Re: [HCP-Users] HCP Young Adult Genetics Data Released on dbGaP!!

2018-04-13 Thread Juranek, Jenifer 
I hear ya...preaching to the choir.
I’ve just noticed a crusade (mainly led by geneticists). I’ve even seen folks 
put money on the table (Dorothy Bishop in the UK) for registered replication 
studies (irrespective of whether they replicate or not)! I just wanted to make 
sure I wasn’t missing another resource I could potentially tap to see what 
might be in the pipeline.
Many Thanks,
JJ

From: Elam, Jennifer <e...@wustl.edu>
Sent: Friday, April 13, 2018 11:49:17 AM
To: Juranek, Jenifer; hcp-users@humanconnectome.org
Cc: thomas.nich...@bdi.ox.ac.uk
Subject: Re: HCP Young Adult Genetics Data Released on dbGaP!!


Hi Jenifer,

There isn't a place to register hypotheses on dbGaP that I'm aware. People have 
asked for this for HCP and other shared/open datasets generally, but it would 
be difficult/impossible to scientifically police investigator's claims on a 
hypothesis (who would have the authority to police it? would it be worth the 
effort? lots of philosophical and logistical questions arise..).


Best,

Jenn

Jennifer Elam, Ph.D.
Scientific Outreach, Human Connectome Project
Washington University School of Medicine
Department of Neuroscience, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
e...@wustl.edu<mailto:e...@wustl.edu>
www.humanconnectome.org<https://urldefense.proofpoint.com/v2/url?u=http-3A__www.humanconnectome.org_=DwMF-g=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=l9uZt3cXZ2XhMs1RNkZWd4k18Pm5FVN4mR-V96TJzkM=qpgUsejCL_YwKwOS0MejzA2D26IIRGgxg90f1iJSBf0=>



From: Juranek, Jenifer <jenifer.jura...@uth.tmc.edu>
Sent: Friday, April 13, 2018 11:24:04 AM
To: Elam, Jennifer; hcp-users@humanconnectome.org
Cc: thomas.nich...@bdi.ox.ac.uk
Subject: RE: HCP Young Adult Genetics Data Released on dbGaP!!


Hi Jenn,

Thanks so much for the info.

Do folks register their hypotheses somehow in the dbGaP (transparency and 
reliability measures percolating throughout the research community…particularly 
genetics).

Cheers,

JJ



~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~

Jenifer Juranek, PhD

Director of the BRAIN Lab

Associate Professor

Department of Pediatrics

McGovern Medical School

UTHealth

713.500.8233







From: Elam, Jennifer [mailto:e...@wustl.edu]
Sent: Friday, April 13, 2018 11:16 AM
To: Juranek, Jenifer; hcp-users@humanconnectome.org
Cc: thomas.nich...@bdi.ox.ac.uk
Subject: Re: HCP Young Adult Genetics Data Released on dbGaP!!



Hi Jenifer,

I would use the search string: MH091657 OR "Human Connectome Project" to search 
PubMed for manuscripts that have correctly cited the WU-Minn-Oxford HCP grant 
(over 500 to date!).



I am not aware of papers that fit your criteria, but Tom Nichols (CC'd) would 
know what's out there (and likely what's in the pipeline) from some of the 
community.



Best,

Jenn



Jennifer Elam, Ph.D.
Scientific Outreach, Human Connectome Project
Washington University School of Medicine
Department of Neuroscience, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
e...@wustl.edu<mailto:e...@wustl.edu>
www.humanconnectome.org<https://urldefense.proofpoint.com/v2/url?u=http-3A__www.humanconnectome.org_=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=5lTvy6Wg6B_LOeHDopdvHe3rsvrZL4fUVf0hY0invSI=Ni2UWsDUMlmfG5dp9UYsUug5f-sXuQw6O2otLF2YrJw=>





From: Juranek, Jenifer 
<jenifer.jura...@uth.tmc.edu<mailto:jenifer.jura...@uth.tmc.edu>>
Sent: Thursday, April 12, 2018 10:03:18 PM
To: Elam, Jennifer; 
hcp-users@humanconnectome.org<mailto:hcp-users@humanconnectome.org>
Subject: Re: HCP Young Adult Genetics Data Released on dbGaP!!



