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.632   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.908   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000   1.447   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   1.000   0.000   0.000   0.000  -1.635   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   1.000   0.000   0.000   0.000  -0.859   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   1.000   0.000   0.000   0.000  -0.588   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   1.000   0.000   0.000   0.000  -0.858   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000  -0.051;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   1.000   0.000   0.000   0.000  -1.641   0.000   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.217;
 0.000   0.000   0.000   0.000

[Freesurfer] Poorly Designed Matrix Two Stage Longitudinal Model

2016-12-19 Thread Timothy Hendrickson
FreeSurfer experts,

I am attempting to use the two stage model for longitudinal analysis,
however I keep receiving an error message that my design matrix is poorly
scaled.
I'm curious, I've used the same format of design matrix on cross
sectional without problem.

Anyway here is the command line input:

 mri_glmfit --glmdir
rh.AllSite.gender.group.Age.thickness.fwhm10.twoStage.glmdir \
--X DOSSDS.twoStage_AllSite_Gender_Group_Age.dat \
--y rh.testretest.thickness-spc.stack.fwhm10.mgh \
--C 
DiffDiagnosis_ControlMore_AcctSite_AcctGender_AcctAge_pairedAnalysis.DOSSDS.mtx
\
--label rh.testretest.fsaverage.cortex.label \
--surf fsaverage rh

The error message is attached within file
error_designMtx_12_19_16.txt

Additionally I've included my analysis script, all timepoint qdec file,
temporal average qdec file, fsgd file, and design matrix.
Any help would be extremely beneficial.

-Tim

Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Office: 612-624-6441
Mobile: 507-259-3434 (texts okay)
Design matrix --
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -1.878;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -2.325;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -1.967;
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -0.552   0.000;
 1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000  -0.121   0.000   0.000   0.000;
 0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000  -0.588   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   1.101   0.000;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -2.205;
 1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.775   0.000   0.000   0.000;
 1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   1.316   0.000   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  -0.590   0.000;
 0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000  -1.093   0.000   0.000;
 0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000  -1.880   0.000   0.000;
 0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000  -2.131   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.632   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.908   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000   1.447   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   1.000   0.000   0.000   0.000  -1.635   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   1.000   0.000   0.000   0.000  -0.859   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   1.000   0.000   0.000   0.000  -0.588   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   1.000   0.000   0.000   0.000  -0.858   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000  -0.051;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   1.000   0.000   0.000   0.000  -1.641   0.000   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.217;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000

[Freesurfer] Trouble with Two Stage Longitudinal Analysis

2016-11-28 Thread Timothy Hendrickson
I was able to figure out my design matrix issue. I had not originally
appreciated that there were no data sets from a particular class.


Thanks!

-Tim





FreeSurfer experts,

I am attempting to use the two stage model for longitudinal analysis,
however I keep receiving an error message that my design matrix is poorly
scaled.
I belive I have cross-checked my qdec, fsgd, design matrix, and contrast
files and they all match so  I do not think the problem is a mismatch.
I am wondering if I made some sort of mistake in my script design or design
matrix creation...

Anyway here is the command line input:

mri_glmfit --glmdir
lh.AllSite.gender.group.Age.thickness.fwhm10.twoStage.glmdir --X
DOSSDS.twoStage_AllSite_Gender_Group_Age.dat --y
lh.testretest.thickness-pc1.stack.fwhm10.mgh --C
age_AcctGroup_AcctSite_AcctGender_twoStage.DOSSDS.mtx --C
DiffDiagnosis_ControlMore_AcctSite_AcctGender_AcctAge_twoStage.DOSSDS.mtx
--C
DiffDiagnosis_ControlMore_AgeSlope_AcctSite_AcctGender_twoStage.DOSSDS.mtx
--C DiffGender_MaleMore_AcctSite_AcctDiagnosis_AcctAge_twoStage.DOSSDS.mtx
--C DiffGender_MaleMore_AgeSlope_AcctSite_AcctDiagnosis_twoStage.DOSSDS.mtx
--label lh.testretest.fsaverage.cortex.label --surf fsaverage lh

The error message is attached within file
AllSite_twoStageLongitudinal_DsgnMtxErr.txt

Additionally I've included my analysis script, all timepoint qdec file,
temporal average qdec file, fsgd file, and design matrix.

