Re: [Freesurfer] white matter errors due to inhomogeneities (bright spots) in cortex
Not sure it's helpful. The simplest way I can think of is to directly edit WM.mgz. You can load wm.mgz into matlab, it's basically a 3D matrix. You can directly set values for wm matrix, for instance wm(wm(:)>200)=110; Then you save the new wm matrix into wm.mgz. On 9/5/16 10:54 AM, Benjamin Baird wrote: Hi Bruce and Clara, Many thanks for your comments. Indeed the bright points are segmented as WM in wm.mgz, however these errors do not occur only in a few places but in many slices throughout the brain so manual edits will be very extensive, which is why we wanted to double check that there is no parameter tweak to recon that might at least help some of these errors. But sounds like there's no way to adjust the parameters of recon to mitigate this type of error? If not we will move forward with manual edits to wm.mgz as you suggest. Also I'm wondering if this is a common issue with GE scanners, as I've never encountered it before on Siemens, and I recently saw a post to the FS group from someone else encountering the same issue on GE Best regards, Ben On Fri, Sep 2, 2016 at 8:36 AM, Clara Kühn <cku...@cbs.mpg.de <mailto:cku...@cbs.mpg.de>> wrote: Hello Ben, I am no expert, I can only talk from my experience. I've had similar images in my data. Those might be blood vessels or dura that were included in the surface. If they are included in the surface on more than 5 slices and pretty well visible you could delete those voxels from the brainmask. From the looks of the attached screenshots however I wouldn't worry about the brainmask but rather remove a few voxels from the wm.mgz. Then you rerun the subject with the -wm flag and check again. If it is only on one or two slices, though, I wouldn't edit it at all. The surfaces are just not going to be perfect. Hope I could help. Clara - Ursprüngliche Mail - Von: "Benjamin Baird" <benjamin.s.ba...@gmail.com <mailto:benjamin.s.ba...@gmail.com>> An: freesurfer@nmr.mgh.harvard.edu <mailto:freesurfer@nmr.mgh.harvard.edu> Gesendet: Donnerstag, 1. September 2016 21:56:58 Betreff: [Freesurfer] white matter errors due to inhomogeneities (brightspots) in cortex Dear Freesurfer experts, We are currently working with some scans that were collected on a GE 3T scanner. The goal is to analyze cortical thickness. The scans seem to be relatively high quality with the exception that there are what appear to be inhomogeneities in the intensity of the gray matter (appears too bright in places), which is causing the WM to extend/jump into cortex (see attached image). We're wondering if there are any parameter adjustments to recon that might help with this as the errors occur frequently enough that fixing them all manually will be fairly cumbersome. This type of error doesn’t seem to be discussed very much in the available information on freesurfer quality control as far as we’ve seen. Thanks in advance for any advice you might be able to offer. Best regards, Ben ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu <mailto:Freesurfer@nmr.mgh.harvard.edu> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer> The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline <http://www.partners.org/complianceline> . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu <mailto:Freesurfer@nmr.mgh.harvard.edu> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer> The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline <http://www.partners.org/complianceline> . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information
Re: [Freesurfer] white matter errors due to inhomogeneities (bright spots) in cortex
Hi Ben sorry, but I don't know how to fix it automatically. You have voxels that look just like wm in the gm - that's going to be tough to avoid. You could try messing with some of the mris_make_surfaces options, but I don't have much confidence that it will help. Any idea why you are getting the bright voxels in the first place? Bruce On Mon, 5 Sep 2016, Benjamin Baird wrote: Hi Bruce and Clara, Many thanks for your comments. Indeed the bright points are segmented as WM in wm.mgz, however these errors do not occur only in a few places but in many slices throughout the brain so manual edits will be very extensive, which is why we wanted to double check that there is no parameter tweak to recon that might at least help some of these errors. But sounds like there's no way to adjust the parameters of recon to mitigate this type of error? If not we will move forward with manual edits to wm.mgz as you suggest. Also I'm wondering if this is a common issue with GE scanners, as I've never encountered it before on Siemens, and I recently saw a post to the FS group from someone else encountering the same issue on GE Best regards, Ben On Fri, Sep 2, 2016 at 8:36 AM, Clara Kühn <cku...@cbs.mpg.de> wrote: Hello Ben, I am no expert, I can only talk from my experience. I've had similar images in my data. Those might be blood vessels or dura that were included in the surface. If they are included in the surface on more than 5 slices and pretty well visible you could delete those voxels from the brainmask. From the looks of the attached screenshots however I wouldn't worry about the brainmask but rather remove a few voxels from the wm.mgz. Then you rerun the subject with the -wm flag and check again. If it is only on one or two slices, though, I wouldn't edit it at all. The surfaces are just not going to be perfect. Hope I could help. Clara - Ursprüngliche Mail - Von: "Benjamin Baird" <benjamin.s.ba...