Just curious...is there an easy way to identify manuscripts already published 
using the HCP-YA genetics data? I found it tough to search in PubMed (HCP is a 
common acronym), and the HCP website might be incomplete? Specifically, have 
any papers come out yet which went beyond heritability analyses and used a 
structural genetics approach (maybe relating to brain structure/connectivity)?
Many Thanks for any pointers you can provide.
Cheers,
Jenifer



From: 
hcp-users-boun...@humanconnectome.org<mailto:hcp-users-boun...@humanconnectome.org>
 
<hcp-users-boun...@humanconnectome.org<mailto:hcp-users-boun...@humanconnectome.org>>
 on behalf of Elam, Jennifer <e...@wustl.edu<mailto:e...@wustl.edu>>
Sent: Friday, March 2, 2018 2:45:10 PM
To: hcp-users@humanconnectome.org<mailto:hcp-users@humanconnectome.org>; 
hcp-annou...@humanconnectome.org<mailto:hcp-annou...@humanconnectome.org>
Subject: [HCP-Users] HCP Young Adult Genetics Data Released on dbGaP!!



News from the Human Connectome Project (HCP)

March 2, 2018

The Human Connectome Project (HCP) WU-Minn consortium is pleased to announce 
the release of al

Re: [HCP-Users] HCP Young Adult Genetics Data Released on dbGaP!!

2018-04-13 Thread Elam, Jennifer 
Hi Jenifer,

There isn't a place to register hypotheses on dbGaP that I'm aware. People have 
asked for this for HCP and other shared/open datasets generally, but it would 
be difficult/impossible to scientifically police investigator's claims on a 
hypothesis (who would have the authority to police it? would it be worth the 
effort? lots of philosophical and logistical questions arise..).


Best,

Jenn

Jennifer Elam, Ph.D.
Scientific Outreach, Human Connectome Project
Washington University School of Medicine
Department of Neuroscience, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
e...@wustl.edu<mailto:e...@wustl.edu>
www.humanconnectome.org<http://www.humanconnectome.org/>



From: Juranek, Jenifer <jenifer.jura...@uth.tmc.edu>
Sent: Friday, April 13, 2018 11:24:04 AM
To: Elam, Jennifer; hcp-users@humanconnectome.org
Cc: thomas.nich...@bdi.ox.ac.uk
Subject: RE: HCP Young Adult Genetics Data Released on dbGaP!!


Hi Jenn,

Thanks so much for the info.

Do folks register their hypotheses somehow in the dbGaP (transparency and 
reliability measures percolating throughout the research community…particularly 
genetics).

Cheers,

JJ



~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~

Jenifer Juranek, PhD

Director of the BRAIN Lab

Associate Professor

Department of Pediatrics

McGovern Medical School

UTHealth

713.500.8233







From: Elam, Jennifer [mailto:e...@wustl.edu]
Sent: Friday, April 13, 2018 11:16 AM
To: Juranek, Jenifer; hcp-users@humanconnectome.org
Cc: thomas.nich...@bdi.ox.ac.uk
Subject: Re: HCP Young Adult Genetics Data Released on dbGaP!!



Hi Jenifer,

I would use the search string: MH091657 OR "Human Connectome Project" to search 
PubMed for manuscripts that have correctly cited the WU-Minn-Oxford HCP grant 
(over 500 to date!).



I am not aware of papers that fit your criteria, but Tom Nichols (CC'd) would 
know what's out there (and likely what's in the pipeline) from some of the 
community.



Best,

Jenn



Jennifer Elam, Ph.D.
Scientific Outreach, Human Connectome Project
Washington University School of Medicine
Department of Neuroscience, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
e...@wustl.edu<mailto:e...@wustl.edu>
www.humanconnectome.org<https://urldefense.proofpoint.com/v2/url?u=http-3A__www.humanconnectome.org_=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=5lTvy6Wg6B_LOeHDopdvHe3rsvrZL4fUVf0hY0invSI=Ni2UWsDUMlmfG5dp9UYsUug5f-sXuQw6O2otLF2YrJw=>





From: Juranek, Jenifer 
<jenifer.jura...@uth.tmc.edu<mailto:jenifer.jura...@uth.tmc.edu>>
Sent: Thursday, April 12, 2018 10:03:18 PM
To: Elam, Jennifer; 
hcp-users@humanconnectome.org<mailto:hcp-users@humanconnectome.org>
Subject: Re: HCP Young Adult Genetics Data Released on dbGaP!!