-Tim


Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Office: 612-624-6441
Mobile: 507-259-3434 (texts okay)

Design matrix --
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   12.600   0.000;
 1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   13.800   0.000   0.000   0.000;
 0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   12.500   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   17.200   0.000;
 1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   16.295   0.000   0.000   0.000;
 1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   17.800   0.000   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   12.495   0.000;
 0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   11.095   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   15.895   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000   16.665   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   11.745   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   12.500   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000   13.995;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000   14.740;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   11.265   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   16.240   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   1.000   0.000   0.000   0.000   13.415   0.000   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   14.835   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   1.000   0.000   0.000   0.000   14.240   0.000   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   1.000   0.000   0.000   0.000   11.835   0.000   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   16.825   0.000   0.000;
 0.000   0.000   0.000   0.000

[Freesurfer] Trouble with Two Stage Longitudinal Analysis

2016-11-23 Thread Timothy Hendrickson
FreeSurfer experts,

I am attempting to use the two stage model for longitudinal analysis,
however I keep receiving an error message that my design matrix is poorly
scaled.
I belive I have cross-checked my qdec, fsgd, design matrix, and contrast
files and they all match so  I do not think the problem is a mismatch.
I am wondering if I made some sort of mistake in my script design or design
matrix creation...

Anyway here is the command line input:

mri_glmfit --glmdir
lh.AllSite.gender.group.Age.thickness.fwhm10.twoStage.glmdir --X
DOSSDS.twoStage_AllSite_Gender_Group_Age.dat --y
lh.testretest.thickness-pc1.stack.fwhm10.mgh --C
age_AcctGroup_AcctSite_AcctGender_twoStage.DOSSDS.mtx --C
DiffDiagnosis_ControlMore_AcctSite_AcctGender_AcctAge_twoStage.DOSSDS.mtx
--C
DiffDiagnosis_ControlMore_AgeSlope_AcctSite_AcctGender_twoStage.DOSSDS.mtx
--C DiffGender_MaleMore_AcctSite_AcctDiagnosis_AcctAge_twoStage.DOSSDS.mtx
--C DiffGender_MaleMore_AgeSlope_AcctSite_AcctDiagnosis_twoStage.DOSSDS.mtx
--label lh.testretest.fsaverage.cortex.label --surf fsaverage lh

The error message is attached within file
AllSite_twoStageLongitudinal_DsgnMtxErr.txt

Additionally I've included my analysis script, all timepoint qdec file,
temporal average qdec file, fsgd file, and design matrix.

-Tim


Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Office: 612-624-6441
Mobile: 507-259-3434 (texts okay)
Design matrix --
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   12.600   0.000;
 1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   13.800   0.000   0.000   0.000;
 0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   12.500   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   17.200   0.000;
 1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   16.295   0.000   0.000   0.000;
 1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   17.800   0.000   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   12.495   0.000;
 0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   11.095   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   15.895   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000   16.665   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   11.745   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   12.500   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000   13.995;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000   14.740;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   11.265   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   16.240   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   1.000   0.000   0.000   0.000   13.415   0.000   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   14.835   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   1.000   0.000   0.000   0.000   14.240   0.000   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   1.000   0.000   0.000   0.000   11.835   0.000   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   16.825   0.000   0.000;
 0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000   0.000  
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   16.835

[Freesurfer] Fwd: [HCP-Users] HCP to FreeSurfer Resampling

2016-11-22 Thread Timothy Hendrickson
Just following up on the message below.

Respectfully,

-Tim



FreeSurfer experts,

I am attempting to resample HCP data into FreeSurfer space with the
following how to document: https://wiki.humanconnectome.
org/display/PublicData/HCP+Users+FAQ.
<https://wiki.humanconnectome.org/display/PublicData/HCP+Users+FAQ>
I believe I have resampled the GIFTI file into fs_average space, however I
am running to problems visualizing it in freeview or tksurfer. Please see
the error message in the forwarded message below?

-Tim

Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Mobile: 507-259-3434 (texts okay)

-- Forwarded message --
From: Timothy Hendrickson <hendr...@umn.edu>
Date: Tue, Nov 8, 2016 at 8:51 AM
Subject: Re: [HCP-Users] HCP to FreeSurfer Resampling
To: Timothy Coalson <tsc...@mst.edu>
Cc: "hcp-us...@humanconnectome.org" <hcp-us...@humanconnectome.org>


Hi Tim,

Thank you for taking a look at my script, I really appreciate it. I am now
running into another problem. After re-sampling into fs_average space I am
attempting to visualize that file as an overlay in tksurfer or freeview
(freesurfer visualization tools) however I receive the following
error: *mriseadGIFTIfile:
mris is NULL! found when parsing file rh.43242.32k_TJH_fsavg.func.gii*. I
know that freesurfer can handle GIFTI file so that is not the problem. I
wonder if the GIFTI file was created incorrectly...

