Not sure it's helpful.

The simplest way I can think of is to directly edit WM.mgz. You can load wm.mgz into matlab, it's basically a 3D matrix. You can directly set values for wm matrix, for instance

wm(wm(:)>200)=110;

Then you save the new wm matrix into wm.mgz.



On 9/5/16 10:54 AM, Benjamin Baird wrote:
Hi Bruce and Clara,

Many thanks for your comments. Indeed the bright points are segmented as WM in wm.mgz, however these errors do not occur only in a few places but in many slices throughout the brain so manual edits will be very extensive, which is why we wanted to double check that there is no parameter tweak to recon that might at least help some of these errors. But sounds like there's no way to adjust the parameters of recon to mitigate this type of error? If not we will move forward with manual edits to wm.mgz as you suggest. Also I'm wondering if this is a common issue with GE scanners, as I've never encountered it before on Siemens, and I recently saw a post to the FS group from someone else encountering the same issue on GE

Best regards,
Ben

On Fri, Sep 2, 2016 at 8:36 AM, Clara Kühn <cku...@cbs.mpg.de <mailto:cku...@cbs.mpg.de>> wrote:

    Hello Ben,

    I am no expert, I can only talk from my experience.
    I've had similar images in my data. Those might be blood vessels
    or dura that were included in the surface. If they are included in
    the surface on more than 5 slices and pretty well visible you
    could delete those voxels from the brainmask. From the looks of
    the attached screenshots however I wouldn't worry about the
    brainmask but rather remove a few voxels from the wm.mgz. Then you
    rerun the subject with the -wm flag and check again. If it is only
    on one or two slices, though, I wouldn't edit it at all. The
    surfaces are just not going to be perfect.

    Hope I could help.
    Clara


    ----- Ursprüngliche Mail -----
    Von: "Benjamin Baird" <benjamin.s.ba...@gmail.com
    <mailto:benjamin.s.ba...@gmail.com>>
    An: freesurfer@nmr.mgh.harvard.edu
    <mailto:freesurfer@nmr.mgh.harvard.edu>
    Gesendet: Donnerstag, 1. September 2016 21:56:58
    Betreff: [Freesurfer] white matter errors due to inhomogeneities
    (bright        spots) in cortex

    Dear Freesurfer experts,

    We are currently working with some scans that were collected on a
    GE 3T scanner. The goal is to analyze cortical thickness. The
    scans seem to be relatively high quality with the exception that
    there are what appear to be inhomogeneities in the intensity of
    the gray matter (appears too bright in places), which is causing
    the WM to extend/jump into cortex (see attached image). We're
    wondering if there are any parameter adjustments to recon that
    might help with this as the errors occur frequently enough that
    fixing them all manually will be fairly cumbersome. This type of
    error doesn’t seem to be discussed very much in the available
    information on freesurfer quality control as far as we’ve seen.
    Thanks in advance for any advice you might be able to offer.

    Best regards,
    Ben




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