[NMusers] Quantitative Clinical Pharmacology Position at GSK

[Misba Beerahee]

We have an exciting opportunity at GlaxoSmithKline (GSK) for a highly motivated 
Quantitative Clinical Pharmacologist to join our London team as part of the 
global department of Clinical Pharmacology Modelling & Simulation. This is an 
excellent role to use quantitative clinical pharmacology to accelerate the 
delivery of new medicines to patients by enhancing drug program efficiency and 
business decision quality. The work directly supports our mission to help our 
patients do more, feel better and live longer.
Responsibilities will include:

  *   Plan, execute and report translational drug-disease modelling, 
exposure-response analysis, simulation-based trial design and population 
clinical pharmacology
  *   Contribute to clinical program design, trial protocols, analysis plans, 
study reports and regulatory submissions
  *   Apply innovative techniques such as longitudinal exposure-response 
analysis, model-based meta-analysis and item-response analysis to improve data 
use and trial efficiency
  *   Present strategy and discuss outcome of model-based approaches via 
interactions with internal governance boards and regulatory agencies
  *   Promote model-informed drug discovery and development through external 
collaboration, journal publication and conference presentation
Qualification requirements:
1. A doctorate relevant to Quantitative Clinical Pharmacology, and experience 
in using modelling/simulation to solve practical problems in industry or 
academia
2. Proven skills in pharmacokinetic-pharmacodynamic and longitudinal disease 
modelling; and verifiable proficiency in pharmacometric tools NONMEM, Monolix, 
R or SAS
3. Strong drive and learning agility to build knowledge on a drug-disease 
system, symptom progression, standard of care, and trial design and endpoints
4. Demonstrated aptitude for productive collaboration in a multi-discipline 
team, using effective communication and taking personal accountability for 
timely delivery of results
5. Clear evidence of ability to make sound judgement in complex situations and 
adapt to changing business needs by prioritising multiple tasks
The job level will depend on the skills and achievements of the successful 
candidate. At GSK, we develop therapies of various modalities for a broad range 
of indications. As a member of a global department with diverse expertise, you 
will enjoy a highly supportive environment for scientific innovation, business 
impact and professional growth.
Interested persons are encouraged to apply online here  
https://jobs.gsk.com/en-gb/jobs/255771?lang=en-us&previousLocale=en-GB




GSK monitors email communications sent to and from GSK in order to protect GSK, 
our employees, customers, suppliers and business partners, from cyber threats 
and loss of GSK Information. GSK monitoring is conducted with appropriate 
confidentiality controls and in accordance with local laws and after 
appropriate consultation.



This e-mail was sent by GlaxoSmithKline Services Unlimited
(registered in England and Wales No. 1047315), which is a
member of the GlaxoSmithKline group of companies. The
registered address of GlaxoSmithKline Services Unlimited
is 980 Great West Road, Brentford, Middlesex TW8 9GS.

[NMusers] Quantitative Clinical Pharmacology Position at GSK

[Chao Chen]

We have an exciting opportunity at GlaxoSmithKline (GSK) for a highly motivated 
Quantitative Clinical Pharmacologist to join our London team as part of the 
global department of Clinical Pharmacology Modelling & Simulation. This is an 
excellent role to use quantitative clinical pharmacology to accelerate the 
delivery of new medicines to patients by enhancing drug program efficiency and 
business decision quality. The work directly supports our mission to help our 
patients do more, feel better and live longer.
Responsibilities will include:
1. Plan, execute and report translational drug-disease modelling, 
exposure-response analysis, simulation-based trial design and population 
clinical pharmacology
*   2. Contribute to clinical program design, trial protocols, analysis 
plans, study reports and regulatory submissions
*   3. Apply innovative techniques such as longitudinal exposure-response 
analysis, model-based meta-analysis and item-response analysis to improve data 
use and trial efficiency
*   4. Present strategy and discuss outcome of model-based approaches via 
interactions with internal governance boards and regulatory agencies
*   5. Promote model-informed drug discovery and development through 
external collaboration, journal publication and conference presentation
Qualification requirements:
1. A doctorate relevant to Quantitative Clinical Pharmacology, and experience 
in using modelling/simulation to solve practical problems in industry or 
academia
2. Proven skills in pharmacokinetic-pharmacodynamic and longitudinal disease 
modelling; and verifiable proficiency in pharmacometric tools NONMEM, Monolix, 
R or SAS
3. Strong drive and learning agility to build knowledge on a drug-disease 
system, symptom progression, standard of care, and trial design and endpoints
4. Demonstrated aptitude for productive collaboration in a multi-discipline 
team, using effective communication and taking personal accountability for 
timely delivery of results
5. Clear evidence of ability to make sound judgement in complex situations and 
adapt to changing business needs by prioritising multiple tasks
The job level will depend on the skills and achievements of the successful 
candidate. At GSK, we develop therapies of various modalities for a broad range 
of indications. As a member of a global department with diverse expertise, you 
will enjoy a highly supportive environment for scientific innovation, business 
impact and professional growth. This position is open for application till 
Wednesday 5th August 2019. Interested persons are encouraged to apply online 
here.
Chao Chen
Clinical Pharmacology Modelling & Simulation
GlaxoSmithKline R&D