@gmail.com> An: freesurfer@nmr.mgh.harvard.edu Gesendet: Donnerstag, 1. September 2016 21:56:58 Betreff: [Freesurfer] white matter errors due to inhomogeneities (bright spots) in cortex Dear Freesurfer experts, We are currently working with some scans that were collected on a GE 3T scanner. The goal is to analyze cortical thickness. The scans seem to be relatively high quality with the exception that there are what appear to be inhomogeneities in the intensity of the gray matter (appears too bright in places), which is causing the WM to extend/jump into cortex (see attached image). We're wondering if there are any parameter adjustments to recon that might help with this as the errors occur frequently enough that fixing them all manually will be fairly cumbersome. This type of error doesn’t seem to be discussed very much in the available information on freesurfer quality control as far as we’ve seen. Thanks in advance for any advice you might be able to offer. Best regards, Ben ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail wa
Re: [Freesurfer] white matter errors due to inhomogeneities (bright spots) in cortex
Hi Bruce and Clara, Many thanks for your comments. Indeed the bright points are segmented as WM in wm.mgz, however these errors do not occur only in a few places but in many slices throughout the brain so manual edits will be very extensive, which is why we wanted to double check that there is no parameter tweak to recon that might at least help some of these errors. But sounds like there's no way to adjust the parameters of recon to mitigate this type of error? If not we will move forward with manual edits to wm.mgz as you suggest. Also I'm wondering if this is a common issue with GE scanners, as I've never encountered it before on Siemens, and I recently saw a post to the FS group from someone else encountering the same issue on GE Best regards, Ben On Fri, Sep 2, 2016 at 8:36 AM, Clara Kühn <cku...@cbs.mpg.de> wrote: > Hello Ben, > > I am no expert, I can only talk from my experience. > I've had similar images in my data. Those might be blood vessels or dura > that were included in the surface. If they are included in the surface on > more than 5 slices and pretty well visible you could delete those voxels > from the brainmask. From the looks of the attached screenshots however I > wouldn't worry about the brainmask but rather remove a few voxels from the > wm.mgz. Then you rerun the subject with the -wm flag and check again. If it > is only on one or two slices, though, I wouldn't edit it at all. The > surfaces are just not going to be perfect. > > Hope I could help. > Clara > > > - Ursprüngliche Mail - > Von: "Benjamin Baird" <benjamin.s.ba...@gmail.com> > An: freesurfer@nmr.mgh.harvard.edu > Gesendet: Donnerstag, 1. September 2016 21:56:58 > Betreff: [Freesurfer] white matter errors due to inhomogeneities (bright > spots) in cortex > > Dear Freesurfer experts, > > We are currently working with some scans that were collected on a GE 3T > scanner. The goal is to analyze cortical thickness. The scans seem to be > relatively high quality with the exception that there are what appear to be > inhomogeneities in the intensity of the gray matter (appears too bright in > places), which is causing the WM to extend/jump into cortex (see attached > image). We're wondering if there are any parameter adjustments to recon > that might help with this as the errors occur frequently enough that fixing > them all manually will be fairly cumbersome. This type of error doesn’t > seem to be discussed very much in the available information on freesurfer > quality control as far as we’ve seen. > Thanks in advance for any advice you might be able to offer. > > Best regards, > Ben > > > > > ___ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > The information in this e-mail is intended only for the person to whom it > is > addressed. If you believe this e-mail was sent to you in error and the > e-mail > contains patient information, please contact the Partners Compliance > HelpLine at > http://www.partners.org/complianceline . If the e-mail was sent to you in > error > but does not contain patient information, please contact the sender and > properly > dispose of the e-mail. > ___ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > The information in this e-mail is intended only for the person to whom it > is > addressed. If you believe this e-mail was sent to you in error and the > e-mail > contains patient information, please contact the Partners Compliance > HelpLine at > http://www.partners.org/complianceline . If the e-mail was sent to you in > error > but does not contain patient information, please contact the sender and > properly > dispose of the e-mail. > > ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
Re: [Freesurfer] white matter errors due to inhomogeneities (bright spots) in cortex