Any advice?

-Tim


Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Mobile: 507-259-3434 (texts okay)

__________

Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Office: 612-624-6441
Mobile: 507-259-3434 (texts okay)
___
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer


The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.


Re: [Freesurfer] Cluster Color

2016-11-15 Thread Timothy Hendrickson
It seems that this message has been ignored. I really do need an answer on
this.

-Tim

Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Office: 612-624-6441
Mobile: 507-259-3434 (texts okay)
___
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer


The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.


[Freesurfer] Longitudinal Stream on HCP Data

2016-11-08 Thread Timothy Hendrickson
Aww thank you for clarifying Michael. I definitely misread Matthew's post.

-Tim

Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Mobile: 507-259-3434 (texts okay)
___
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer


The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.


[Freesurfer] Fwd: [HCP-Users] HCP to FreeSurfer Resampling

2016-11-08 Thread Timothy Hendrickson
FreeSurfer experts,

I am attempting to resample HCP data into FreeSurfer space with the
following how to document: https://wiki.humanconnectome.
org/display/PublicData/HCP+Users+FAQ.
<https://wiki.humanconnectome.org/display/PublicData/HCP+Users+FAQ>
I believe I have resampled the GIFTI file into fs_average space, however I
am running to problems visualizing it in freeview or tksurfer. Please see
the error message in the forwarded message below?

-Tim

Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Mobile: 507-259-3434 (texts okay)

-- Forwarded message --
From: Timothy Hendrickson <hendr...@umn.edu>
Date: Tue, Nov 8, 2016 at 8:51 AM
Subject: Re: [HCP-Users] HCP to FreeSurfer Resampling
To: Timothy Coalson <tsc...@mst.edu>
Cc: "hcp-us...@humanconnectome.org" <hcp-us...@humanconnectome.org>


Hi Tim,

Thank you for taking a look at my script, I really appreciate it. I am now
running into another problem. After re-sampling into fs_average space I am
attempting to visualize that file as an overlay in tksurfer or freeview
(freesurfer visualization tools) however I receive the following
error: *mriseadGIFTIfile:
mris is NULL! found when parsing file rh.43242.32k_TJH_fsavg.func.gii*. I
know that freesurfer can handle GIFTI file so that is not the problem. I
wonder if the GIFTI file was created incorrectly...

Any advice?

-Tim


Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Mobile: 507-259-3434 (texts okay)
___
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer


The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.


[Freesurfer] Longitudinal Stream on HCP Data

2016-11-08 Thread Timothy Hendrickson
Hi Freesurfer/HCP experts,

I am curious if there is a way to incorporate HCP data (i.e. myelin maps)
into the FreeSurfer processing stream.
Matthew Glasser mentioned in a post on the HCP mailing list about a month
back that this is being actively worked on by FreeSurfer:
http://www.mail-archive.com/hcp-users@humanconnectome.org/msg03477.html.
<http://www.mail-archive.com/hcp-users@humanconnectome.org/msg03477.html>
Are there any workflows or development versions that I can download in
order to perform something like this.

Respectfully,

-Tim

Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Mobile: 507-259-3434 (texts okay)
___
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer


The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.


Re: [Freesurfer] Two Stage Longitudinal Model

2016-10-31 Thread Timothy Hendrickson
Hi Martin,

Thank you for your reply. I am glad to hear that I am doing that correctly.
I am running into an error when I attempted to run my GLM.

I have looked at my fsgd and qdec files for errors, however I cannot seem
to find anything.

The error is in the attached .txt file named
illCondMatrix_twoStage_years_10_31_16.txt.

Additionally I've included my fsgd file for stage two and my qdec file for
stage one.