Just curious...is there an easy way to identify manuscripts already published 
using the HCP-YA genetics data? I found it tough to search in PubMed (HCP is a 
common acronym), and the HCP website might be incomplete? Specifically, have 
any papers come out yet which went beyond heritability analyses and used a 
structural genetics approach (maybe relating to brain structure/connectivity)?
Many Thanks for any pointers you can provide.
Cheers,
Jenifer



From: 
hcp-users-boun...@humanconnectome.org<mailto:hcp-users-boun...@humanconnectome.org>
 
<hcp-users-boun...@humanconnectome.org<mailto:hcp-users-boun...@humanconnectome.org>>
 on behalf of Elam, Jennifer <e...@wustl.edu<mailto:e...@wustl.edu>>
Sent: Friday, March 2, 2018 2:45:10 PM
To: hcp-users@humanconnectome.org<mailto:hcp-users@humanconnectome.org>; 
hcp-annou...@humanconnectome.org<mailto:hcp-annou...@humanconnectome.org>
Subject: [HCP-Users] HCP Young Adult Genetics Data Released on dbGaP!!



News from the Human Connectome Project (HCP)

March 2, 2018

The Human Connectome Project (HCP) WU-Minn consortium is pleased to announce 
the release of all SNP Genotypes collected for HCP-Young Adult (HCP-YA) 
subjects on dbGaP:



Mapping the Human Connectome - Structure, Function, and Heritability: Healthy 
Young Adults (Age 22-35 Years) Including Twins and their Non-Twin Siblings
dbGaP Study Accession: phs001364.v1.p1

https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001364.v1.p1<https://urldefense.proofpoint.com/v2/url?u=https-3A__www.ncbi.nlm.nih.gov_projects_gap_cgi-2Dbin_study.cgi-3Fstudy-5Fid-3Dphs001364.v1.p1=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=1krCazzqwwoiPwmyKujuyzk7O0lrio34VpkumdS1qYg=cdfWp3LrMcNFnrZ4tfCAtctlDvxd8PdAcFiBSmHab84=>

The dbGaP data comprises array and imputed genotyping and a limited number of 
phenotypic variables (self reported sex, age, twin status, and family IDs) 
collected for 1142 of our 1206 released HCP-

Re: [HCP-Users] HCP Young Adult Genetics Data Released on dbGaP!!

2018-04-13 Thread Juranek, Jenifer 
Hi Jenn,
Thanks so much for the info.
Do folks register their hypotheses somehow in the dbGaP (transparency and 
reliability measures percolating throughout the research 
community...particularly genetics).
Cheers,
JJ

~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~
Jenifer Juranek, PhD
Director of the BRAIN Lab
Associate Professor
Department of Pediatrics
McGovern Medical School
UTHealth
713.500.8233



From: Elam, Jennifer [mailto:e...@wustl.edu]
Sent: Friday, April 13, 2018 11:16 AM
To: Juranek, Jenifer; hcp-users@humanconnectome.org
Cc: thomas.nich...@bdi.ox.ac.uk
Subject: Re: HCP Young Adult Genetics Data Released on dbGaP!!


Hi Jenifer,

I would use the search string: MH091657 OR "Human Connectome Project" to search 
PubMed for manuscripts that have correctly cited the WU-Minn-Oxford HCP grant 
(over 500 to date!).



I am not aware of papers that fit your criteria, but Tom Nichols (CC'd) would 
know what's out there (and likely what's in the pipeline) from some of the 
community.