GSK monitors email communications sent to and from GSK in order to protect GSK, 
our employees, customers, suppliers and business partners, from cyber threats 
and loss of GSK Information. GSK monitoring is conducted with appropriate 
confidentiality controls and in accordance with local laws and after 
appropriate consultation.



This e-mail was sent by GlaxoSmithKline Services Unlimited
(registered in England and Wales No. 1047315), which is a
member of the GlaxoSmithKline group of companies. The
registered address of GlaxoSmithKline Services Unlimited
is 980 Great West Road, Brentford, Middlesex TW8 9GS.

[NMusers] Quantitative Clinical Pharmacology Position at GSK

[Chao Chen]

We have an exciting opportunity at GlaxoSmithKline (GSK) for a highly motivated 
Quantitative Clinical Pharmacologist to join our London team as part of the 
global department of Clinical Pharmacology Modelling & Simulation. This is an 
excellent role to use quantitative clinical pharmacology to accelerate the 
delivery of new medicines to patients by enhancing drug program efficiency and 
business decision quality. The work directly supports our mission to help our 
patients do more, feel better and live longer. The job level will depend on the 
skills and achievements of the successful candidate.

Responsibilities will include:

*   Plan, execute and report translational drug-disease modelling, 
exposure-response analysis, simulation-based trial design and population 
clinical pharmacology
*   Contribute to clinical program design, trial protocols, analysis plans, 
study reports and regulatory submissions
*   Apply innovative techniques such as longitudinal exposure-response 
analysis, model-based meta-analysis and item-response analysis to improve data 
use and trial efficiency
*   Present strategy and discuss outcome of model-based approaches via 
interactions with governance boards and regulatory agencies
*   Promote model-informed drug discovery and development through external 
collaboration, journal publication and conference presentation

Qualification requirements:

*   A doctorate relevant to Quantitative Clinical Pharmacology, and 
experience in using modelling/simulation to solve practical problems in 
industry or academia
*   Proven skills in pharmacokinetic-pharmacodynamic and longitudinal 
disease modelling; and verifiable proficiency in pharmacometric tools NONMEM, 
Monolix, R or SAS
*   Strong drive and learning agility to build knowledge on a drug-disease 
system, symptom progression, standard of care, and trial design and endpoints
*   Demonstrated aptitude for productive collaboration in a 
multi-discipline team, using effective communication and taking personal 
accountability for timely delivery of results
*   Clear evidence of ability to make sound judgement in complex situations 
and adapt to changing business needs by prioritising multiple tasks

At GSK, we develop therapies of various modalities for a broad range of 
indications. As a member of a global department with diverse expertise, you 
will enjoy a highly supportive environment for scientific innovation, business 
impact and professional growth. This position is open for application till 
Wednesday 19th June 2019. Interested persons are encouraged to apply online 
here.

Chao Chen
Clinical Pharmacology Modelling & Simulation
GlaxoSmithKline R&D


GSK monitors email communications sent to and from GSK in order to protect GSK, 
our employees, customers, suppliers and business partners, from cyber threats 
and loss of GSK Information. GSK monitoring is conducted with appropriate 
confidentiality controls and in accordance with local laws and after 
appropriate consultation.



  

This e-mail was sent by GlaxoSmithKline Services Unlimited
(registered in England and Wales No. 1047315), which is a
member of the GlaxoSmithKline group of companies. The
registered address of GlaxoSmithKline Services Unlimited
is 980 Great West Road, Brentford, Middlesex TW8 9GS.

[NMusers] Quantitative Clinical Pharmacology Position at GSK

[Chao Chen]

GlaxoSmithKline (GSK) has an exciting position for a highly motivated 
Quantitative Clinical Pharmacologist to join our London team as a member of the 
global department of Clinical Pharmacology Modelling & Simulation. The job 
level will depend on the skills and achievements of the successful candidate. 
This is an excellent opportunity to use quantitative clinical pharmacology to 
accelerate the delivery of new medicines to patients by enhancing drug program 
efficiency and business decision quality.
Responsibilities:
*   Plan, execute and report translational drug-disease modelling, 
exposure-response analysis, simulation-based trial design and population 
clinical pharmacology
*   Contribute to asset clinical development and registration in terms of 
program plans, trial protocols, analysis plans, study reports and regulatory 
submissions
*   Assess and apply innovative techniques such as longitudinal 
exposure-response analysis, model-based meta-analysis and item-response 
analysis to maximise data use, trial efficiency and analytical power
*   Present strategy and discuss outcome of model-based approaches during 
interactions with internal governance boards and regulators
*   Promote model-informed drug discovery and development through external 
collaboration, journal publication and conference presentation

