Re: [tips] schizophrenia question

[Joan Warmbold]

This theory goes way back to the 1950's and yes, there is physiological
evidence for excess of dopamine as well as deficiencies of GABA.  But the
question that is rarely asked is when did such chemicals occur?  As much
as we all know about brain plasticity, we should realize that early
experience can play a role.  And sure enough, children raised in a highly
stressful environment also reveal excess amounts of dopamine.  So, a far
more logical question is if chemical balances do exist, when were they
first noted and how related are they to early experiences?

I have provided an attachment that provides abstracts of studies that
demonstrate 1) chemical imbalances in those with schizophrenia; 2)
chemical
imbalances in children raised in stressful environments; and, 3) the cost
of attributing mental disorders to brain chemical imbalances.

Joan
jwarm...@oakton.edu

> Student asked what it was that lead to the dopamine hypothesis regarding
> schizophrenia. How did anyone get to the idea of too much dopamine? AND is
> there ANY type of physiological evidence for that?
>
> Annette
>
> Annette Kujawski Taylor, Ph.D.
> Professor, Psychological Sciences
> University of San Diego
> 5998 Alcala Park
> San Diego, CA 921210
> tay...@sandiego.edu


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Schizophreniaandchemicalimbalances.docx
Description: MS-Word 2007 document

re: [tips] schizophrenia question

[Michael Palij]

On Thu, 30 Nov 2017 13:34:18 -0800,  Annette Taylor wrote:
>Student asked what it was that lead to the dopamine hypothesis
>regarding schizophrenia. How did anyone get to the idea of too
>much dopamine? AND is there ANY type of physiological evidence
>for that

There are actually three versions of the dopamine hypothesis
(and maybe a 4th one since the publication of the article I
link to below) and a review of the development of the hypotheses
is provided in:
Howes, O. D., & Kapur, S. (2009). The dopamine hypothesis of
schizophrenia: version III-the final common pathway.
Schizophrenia bulletin, 35(3), 549-562.

And the article can be read here:
https://academic.oup.com/schizophreniabulletin/article/35/3/549/1872560

-Mike Palij
New York University
m...@nyu.edu

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RE: [tips] schizophrenia question

[R C Intrieri]

Try these

Further thoughts on the dopamine hypothesis of schizophrenia.


Kendler, Kenneth S.; Schaffner, Kenneth F.

Philosophy, Psychiatry, & Psychology, Vol 18(1), Mar 2011, 73-75

http://dx.doi.org/10.1353/ppp.2011.0012




The dopamine hypothesis of schizophrenia: An historical and philosophical
analysis.


Kendler, Kenneth S.; Schaffner, Kenneth F.

Philosophy, Psychiatry, & Psychology, Vol 18(1), Mar 2011, 41-63

http://dx.doi.org/10.1353/ppp.2011.0005






*From:* Annette Taylor [mailto:tay...@sandiego.edu]
*Sent:* Thursday, November 30, 2017 3:33 PM
*To:* Teaching in the Psychological Sciences (TIPS)
*Subject:* [tips] schizophrenia question





Student asked what it was that lead to the dopamine hypothesis regarding
schizophrenia. How did anyone get to the idea of too much dopamine? AND is
there ANY type of physiological evidence for that?



Annette


Annette Kujawski Taylor, Ph.D.

Professor, Psychological Sciences

University of San Diego

5998 Alcala Park

San Diego, CA 921210

tay...@sandiego.edu

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