Best,

Jenn


Jennifer Elam, Ph.D.
Scientific Outreach, Human Connectome Project
Washington University School of Medicine
Department of Neuroscience, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
e...@wustl.edu<mailto:e...@wustl.edu>
www.humanconnectome.org<https://urldefense.proofpoint.com/v2/url?u=http-3A__www.humanconnectome.org_=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=5lTvy6Wg6B_LOeHDopdvHe3rsvrZL4fUVf0hY0invSI=Ni2UWsDUMlmfG5dp9UYsUug5f-sXuQw6O2otLF2YrJw=>


From: Juranek, Jenifer 
<jenifer.jura...@uth.tmc.edu<mailto:jenifer.jura...@uth.tmc.edu>>
Sent: Thursday, April 12, 2018 10:03:18 PM
To: Elam, Jennifer; 
hcp-users@humanconnectome.org<mailto:hcp-users@humanconnectome.org>
Subject: Re: HCP Young Adult Genetics Data Released on dbGaP!!

Just curious...is there an easy way to identify manuscripts already published 
using the HCP-YA genetics data? I found it tough to search in PubMed (HCP is a 
common acronym), and the HCP website might be incomplete? Specifically, have 
any papers come out yet which went beyond heritability analyses and used a 
structural genetics approach (maybe relating to brain structure/connectivity)?
Many Thanks for any pointers you can provide.
Cheers,
Jenifer

From: 
hcp-users-boun...@humanconnectome.org<mailto:hcp-users-boun...@humanconnectome.org>
 
<hcp-users-boun...@humanconnectome.org<mailto:hcp-users-boun...@humanconnectome.org>>
 on behalf of Elam, Jennifer <e...@wustl.edu<mailto:e...@wustl.edu>>
Sent: Friday, March 2, 2018 2:45:10 PM
To: hcp-users@humanconnectome.org<mailto:hcp-users@humanconnectome.org>; 
hcp-annou...@humanconnectome.org<mailto:hcp-annou...@humanconnectome.org>
Subject: [HCP-Users] HCP Young Adult Genetics Data Released on dbGaP!!

News from the Human Connectome Project (HCP)
March 2, 2018
The Human Connectome Project (HCP) WU-Minn consortium is pleased to announce 
the release of all SNP Genotypes collected for HCP-Young Adult (HCP-YA) 
subjects on dbGaP:

Mapping the Human Connectome - Structure, Function, and Heritability: Healthy 
Young Adults (Age 22-35 Years) Including Twins and their Non-Twin Siblings
dbGaP Study Accession: phs001364.v1.p1
https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001364.v1.p1<https://urldefense.proofpoint.com/v2/url?u=https-3A__www.ncbi.nlm.nih.gov_projects_gap_cgi-2Dbin_study.cgi-3Fstudy-5Fid-3Dphs001364.v1.p1=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=1krCazzqwwoiPwmyKujuyzk7O0lrio34VpkumdS1qYg=cdfWp3LrMcNFnrZ4tfCAtctlDvxd8PdAcFiBSmHab84=>
The dbGaP data comprises array and imputed genotyping and a limited number of 
phenotypic variables (self reported sex, age, twin status, and family IDs) 
collected for 1142 of our 1206 released HCP-YA participants, including 149 
pairs of genetically-confirmed monozygotic twins (298 participants) and 94 
pairs of genetically-confirmed dizygotic twins (188 participants). Other open 
and restricted access subject variables are available in 
ConnectomeDB<https://urldefense.proofpoint.com/v2/url?u=https-3A__db.humanconnectome.org=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=1krCazzqwwoiPwmyKujuyzk7O0lrio34VpkumdS1qYg=bWE8uKTKb3gkwGUl37bm2Z4nbDvJ_RutabvREMGoUmY=>.
dbGaP download of the HCP-YA data requires authorized access through a data 
access request initiated after logging into dbGaP with an eRA 
Commons<https://urldefense.proofpoint.com/v2/url?u=https-3A__era.nih.gov_commons-2Daccount-2Dinformation.cfm=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=1krCazzqwwoiPwmyKujuyzk7O0lrio34VpkumdS1qYg=s1S298Jf8bHrEKJWixReCPUs5ympl9TGCVtnag_kiOk=>
 PI account. General instructio

Re: [HCP-Users] HCP Young Adult Genetics Data Released on dbGaP!!