Any assistance would be extremely helpful,

-Tim



Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Mobile: 507-259-3434 (texts okay)
Normalized matrix condition is 129299
Design matrix --
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.995;
 1.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   1.010   0.000;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   1.050;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   1.000;
 0.000   1.000   0.000   0.000   0.000   0.555   0.000   0.000;
 0.000   1.000   0.000   0.000   0.000   1.010   0.000   0.000;
 0.000   1.000   0.000   0.000   0.000   1.005   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   1.010   0.000;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   1.000;
 0.000   0.000   1.000   0.000   0.000   0.000   1.000   0.000;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   1.005;
 0.000   0.000   1.000   0.000   0.000   0.000   1.035   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   1.495   0.000;
 1.000   0.000   0.000   0.000   0.995   0.000   0.000   0.000;
 0.000   1.000   0.000   0.000   0.000   1.000   0.000   0.000;
 1.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000;
 0.000   1.000   0.000   0.000   0.000   0.985   0.000   0.000;
 1.000   0.000   0.000   0.000   0.990   0.000   0.000   0.000;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.980;
 0.000   1.000   0.000   0.000   0.000   0.980   0.000   0.000;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   1.000;
 0.000   1.000   0.000   0.000   0.000   0.990   0.000   0.000;
 1.000   0.000   0.000   0.000   0.990   0.000   0.000   0.000;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.990;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   0.990;
 1.000   0.000   0.000   0.000   0.985   0.000   0.000   0.000;
 1.000   0.000   0.000   0.000   0.985   0.000   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   1.010   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.985   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   1.000   0.000;
 0.000   0.000   0.000   1.000   0.000   0.000   0.000   1.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.995   0.000;
 1.000   0.000   0.000   0.000   0.995   0.000   0.000   0.000;
 1.000   0.000   0.000   0.000   1.000   0.000   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   1.450   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.990   0.000;
 0.000   1.000   0.000   0.000   0.000   0.995   0.000   0.000;
 1.000   0.000   0.000   0.000   0.995   0.000   0.000   0.000;
 0.000   0.000   1.000   0.000   0.000   0.000   0.995   0.000;

ERROR: matrix is ill-conditioned or badly scaled, condno = 129299

Possible problem with experimental design:
Check for duplicate entries and/or lack of range of
continuous variables within a class.
If you seek help with this problem, make sure to send:
  1. Your command line:
mri_glmfit --glmdir 
rh.UMN.gender.group.Years.thickness.fwhm10.twoStage.glmdir --fsgd 
twoStageLongitudinal_BaseUMN_Gender_Group_Years.fsgd dods --y 
rh.testretest.thickness-pc1.stack.fwhm10.mgh --C 
DiffDiagnosis_ControlMore_AcctGender_AcctYearDiff_twoStage_10_25_16.mtx --C 
DiffDiagnosis_ControlMore_AcctGender_YearDiffSlope_twoStage_10_25_16.mtx --C 
DiffGender_MaleMore_AcctGroup_AcctYearDiff_twoStage_10_25_16.mtx --C 
DiffGender_MaleMore_AcctGroup_YearDiffSlope_twoStage_10_25_16.mtx --C 
YearDiff_AcctGender_AcctSite_twoStage_10_25_16.mtx --label 
rh.testretest.fsaverage.cortex.label --surf fsaverage rh 
  2. The FSGD file (if using one)
  3. And the design matrix above



twoStageLongitudinal_BaseUMN_Gender_Group_Years.fsgd
Description: Binary data


twoStage_UMN_Group_Sex_Years.table.dat
Description: Binary data
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[Freesurfer] Two Stage Longitudinal Model

2016-10-26 Thread Timothy Hendrickson
FreeSurfer Experts,

Hello I am attempting to perform a two stage longitudinal analysis. My
entire data set has two time points for each participant.
I understand that the subject order in the FSGD file should correspond with
the QDEC file run through long_mris_slopes.
In my case the FSGD file has half as many inputs as the QDEC file.

My question is would I take the covariates from TP1 and TP2 and take the
average to input into the FSGD file?

If that is the case is there anything wrong with performing the
long_qdec_table --qdec "qdec.table.dat --cross --out "cross.qdec.table.dat"
command and using that co-variate data to input into the FSGD file?

Respectfully,

-Tim

Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Mobile: 507-259-3434 (texts okay)
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[Freesurfer] mri_glmfit --pvr Assistance

2016-09-07 Thread Timothy Hendrickson
FreeSurfer Experts,

I have a data set which comprises one group and the co-variate IQ. I would
like to correlate this data set with the dependent measure LGI. I
originally performed this in QDEC, however I read elsewhere that a
vertex-by-vertex correlation cannot be done in QDEC.
Further, I read that it must be done via command line with mri_glmfit and
the --pvr flag. I am confused as to what sort of file I should input into
the --pvr flag (do I run a separate analysis?, etc).

