CS***Study conclusion that Gymnema acts by increasing cell permeabiliy plus increasing insulin secretion

2005-06-13 Thread Debbie Mcdonald

snip

Examination of islet and beta-cell integrity
after exposure to GS4, by trypan blue exclusion,
indicated that concentrations of GS4 that stimulated
insulin secretion also caused increased uptake of dye.
Two gymnemic acid-enriched fractions of GS4, obtained
by size exclusion and silica gel chromatography, also
caused increases in insulin secretion concomitant with
increased trypan blue uptake. These results confirm
the stimulatory effects of G. sylvestre on insulin
release, but indicate that GS4 acts by increasing cell
permeability, rather than by stimulating exocytosis by
regulated pathways.
   
  
And what this says is that gymnema increases the
release of insulin from the pancreas, and the
mechanism is increasing cell permeability and
making
it leaky to the insulin comes out more readily.
This
is very different that increasing insulin
sensitivity (responsiveness) at the cell level in
the peripheral tissues. Releasing more insulin
actuallly worsens hyperinsulinemia, which in turn
may lower blood sugar but at the expense of
insulinemic damage throughout the system.


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CS***Study conclusion that Gymnema acts by increasing cell permeabiliy plus increasing insulin secretion

2005-06-13 Thread oldgl...@bigcountry.net
Hi Debbie,

Are you saying gymnema sylvestre acts in the same way as prescription drugs?

Thank you,

Jean

***
 
 
 And what this says is that gymnema increases the
 release of insulin from the pancreas, and the
 mechanism is increasing cell permeability and
 making it leaky to the insulin comes out more readily.
 This is very different that increasing insulin
 sensitivity (responsiveness) at the cell level in
 the peripheral tissues. Releasing more insulin
 actuallly worsens hyperinsulinemia, which in turn
 may lower blood sugar but at the expense of
 insulinemic damage throughout the system.
 
 
 --
 


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Re: CS***Study conclusion that Gymnema acts by increasing cell permeabiliy plus increasing insulin secretion

2005-06-13 Thread Debbie Mcdonald
Hi Jean,
  Those words are from a study, not mine but I would
not interpret it that way, Deb

--- oldgl...@bigcountry.net
oldgl...@bigcountry.net wrote:

 Hi Debbie,
 
 Are you saying gymnema sylvestre acts in the same
 way as prescription drugs?
 
 Thank you,
 
 Jean
 
 ***
  
  
  And what this says is that gymnema increases the
  release of insulin from the pancreas, and the
  mechanism is increasing cell permeability and
  making it leaky to the insulin comes out more
 readily.
  This is very different that increasing insulin
  sensitivity (responsiveness) at the cell level in
  the peripheral tissues. Releasing more insulin
  actuallly worsens hyperinsulinemia, which in turn
  may lower blood sugar but at the expense of
  insulinemic damage throughout the system.
  
  
  --


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