Requirements:
*   A doctorate in a field relevant to quantitative clinical pharmacology, 
and experience in using modelling/simulation to solve practical problems in 
industry or academia
*   Proven skills in pharmacokinetic-pharmacodynamic and longitudinal 
disease modelling; and verifiable proficiency in pharmacometric tools NONMEM, 
Monolix, R or SAS
*   Strong drive and learning agility to quickly build knowledge on a 
drug-disease system, symptom progression, trial design/endpoints and current 
treatments
*   Demonstrated aptitude for productive collaboration in a 
multi-discipline team, using effective communication and taking personal 
accountability for timely delivery of results
*   Clear evidence of ability to make sound judgement in complex situations 
and adapt to changing business needs by prioritising multiple tasks

At GSK, we develop therapies of various modalities for a broad range of 
indications. As a member of a global department with diverse expertise, you 
will enjoy a highly supportive environment for scientific innovation, business 
impact and professional growth. Interested persons are encouraged to apply 
online 
here.
Chao Chen
Clinical Pharmacology Modelling & Simulation
GlaxoSmithKline R&D

GSK monitors email communications sent to and from GSK in order to protect GSK, 
our employees, customers, suppliers and business partners, from cyber threats 
and loss of GSK Information. GSK monitoring is conducted with appropriate 
confidentiality controls and in accordance with local laws and after 
appropriate consultation.



  

This e-mail was sent by GlaxoSmithKline Services Unlimited
(registered in England and Wales No. 1047315), which is a
member of the GlaxoSmithKline group of companies. The
registered address of GlaxoSmithKline Services Unlimited
is 980 Great West Road, Brentford, Middlesex TW8 9GS.

[NMusers] Quantitative Clinical Pharmacology Position at GSK

[Chao Chen]

GlaxoSmithKline (GSK) is a world leading research-based pharmaceutical company 
that combines both individual talent and technical resources to create a 
platform for the delivery for strong growth in a rapidly changing healthcare 
market. Our mission is to improve the quality of human life by enabling people 
to do more, feel better and live longer. We are actively recruiting a highly 
motivated and capable Quantitative Clinical Pharmacologist in the UK to join 
our global department of Clinical Pharmacology Modelling and Simulation.

Responsibilities include

* Take a key role, in a multi-discipline team, in dose selection for 
clinical development and registration

* Apply pharmacometric methods to build knowledge, enhance trial design 
and increase decision power.

* Design and interpret trials to assess the intrinsic and extrinsic 
impact on pharmacokinetics and pharmacodynamics.

* Defend clinical pharmacology plans and results through interaction 
with internal/external stakeholders

* Innovate jointly with adjacent disciplines such as statistics, 
biology, medical, toxicology, formulation and DMPK

* Learn and apply emerging sciences and methodologies through effective 
external collaboration
Qualification requirements are

* Doctorate training and strong motivation to enable a successful 
career in quantitative clinical pharmacology

* Sound judgement and problem-solving skills, and ability to multi-task 
and deliver on time

* Effective communication skills in both written and spoken English

* Knowledge or ability to quickly learn the mechanisms, endpoints, 
progression and treatments of relevant indications

* Deep understanding of quantitative pharmacology principles and 
working knowledge of common models and software

* Experience in designing, analysing and reporting clinical studies, 
with a model-based approach where applicable

* Familiarity with current international clinical pharmacology 
regulatory requirements

* Ability to collaborate effectively while taking personal 
accountability
At GSK, we provides a highly supportive environment for scientists who are 
aspired to learn, to contribute and to make impact on business decisions 
through innovation. The position level for a successful candidate will be based 
on the person's skills and experience. Qualified candidates are encouraged to 
apply at the web site below.
https://careers.peopleclick.com/careerscp/client_gsk/external1931/gateway.do?functionName=viewFromLink&jobPostId=310324&localeCode=en-us





This e-mail was sent by GlaxoSmithKline Services Unlimited
(registered in England and Wales No. 1047315), which is a
member of the GlaxoSmithKline group of companies. The
registered address of GlaxoSmithKline Services Unlimited
is 980 Great West Road, Brentford, Middlesex TW8 9GS.

GSK monitors email communications sent to and from GSK in order to protect GSK, 
our employees, customers, suppliers and business partners, from cyber threats 
and loss of GSK Information. GSK monitoring is conducted with appropriate 
confidentiality controls and in accordance with local laws and after 
appropriate consultation.