Any advice would be extremely helpful.

Respectfully,

-Tim

Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Mobile: 507-259-3434 (texts okay)
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[Freesurfer] Performing GLM within a Mask Specified by Another GLM

2016-08-11 Thread Timothy Hendrickson
Freesurfer Support,

Here is what I would like to do:

I have run a GLM on the entire cortex to determine whether there are
significant differences in LGI between patients and controls.
I then would like run a different GLM just with the clusters outputted from
the previous GLM.
It would seem that the best thing to do is to set a mask representing the
clusters from the first GLM and then run the second GLM on the mask.
Is this a reasonable thing to do? What steps/commands would I perform in
order to do something like this?

Respectfully,

-Tim Hendrickson

Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Mobile: 507-259-3434 (texts okay)
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[Freesurfer] Design Matrix Creation

2016-07-06 Thread Timothy Hendrickson
Hi Doug,

I just wanted to make sure that we were on the same page. I may have
been a little unclear in what I would ideally like to do.

For #2 what I would like to do is take into account age slopes and
total intracranial slopes for gender, and age slopes and total
intracranial slopes for diagnosis.
I was not implying that I wanted diagnosis and gender to interact.

Assuming that you understood this previously could you please explain
why you would model the matrix this way? I do not fully understand.

Respectfully,

-Tim


>I did not get the same matrix. Here's how I would do it
>Columns 1-16 model the intercepts for all your classes
>Columns 17-20 model the ages for your gender-x-diagnosis subclasses
>Columns 21-24 model the ICV for your gender-x-diagnosis subclasses

On 07/06/2016 02:04 PM, Timothy Hendrickson wrote:
> Freesurfer Support,
>
> Thank you for your support with my previous line of questions regarding
> design matrix creation.
> I have manually created another design matrix and want to ensure that I
> designed it correctly.
>
> An example of my FSGD file is as follows below:
> Class SITE 1-Male-Control
> Class SITE 1-Male-PATIENT
> Class SITE 1-Female-Control
> Class SITE 1-Female-PATIENT
> Class SITE 2-Male-Control
> Class SITE 2-Male-PATIENT
> Class SITE 2-Female-Control
> Class SITE 2-Female-PATIENT
> Class SITE 3-Male-Control
> Class SITE 3-Male-PATIENT
> Class SITE 3-Female-Control
> Class SITE 3-Female-PATIENT
> Class SITE 4-Male-Control
> Class SITE 4-Male-PATIENT
> Class SITE 4-Female-Control
> Class SITE 4-Female-PATIENT
> Variables age_at_scan total_intracranial_volume
> study site levels = 1, 2, 3, 4
> gender levels = Male, Female
> diagnosis levels = PATIENT, Control
> age_at_scan = covariate age
> total_intracranial_volume = covariate total intracranial volume
>
> What I would ideally like to do is:
>
> 1) Take into account offset differences amongst diagnosis, gender, and study
> site.
>
> 2) Allowing a difference in age slope, and total intracranial volume slope
> amongst the diagnosis and gender levels.
>
> 3) Modeling the age slope and total intracranial volume slope as the same for
> the study site levels.
> Let's image that the first participant is from site 1, Male, and control, and
> is 12 and has a TIV of 30,000.
> The second participant is from site 2, Female, and PATIENT, and is 14, and
> has a TIV of 25,000.
> My understanding of the design matrix would be as follows:
> 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 3 0 0 0
> 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 25000
> -Tim
>
> >Yes, create your matrix manually.
> >
> >Those matrix lines are not quite right. The ages are in the correct
> >column, but you need a 1 somewhere in columns 1-8 to indicate the class
> >(ie, site/dx) that the subject is in.
> On 05/26/2016 12:57 PM, Timothy Hendrickson wrote:
> > Hi Doug,
> >
> > Thank you for such a prompt response. Just to be clear you are
> > recommending that I manually create the matrix file right?
> >
> > If so I want to ensure that I am understanding how to design the
> > matrix file properly.
> >
> > Let's imagine that the first participant is a control and is 13 and
> > the second is a patient and is 15. My understanding is that the matrix
> > file would be as follows:
> > 0 0 0 0 0 0 0 0 13 0
> > 0 0 0 0 0 0 0 0 0 15.
> >
> > -Tim
> > Previous correspondences are below:
> >
> > You'll need a regressor for each of the 8 classes you describe below.
> > You can use mri_glmfit to generate this (Xg.dat file)
> > You'll need two more regressors for age, one for each diagnosis. If a
> > subject (ie, row) is a control then the two values will be AGE 0. If the
> > subject of the row is a patient, then the two values will be 0 AGE. You
> > can then set up a Controls-Patients age (ie, interaction between dx and
> > age) contrast like
> > [0 0 0 0 0 0 0 0 1 -1]
> > On 05/24/2016 02:30 PM, Timothy Hendrickson wrote:
> > >
> > > Freesurfer Support,
> > >
> > > I'd like to create a design matrix for a group analysis outside of the
> > > DODS and DOSS models. I understand that in order to do this the -X
> > > flag must be used. However, I have been unable to find examples of how
> > > to do this.
> > >
> > > I am hoping to reveal a difference in thickness or gyrification
> > > amongst a clinical population. The data set contains two factors:
> > > diagnosis, and study site and one covariate: age. Diagnosis has two
> > > levels: controls, and patients. Study site has four levels, one level
> > > for eac