2018-04-13 Thread Elam, Jennifer 
Hi Jenifer,

I would use the search string: MH091657 OR "Human Connectome Project" to search 
PubMed for manuscripts that have correctly cited the WU-Minn-Oxford HCP grant 
(over 500 to date!).


I am not aware of papers that fit your criteria, but Tom Nichols (CC'd) would 
know what's out there (and likely what's in the pipeline) from some of the 
community.


Best,

Jenn

Jennifer Elam, Ph.D.
Scientific Outreach, Human Connectome Project
Washington University School of Medicine
Department of Neuroscience, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
e...@wustl.edu<mailto:e...@wustl.edu>
www.humanconnectome.org<http://www.humanconnectome.org/>



From: Juranek, Jenifer <jenifer.jura...@uth.tmc.edu>
Sent: Thursday, April 12, 2018 10:03:18 PM
To: Elam, Jennifer; hcp-users@humanconnectome.org
Subject: Re: HCP Young Adult Genetics Data Released on dbGaP!!

Just curious...is there an easy way to identify manuscripts already published 
using the HCP-YA genetics data? I found it tough to search in PubMed (HCP is a 
common acronym), and the HCP website might be incomplete? Specifically, have 
any papers come out yet which went beyond heritability analyses and used a 
structural genetics approach (maybe relating to brain structure/connectivity)?
Many Thanks for any pointers you can provide.
Cheers,
Jenifer

From: hcp-users-boun...@humanconnectome.org 
<hcp-users-boun...@humanconnectome.org> on behalf of Elam, Jennifer 
<e...@wustl.edu>
Sent: Friday, March 2, 2018 2:45:10 PM
To: hcp-users@humanconnectome.org; hcp-annou...@humanconnectome.org
Subject: [HCP-Users] HCP Young Adult Genetics Data Released on dbGaP!!


News from the Human Connectome Project (HCP)
March 2, 2018
The Human Connectome Project (HCP) WU-Minn consortium is pleased to announce 
the release of all SNP Genotypes collected for HCP-Young Adult (HCP-YA) 
subjects on dbGaP:

Mapping the Human Connectome - Structure, Function, and Heritability: Healthy 
Young Adults (Age 22-35 Years) Including Twins and their Non-Twin Siblings
dbGaP Study Accession: phs001364.v1.p1
https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001364.v1.p1<https://urldefense.proofpoint.com/v2/url?u=https-3A__www.ncbi.nlm.nih.gov_projects_gap_cgi-2Dbin_study.cgi-3Fstudy-5Fid-3Dphs001364.v1.p1=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=1krCazzqwwoiPwmyKujuyzk7O0lrio34VpkumdS1qYg=cdfWp3LrMcNFnrZ4tfCAtctlDvxd8PdAcFiBSmHab84=>
The dbGaP data comprises array and imputed genotyping and a limited number of 
phenotypic variables (self reported sex, age, twin status, and family IDs) 
collected for 1142 of our 1206 released HCP-YA participants, including 149 
pairs of genetically-confirmed monozygotic twins (298 participants) and 94 
pairs of genetically-confirmed dizygotic twins (188 participants). Other open 
and restricted access subject variables are available in 
ConnectomeDB<https://urldefense.proofpoint.com/v2/url?u=https-3A__db.humanconnectome.org=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=1krCazzqwwoiPwmyKujuyzk7O0lrio34VpkumdS1qYg=bWE8uKTKb3gkwGUl37bm2Z4nbDvJ_RutabvREMGoUmY=>.

dbGaP download of the HCP-YA data requires authorized access through a data 
access request initiated after logging into dbGaP with an eRA 
Commons<https://urldefense.proofpoint.com/v2/url?u=https-3A__era.nih.gov_commons-2Daccount-2Dinformation.cfm=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=1krCazzqwwoiPwmyKujuyzk7O0lrio34VpkumdS1qYg=s1S298Jf8bHrEKJWixReCPUs5ympl9TGCVtnag_kiOk=>
 PI account. General instructions for submitting a successful data access 
request<https://urldefense.proofpoint.com/v2/url?u=https-3A__www.ncbi.nlm.nih.gov_projects_gap_cgi-2Dbin_GetPdf.cgi-3Fdocument-5Fname-3DGeneralAAInstructions.pdf=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=1krCazzqwwoiPwmyKujuyzk7O0lrio34VpkumdS1qYg=NOYjB-AV_ZhDLnJzisHSKO1evGbGXdeekFjQ9c6cbm4=>
 for dbGaP are linked from the blue box on the study page.
You will need to submit as part of the request:

  *   A research statement and a nontechnical summary statement describing your 
planned use of the data.
  *   The name of the institutional signing official who will certify the terms 
of use assurances on behalf of your institution.
  *   A list of all internal investigators at your institution who will share 
access to the data for the proposed research.
  *   A list of external collaborating investigators.
  *   The name of the information technology (IT) Director for your institution.
  *   Local Institutional Review Board (IRB) approval for use.

Once you are logged in and click Create/Begin a New Research Project, on the 
Choose Datasets tab of the Project Request page, un

Re: [HCP-Users] HCP Young Adult Genetics Data Released on dbGaP!!

2018-04-12 Thread Juranek, Jenifer 
Just curious...is there an easy way to identify manuscripts already published 
using the HCP-YA genetics data? I found it tough to search in PubMed (HCP is a 
common acronym), and the HCP website might be incomplete? Specifically, have 
any papers come out yet which went beyond heritability analyses and used a 
structural genetics approach (maybe relating to brain structure/connectivity)?
Many Thanks for any pointers you can provide.
Cheers,
Jenifer

From: hcp-users-boun...@humanconnectome.org 
<hcp-users-boun...@humanconnectome.org> on behalf of Elam, Jennifer 
<e...@wustl.edu>
Sent: Friday, March 2, 2018 2:45:10 PM
To: hcp-users@humanconnectome.org; hcp-annou...@humanconnectome.org
Subject: [HCP-Users] HCP Young Adult Genetics Data Released on dbGaP!!


News from the Human Connectome Project (HCP)
March 2, 2018
The Human Connectome Project (HCP) WU-Minn consortium is pleased to announce 
the release of all SNP Genotypes collected for HCP-Young Adult (HCP-YA) 
subjects on dbGaP:

Mapping the Human Connectome - Structure, Function, and Heritability: Healthy 
Young Adults (Age 22-35 Years) Including Twins and their Non-Twin Siblings
dbGaP Study Accession: phs001364.v1.p1
https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001364.v1.p1<https://urldefense.proofpoint.com/v2/url?u=https-3A__www.ncbi.nlm.nih.gov_projects_gap_cgi-2Dbin_study.cgi-3Fstudy-5Fid-3Dphs001364.v1.p1=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=1krCazzqwwoiPwmyKujuyzk7O0lrio34VpkumdS1qYg=cdfWp3LrMcNFnrZ4tfCAtctlDvxd8PdAcFiBSmHab84=>
The dbGaP data comprises array and imputed genotyping and a limited number of 
phenotypic variables (self reported sex, age, twin status, and family IDs) 
collected for 1142 of our 1206 released HCP-YA participants, including 149 
pairs of genetically-confirmed monozygotic twins (298 participants) and 94 
pairs of genetically-confirmed dizygotic twins (188 participants). Other open 
and restricted access subject variables are available in 
ConnectomeDB<https://urldefense.proofpoint.com/v2/url?u=https-3A__db.humanconnectome.org=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=1krCazzqwwoiPwmyKujuyzk7O0lrio34VpkumdS1qYg=bWE8uKTKb3gkwGUl37bm2Z4nbDvJ_RutabvREMGoUmY=>.