Hi Bruce and Clara, Thanks for your comments. Indeed the bright points are segmented as WM in wm.mgz, however these errors do not occur only in a few places but in many slices throughout the brain so manual edits will be quite extensive, which is why we wanted to double check that there is no parameter tweak to recon that might at least help some of these errors. But sounds like there's no way to adjust the parameters of recon to mitigate this type of error? If not we will move forward with manual edits to wm.mgz as you suggest. Thanks! Best regards, Ben On Fri, Sep 2, 2016 at 8:36 AM, Clara Kühn <cku...@cbs.mpg.de> wrote: > Hello Ben, > > I am no expert, I can only talk from my experience. > I've had similar images in my data. Those might be blood vessels or dura > that were included in the surface. If they are included in the surface on > more than 5 slices and pretty well visible you could delete those voxels > from the brainmask. From the looks of the attached screenshots however I > wouldn't worry about the brainmask but rather remove a few voxels from the > wm.mgz. Then you rerun the subject with the -wm flag and check again. If it > is only on one or two slices, though, I wouldn't edit it at all. The > surfaces are just not going to be perfect. > > Hope I could help. > Clara > > > - Ursprüngliche Mail - > Von: "Benjamin Baird" <benjamin.s.ba...@gmail.com> > An: freesurfer@nmr.mgh.harvard.edu > Gesendet: Donnerstag, 1. September 2016 21:56:58 > Betreff: [Freesurfer] white matter errors due to inhomogeneities (bright > spots) in cortex > > Dear Freesurfer experts, > > We are currently working with some scans that were collected on a GE 3T > scanner. The goal is to analyze cortical thickness. The scans seem to be > relatively high quality with the exception that there are what appear to be > inhomogeneities in the intensity of the gray matter (appears too bright in > places), which is causing the WM to extend/jump into cortex (see attached > image). We're wondering if there are any parameter adjustments to recon > that might help with this as the errors occur frequently enough that fixing > them all manually will be fairly cumbersome. This type of error doesn’t > seem to be discussed very much in the available information on freesurfer > quality control as far as we’ve seen. > Thanks in advance for any advice you might be able to offer. > > Best regards, > Ben > > > > > ___ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > The information in this e-mail is intended only for the person to whom it > is > addressed. If you believe this e-mail was sent to you in error and the > e-mail > contains patient information, please contact the Partners Compliance > HelpLine at > http://www.partners.org/complianceline . If the e-mail was sent to you in > error > but does not contain patient information, please contact the sender and > properly > dispose of the e-mail. > ___ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > The information in this e-mail is intended only for the person to whom it > is > addressed. If you believe this e-mail was sent to you in error and the > e-mail > contains patient information, please contact the Partners Compliance > HelpLine at > http://www.partners.org/complianceline . If the e-mail was sent to you in > error > but does not contain patient information, please contact the sender and > properly > dispose of the e-mail. > > ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
Re: [Freesurfer] white matter errors due to inhomogeneities (bright spots) in cortex
Hello Ben, I am no expert, I can only talk from my experience. I've had similar images in my data. Those might be blood vessels or dura that were included in the surface. If they are included in the surface on more than 5 slices and pretty well visible you could delete those voxels from the brainmask. From the looks of the attached screenshots however I wouldn't worry about the brainmask but rather remove a few voxels from the wm.mgz. Then you rerun the subject with the -wm flag and check again. If it is only on one or two slices, though, I wouldn't edit it at all. The surfaces are just not going to be perfect. Hope I could help. Clara - Ursprüngliche Mail - Von: "Benjamin Baird" <benjamin.s.ba...@gmail.com> An: freesurfer@nmr.mgh.harvard.edu Gesendet: Donnerstag, 1. September 2016 21:56:58 Betreff: [Freesurfer] white matter errors due to inhomogeneities (bright spots) in cortex Dear Freesurfer experts, We are currently working with some scans that were collected on a GE 3T scanner. The goal is to analyze cortical thickness. The scans seem to be relatively high quality with the exception that there are what appear to be inhomogeneities in the intensity of the gray matter (appears too bright in places), which is causing the WM to extend/jump into cortex (see attached image). We're wondering if there are any parameter adjustments to recon that might help with this as the errors occur frequently enough that fixing them all manually will be fairly cumbersome. This type of error doesn’t seem to be discussed very much in the available information on freesurfer quality control as far as we’ve seen. Thanks in advance for any advice you might be able to offer. Best regards, Ben ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
Re: [Freesurfer] white matter errors due to inhomogeneities (bright spots) in cortex
Hi Ben are the bright points segmented as wm in the wm.mgz? If so, you might try erasing them and rerunning cheers Bruce On Wed, 31 Aug 2016, Benjamin Baird wrote: Dear Freesurfer experts, We are currently working with some scans that were collected on a GE 3T scanner. The goal is to analyze cortical thickness. The scans seem to be relatively high quality with the exception that there are what appear to be inhomogeneities in the intensity of the gray matter (appears too bright in places), which is causing the WM to extend/jump into cortex (see attached image). We're wondering if there are any parameter adjustments to recon that might help with this as the errors occur frequently enough that fixing them all manually will be fairly cumbersome. This type of error doesn’t seem to be discussed very much in the available information on freesurfer quality control as far as we’ve seen. Thanks in advance for any thoughts recommendations or advice you might be able to offer. Best regards, Ben ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.