[Freesurfer] LGI Summary Statistics

2016-07-06 Thread Timothy Hendrickson
Freesurfer Support,

I have seen previous message threads on extracting LGI measurements across
ROIs, however I have yet to find anything which would provide a summary LGI
across an entire hemsphere.
Other measurements like cortical thickness have a measurement like this. Is
there a measurement like this for LGI?

If I take the mean of all of the ROIs would that be equivalent to a
hemispheric LGI measure?

Thanks!

-Tim

Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Mobile: 507-259-3434 (texts okay)
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[Freesurfer] Design Matrix Creation

2016-07-06 Thread Timothy Hendrickson
Freesurfer Support,

Thank you for your support with my previous line of questions
regarding design matrix creation.
I have manually created another design matrix and want to ensure that
I designed it correctly.

An example of my FSGD file is as follows below:
Class SITE 1-Male-Control
Class SITE 1-Male-PATIENT
Class SITE 1-Female-Control
Class SITE 1-Female-PATIENT
Class SITE 2-Male-Control
Class SITE 2-Male-PATIENT
Class SITE 2-Female-Control
Class SITE 2-Female-PATIENT
Class SITE 3-Male-Control
Class SITE 3-Male-PATIENT
Class SITE 3-Female-Control
Class SITE 3-Female-PATIENT
Class SITE 4-Male-Control
Class SITE 4-Male-PATIENT
Class SITE 4-Female-Control
Class SITE 4-Female-PATIENT
Variables age_at_scan total_intracranial_volume

study site levels = 1, 2, 3, 4

gender levels = Male, Female

diagnosis levels = PATIENT, Control

age_at_scan = covariate age

total_intracranial_volume = covariate total intracranial volume

What I would ideally like to do is:
1) Take into account offset differences amongst diagnosis, gender, and
study site.
2) Allowing a difference in age slope, and total intracranial volume
slope amongst the diagnosis and gender levels.

3) Modeling the age slope and total intracranial volume slope as the
same for the study site levels.

Let's image that the first participant is from site 1, Male, and
control, and is 12 and has a TIV of 30,000.
The second participant is from site 2, Female, and PATIENT, and is 14,
and has a TIV of 25,000.

My understanding of the design matrix would be as follows:
1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 3 0 0 0
0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 25000

-Tim



>Yes, create your matrix manually.
>
>Those matrix lines are not quite right. The ages are in the correct
>column, but you need a 1 somewhere in columns 1-8 to indicate the class
>(ie, site/dx) that the subject is in.