dbGaP download of the HCP-YA data requires authorized access through a data 
access request initiated after logging into dbGaP with an eRA 
Commons<https://urldefense.proofpoint.com/v2/url?u=https-3A__era.nih.gov_commons-2Daccount-2Dinformation.cfm=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=1krCazzqwwoiPwmyKujuyzk7O0lrio34VpkumdS1qYg=s1S298Jf8bHrEKJWixReCPUs5ympl9TGCVtnag_kiOk=>
 PI account. General instructions for submitting a successful data access 
request<https://urldefense.proofpoint.com/v2/url?u=https-3A__www.ncbi.nlm.nih.gov_projects_gap_cgi-2Dbin_GetPdf.cgi-3Fdocument-5Fname-3DGeneralAAInstructions.pdf=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=1krCazzqwwoiPwmyKujuyzk7O0lrio34VpkumdS1qYg=NOYjB-AV_ZhDLnJzisHSKO1evGbGXdeekFjQ9c6cbm4=>
 for dbGaP are linked from the blue box on the study page.
You will need to submit as part of the request:

  *   A research statement and a nontechnical summary statement describing your 
planned use of the data.
  *   The name of the institutional signing official who will certify the terms 
of use assurances on behalf of your institution.
  *   A list of all internal investigators at your institution who will share 
access to the data for the proposed research.
  *   A list of external collaborating investigators.
  *   The name of the information technology (IT) Director for your institution.
  *   Local Institutional Review Board (IRB) approval for use.

Once you are logged in and click Create/Begin a New Research Project, on the 
Choose Datasets tab of the Project Request page, under Primary Disease select 
"Connectome" to find the HCP dataset. Then proceed with your application.

Best,
WU-Minn HCP Consortium

Jennifer Elam, Ph.D.
Scientific Outreach, Human Connectome Project
Washington University School of Medicine
Department of Neuroscience, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
e...@wustl.edu<mailto:e...@wustl.edu>
www.humanconnectome.org<https://urldefense.proofpoint.com/v2/url?u=http-3A__www.humanconnectome.org_=DwMFAw=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ=qOVBcC-E3i4BGdjp2AXfXidjspuPk5EgKLbpRj4WEsg=1krCazzqwwoiPwmyKujuyzk7O0lrio34VpkumdS1qYg=biS0HiQ1df8LXCEmCDRw4a7AMtnz2juZLO9BfosTJlI=>


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[HCP-Users] HCP Young Adult Genetics Data Released on dbGaP!!

2018-03-02 Thread Elam, Jennifer 
News from the Human Connectome Project (HCP)
March 2, 2018
The Human Connectome Project (HCP) WU-Minn consortium is pleased to announce 
the release of all SNP Genotypes collected for HCP-Young Adult (HCP-YA) 
subjects on dbGaP:

Mapping the Human Connectome - Structure, Function, and Heritability: Healthy 
Young Adults (Age 22-35 Years) Including Twins and their Non-Twin Siblings
dbGaP Study Accession: phs001364.v1.p1
https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001364.v1.p1
The dbGaP data comprises array and imputed genotyping and a limited number of 
phenotypic variables (self reported sex, age, twin status, and family IDs) 
collected for 1142 of our 1206 released HCP-YA participants, including 149 
pairs of genetically-confirmed monozygotic twins (298 participants) and 94 
pairs of genetically-confirmed dizygotic twins (188 participants). Other open 
and restricted access subject variables are available in 
ConnectomeDB.

dbGaP download of the HCP-YA data requires authorized access through a data 
access request initiated after logging into dbGaP with an eRA 
Commons PI account. 
General instructions for submitting a successful data access 
request
 for dbGaP are linked from the blue box on the study page.
You will need to submit as part of the request:

  *   A research statement and a nontechnical summary statement describing your 
planned use of the data.
  *   The name of the institutional signing official who will certify the terms 
of use assurances on behalf of your institution.
  *   A list of all internal investigators at your institution who will share 
access to the data for the proposed research.
  *   A list of external collaborating investigators.
  *   The name of the information technology (IT) Director for your institution.
  *   Local Institutional Review Board (IRB) approval for use.

Once you are logged in and click Create/Begin a New Research Project, on the 
Choose Datasets tab of the Project Request page, under Primary Disease select 
"Connectome" to find the HCP dataset. Then proceed with your application.

Best,
WU-Minn HCP Consortium

Jennifer Elam, Ph.D.
Scientific Outreach, Human Connectome Project
Washington University School of Medicine
Department of Neuroscience, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
e...@wustl.edu
www.humanconnectome.org


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