On 05/26/2016 12:57 PM, Timothy Hendrickson wrote:
> Hi Doug,
>
> Thank you for such a prompt response. Just to be clear you are
> recommending that I manually create the matrix file right?
>
> If so I want to ensure that I am understanding how to design the
> matrix file properly.
>
> Let's imagine that the first participant is a control and is 13 and
> the second is a patient and is 15. My understanding is that the matrix
> file would be as follows:
> 0 0 0 0 0 0 0 0 13 0
> 0 0 0 0 0 0 0 0 0 15.
>
> -Tim
> Previous correspondences are below:
>
> You'll need a regressor for each of the 8 classes you describe below.
> You can use mri_glmfit to generate this (Xg.dat file)
> You'll need two more regressors for age, one for each diagnosis. If a
> subject (ie, row) is a control then the two values will be AGE 0. If the
> subject of the row is a patient, then the two values will be 0 AGE. You
> can then set up a Controls-Patients age (ie, interaction between dx and
> age) contrast like
> [0 0 0 0 0 0 0 0 1 -1]
> On 05/24/2016 02:30 PM, Timothy Hendrickson wrote:
> >
> > Freesurfer Support,
> >
> > I'd like to create a design matrix for a group analysis outside of the
> > DODS and DOSS models. I understand that in order to do this the -X
> > flag must be used. However, I have been unable to find examples of how
> > to do this.
> >
> > I am hoping to reveal a difference in thickness or gyrification
> > amongst a clinical population. The data set contains two factors:
> > diagnosis, and study site and one covariate: age. Diagnosis has two
> > levels: controls, and patients. Study site has four levels, one level
> > for each location the data has been collected from.
> >
> > What I would ideally like to do is:
> >
> > 1) Take into account offset differences amongst diagnosis and study site.
> >
> > 2) Allowing a difference in age slope amongst the diagnosis levels
> >
> > 3) Modeling the age slope as the same for the study site levels
> >
> > My FSGD file is designed as follows
> >
> > Class SITE 1-Control
> > Class SITE 1-PATIENT
> > Class SITE 2-Control
> > Class SITE 2-PATIENT
> > Class SITE 3-Control
> > Class SITE 3-PATIENT
> > Class SITE 4-Control
> > Class SITE 4-PATIENT
> > Variables age_at_scan
> >
> > study site levels = 1,2,3 and 4
> > diagnosis levels = PATIENT and Control
> > age_at_scan = covariate age
> >
> > Any advice would be greatly appreciated.
> >
> > Respectfully,
> >
> > Tim
> >
> > --
> > Timothy Hendrickson
> > Department of Psychiatry
> > University of Minnesota
> > Mobile: 507-259-3434  (texts okay)
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The infor

Re: [Freesurfer] Design Matrix Creation

2016-05-26 Thread Timothy Hendrickson
Hi Doug,

Thank you for such a prompt response. Just to be clear you are recommending
that I manually create the matrix file right?

If so I want to ensure that I am understanding how to design the matrix
file properly.

Let's imagine that the first participant is a control and is 13 and the
second is a patient and is 15. My understanding is that the matrix file
would be as follows:
0 0 0 0 0 0 0 0 13 0
0 0 0 0 0 0 0 0 0 15.

-Tim

Previous correspondences are below:

You'll need a regressor for each of the 8 classes you describe below.
You can use mri_glmfit to generate this (Xg.dat file)
You'll need two more regressors for age, one for each diagnosis. If a
subject (ie, row) is a control then the two values will be AGE 0. If the
subject of the row is a patient, then the two values will be 0 AGE. You
can then set up a Controls-Patients age (ie, interaction between dx and
age) contrast like
[0 0 0 0 0 0 0 0 1 -1]

On 05/24/2016 02:30 PM, Timothy Hendrickson wrote:
>
> Freesurfer Support,
>
> I'd like to create a design matrix for a group analysis outside of the
> DODS and DOSS models. I understand that in order to do this the -X
> flag must be used. However, I have been unable to find examples of how
> to do this.
>
> I am hoping to reveal a difference in thickness or gyrification
> amongst a clinical population. The data set contains two factors:
> diagnosis, and study site and one covariate: age. Diagnosis has two
> levels: controls, and patients. Study site has four levels, one level
> for each location the data has been collected from.
>
> What I would ideally like to do is:
>
> 1) Take into account offset differences amongst diagnosis and study site.
>
> 2) Allowing a difference in age slope amongst the diagnosis levels
>
> 3) Modeling the age slope as the same for the study site levels
>
> My FSGD file is designed as follows
>
> Class SITE 1-Control
> Class SITE 1-PATIENT
> Class SITE 2-Control
> Class SITE 2-PATIENT
> Class SITE 3-Control
> Class SITE 3-PATIENT
> Class SITE 4-Control
> Class SITE 4-PATIENT
> Variables age_at_scan
>
> study site levels = 1,2,3 and 4
> diagnosis levels = PATIENT and Control
> age_at_scan = covariate age
>
> Any advice would be greatly appreciated.
>
> Respectfully,
>
> Tim
>
> --
> Timothy Hendrickson
> Department of Psychiatry
> University of Minnesota
> Mobile: 507-259-3434  (texts okay)
>
>
> ___
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> Freesurfer@nmr.mgh.harvard.edu
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-- 
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MGH-NMR centergr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: 
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On Tue, May 24, 2016 at 1:30 PM, Timothy Hendrickson <hendr...@umn.edu>
wrote:

>
> Freesurfer Support,
>
> I'd like to create a design matrix for a group analysis outside of the
> DODS and DOSS models. I understand that in order to do this the -X flag
> must be used. However, I have been unable to find examples of how to do
> this.
>
> I am hoping to reveal a difference in thickness or gyrification amongst a
> clinical population. The data set contains two factors: diagnosis, and
> study site and one covariate: age. Diagnosis has two levels: controls, and
> patients. Study site has four levels, one level for each location the data
> has been collected from.
>
> What I would ideally like to do is:
>
> 1) Take into account offset differences amongst diagnosis and study site.
>
> 2) Allowing a difference in age slope amongst the diagnosis levels
>
> 3) Modeling the age slope as the same for the study site levels
>
> My FSGD file is designed as follows
>
> Class SITE 1-Control
> Class SITE 1-PATIENT
> Class SITE 2-Control
> Class SITE 2-PATIENT
> Class SITE 3-Control
> Class SITE 3-PATIENT
> Class SITE 4-Control
> Class SITE 4-PATIENT
> Variables age_at_scan
>
> study site levels = 1,2,3 and 4
> diagnosis levels =

[Freesurfer] Design Matrix Creation

2016-05-24 Thread Timothy Hendrickson
Freesurfer Support,

I'd like to create a design matrix for a group analysis outside of the DODS
and DOSS models. I understand that in order to do this the -X flag must be
used. However, I have been unable to find examples of how to do this.

I am hoping to reveal a difference in thickness or gyrification amongst a
clinical population. The data set contains two factors: diagnosis, and
study site and one covariate: age. Diagnosis has two levels: controls, and
patients. Study site has four levels, one level for each location the data
has been collected from.

What I would ideally like to do is:

1) Take into account offset differences amongst diagnosis and study site.

2) Allowing a difference in age slope amongst the diagnosis levels

3) Modeling the age slope as the same for the study site levels

My FSGD file is designed as follows

Class SITE 1-Control
Class SITE 1-PATIENT
Class SITE 2-Control
Class SITE 2-PATIENT
Class SITE 3-Control
Class SITE 3-PATIENT
Class SITE 4-Control
Class SITE 4-PATIENT
Variables age_at_scan

study site levels = 1,2,3 and 4
diagnosis levels = PATIENT and Control
age_at_scan = covariate age

Any advice would be greatly appreciated.

Respectfully,

Tim

-- 
Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Mobile: 507-259-3434 (texts okay)
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contains patient information, please contact the Partners Compliance HelpLine at
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Re: [Freesurfer] Cluster Color

2016-05-20 Thread Timothy Hendrickson
I'm just following up on this e-mail. I have not heard anything yet.

-Tim

On Mon, May 9, 2016 at 3:16 PM, Timothy Hendrickson <hendr...@umn.edu>
wrote:

> Free Surfer Support,
>
> I have been using the command line version for group analysis since my
> data set has too many factors for QDEC.
>
> There are a few things that I enjoy about QDEC that I wish I could
> incorporate into the command line.
>
> 1) In QDEC the cluster color is not set arbitrarily, but rather based on
> significance.
>
> Is there any way to have the cluster color be set based on significance at
> command line?
>
> Is there a way to restrict the available colors that the clusters can be
> set as?
> Occasionally, cluster colors are a very similar color to the inflated
> underlay making it difficult to determine the outline of said cluster.
>
> 2) In QDEC one is able to visualize a scatter plot for a particular
> cluster. Is there any way to do this via the command line option?
>
> Thank you,
>
> -Tim Hendrickson
>
> --
> Timothy Hendrickson
> Department of Psychiatry
> University of Minnesota
> Mobile: 507-259-3434 (texts okay)
>



-- 
Timothy Hendrickson
Department of Psychiatry
University of Minnesota
Mobile: 507-259-3434 (texts okay)
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